NZ196293A - Preparation of 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1h 5h-benzo(ij)quinolizine-2-carboxylic acid and intermediates therefor - Google Patents

Preparation of 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1h 5h-benzo(ij)quinolizine-2-carboxylic acid and intermediates therefor

Info

Publication number
NZ196293A
NZ196293A NZ196293A NZ19629381A NZ196293A NZ 196293 A NZ196293 A NZ 196293A NZ 196293 A NZ196293 A NZ 196293A NZ 19629381 A NZ19629381 A NZ 19629381A NZ 196293 A NZ196293 A NZ 196293A
Authority
NZ
New Zealand
Prior art keywords
quinolizine
benzo
dihydro
oxo
fluoro
Prior art date
Application number
NZ196293A
Other languages
English (en)
Inventor
C Leir
K Hedberg
J Jacobson
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/122,470 external-priority patent/US4301291A/en
Priority claimed from US06/122,657 external-priority patent/US4301289A/en
Priority claimed from US06/122,599 external-priority patent/US4301288A/en
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of NZ196293A publication Critical patent/NZ196293A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ196293A 1980-02-19 1981-02-18 Preparation of 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1h 5h-benzo(ij)quinolizine-2-carboxylic acid and intermediates therefor NZ196293A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/122,470 US4301291A (en) 1980-02-19 1980-02-19 Intermediates for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid
US06/122,657 US4301289A (en) 1980-02-19 1980-02-19 Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid
US06/122,599 US4301288A (en) 1980-02-19 1980-02-19 Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid

Publications (1)

Publication Number Publication Date
NZ196293A true NZ196293A (en) 1983-09-02

Family

ID=27382802

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ196293A NZ196293A (en) 1980-02-19 1981-02-18 Preparation of 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1h 5h-benzo(ij)quinolizine-2-carboxylic acid and intermediates therefor

Country Status (6)

Country Link
JP (2) JPH0215077A (ro)
AU (1) AU524459B2 (ro)
FR (1) FR2476079A1 (ro)
GB (1) GB2069498B (ro)
IE (1) IE50928B1 (ro)
NZ (1) NZ196293A (ro)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400386A (en) * 1981-11-06 1983-08-23 Riker Laboratories, Inc. Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine
US4472407A (en) * 1983-03-17 1984-09-18 Riker Laboratories, Inc. Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu
DE3413693A1 (de) * 1984-04-11 1985-10-17 Boehringer Mannheim Gmbh, 6800 Mannheim Fluorierte anilinderivate und ihre verwendung
IT1231425B (it) * 1987-10-05 1991-12-04 Prodotti Antibiotici Spa Procedimento per la sintesi di un derivato dell'acido benzo (ij) chinolizin-2-carbossilico
CA2009664A1 (en) * 1989-02-27 1990-08-27 Philip Thiam Shin Lau Tetrahydroquinolines and method of preparation
US5043469A (en) * 1989-07-17 1991-08-27 Eastman Kodak Company Process for preparing 5-substituted aminophenols
US6777427B2 (en) 2000-09-14 2004-08-17 Kaken Pharmaceutical Co., Ltd. Tetrahydroquinoline compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793524A (fr) * 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives
ZA728444B (en) * 1971-12-30 1973-10-31 Riker Laboratories Inc Substituted benzo(ij)quinolizine-2-carboxylic acids and derivatives thereof

Also Published As

Publication number Publication date
GB2069498B (en) 1984-02-08
GB2069498A (en) 1981-08-26
JPH0416474B2 (ro) 1992-03-24
FR2476079B1 (ro) 1984-04-20
JPH0215066A (ja) 1990-01-18
AU524459B2 (en) 1982-09-16
FR2476079A1 (fr) 1981-08-21
IE810326L (en) 1981-08-19
AU6742581A (en) 1981-09-24
JPH0375541B2 (ro) 1991-12-02
IE50928B1 (en) 1986-08-20
JPH0215077A (ja) 1990-01-18

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