AU6742581A - Process and intermediates for 6,7-dihydro-9-fluoro-5-methyl- 1-oxo-1h,5h-benzo(ij) quinolizine-2-carboxylic acid - Google Patents

Process and intermediates for 6,7-dihydro-9-fluoro-5-methyl- 1-oxo-1h,5h-benzo(ij) quinolizine-2-carboxylic acid

Info

Publication number
AU6742581A
AU6742581A AU67425/81A AU6742581A AU6742581A AU 6742581 A AU6742581 A AU 6742581A AU 67425/81 A AU67425/81 A AU 67425/81A AU 6742581 A AU6742581 A AU 6742581A AU 6742581 A AU6742581 A AU 6742581A
Authority
AU
Australia
Prior art keywords
quinolizine
benzo
dihydro
intermediates
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU67425/81A
Other versions
AU524459B2 (en
Inventor
Kirk Gustav Hedberg
Joel Raymond Jacobson
Charles Martin Leir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ceva Sante Animale SA
Original Assignee
Elf Sanofi SA
Sanofi Sante Nutrition Animale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/122,599 external-priority patent/US4301288A/en
Priority claimed from US06/122,470 external-priority patent/US4301291A/en
Priority claimed from US06/122,657 external-priority patent/US4301289A/en
Application filed by Elf Sanofi SA, Sanofi Sante Nutrition Animale filed Critical Elf Sanofi SA
Publication of AU6742581A publication Critical patent/AU6742581A/en
Application granted granted Critical
Publication of AU524459B2 publication Critical patent/AU524459B2/en
Assigned to SANOFI SANTE NUTRITION ANIMALE reassignment SANOFI SANTE NUTRITION ANIMALE Alteration of Name(s) in Register under S187 Assignors: RIKER LABORATORIES, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU67425/81A 1980-02-19 1981-02-18 Process and intermediates for 6,7-dihydro-9-fluoro-5-methyl- 1-oxo-1h,5h-benzo(ij) quinolizine-2-carboxylic acid Ceased AU524459B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US122470 1980-02-19
US122599 1980-02-19
US06/122,599 US4301288A (en) 1980-02-19 1980-02-19 Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid
US122657 1980-02-19
US06/122,470 US4301291A (en) 1980-02-19 1980-02-19 Intermediates for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid
US06/122,657 US4301289A (en) 1980-02-19 1980-02-19 Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid

Publications (2)

Publication Number Publication Date
AU6742581A true AU6742581A (en) 1981-09-24
AU524459B2 AU524459B2 (en) 1982-09-16

Family

ID=27382802

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67425/81A Ceased AU524459B2 (en) 1980-02-19 1981-02-18 Process and intermediates for 6,7-dihydro-9-fluoro-5-methyl- 1-oxo-1h,5h-benzo(ij) quinolizine-2-carboxylic acid

Country Status (6)

Country Link
JP (2) JPH0215077A (en)
AU (1) AU524459B2 (en)
FR (1) FR2476079A1 (en)
GB (1) GB2069498B (en)
IE (1) IE50928B1 (en)
NZ (1) NZ196293A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400386A (en) * 1981-11-06 1983-08-23 Riker Laboratories, Inc. Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine
US4472407A (en) * 1983-03-17 1984-09-18 Riker Laboratories, Inc. Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu
DE3413693A1 (en) * 1984-04-11 1985-10-17 Boehringer Mannheim Gmbh, 6800 Mannheim FLUORINATED ANILINE DERIVATIVES AND THEIR USE
IT1231425B (en) * 1987-10-05 1991-12-04 Prodotti Antibiotici Spa PROCEDURE FOR THE SYNTHESIS OF A BENZO (IJ) QUINOLIZIN-2-CARBOXYLIC ACID DERIVATIVE
CA2009664A1 (en) * 1989-02-27 1990-08-27 Philip Thiam Shin Lau Tetrahydroquinolines and method of preparation
US5043469A (en) * 1989-07-17 1991-08-27 Eastman Kodak Company Process for preparing 5-substituted aminophenols
CA2422137A1 (en) 2000-09-14 2003-03-13 Kaken Pharmaceutical Co., Ltd. Tetrahydroquinoline compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793524A (en) * 1971-12-30 1973-06-29 Riker Laboratories Inc BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES
ZA728444B (en) * 1971-12-30 1973-10-31 Riker Laboratories Inc Substituted benzo(ij)quinolizine-2-carboxylic acids and derivatives thereof

Also Published As

Publication number Publication date
JPH0416474B2 (en) 1992-03-24
NZ196293A (en) 1983-09-02
FR2476079B1 (en) 1984-04-20
FR2476079A1 (en) 1981-08-21
JPH0375541B2 (en) 1991-12-02
IE810326L (en) 1981-08-19
AU524459B2 (en) 1982-09-16
GB2069498A (en) 1981-08-26
JPH0215066A (en) 1990-01-18
JPH0215077A (en) 1990-01-18
GB2069498B (en) 1984-02-08
IE50928B1 (en) 1986-08-20

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