GB2069498B - Substituted tetrahydroquinaldines intermediates for 6,7-dihydro-9-flouro-5-methyl-oxo-1h,5h-benzo(ij)quinolizine-2-carboxylic acid - Google Patents
Substituted tetrahydroquinaldines intermediates for 6,7-dihydro-9-flouro-5-methyl-oxo-1h,5h-benzo(ij)quinolizine-2-carboxylic acidInfo
- Publication number
- GB2069498B GB2069498B GB8105054A GB8105054A GB2069498B GB 2069498 B GB2069498 B GB 2069498B GB 8105054 A GB8105054 A GB 8105054A GB 8105054 A GB8105054 A GB 8105054A GB 2069498 B GB2069498 B GB 2069498B
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydroquinaldines
- flouro
- quinolizine
- benzo
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/122,470 US4301291A (en) | 1980-02-19 | 1980-02-19 | Intermediates for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid |
| US06/122,657 US4301289A (en) | 1980-02-19 | 1980-02-19 | Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid |
| US06/122,599 US4301288A (en) | 1980-02-19 | 1980-02-19 | Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2069498A GB2069498A (en) | 1981-08-26 |
| GB2069498B true GB2069498B (en) | 1984-02-08 |
Family
ID=27382802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8105054A Expired GB2069498B (en) | 1980-02-19 | 1981-02-18 | Substituted tetrahydroquinaldines intermediates for 6,7-dihydro-9-flouro-5-methyl-oxo-1h,5h-benzo(ij)quinolizine-2-carboxylic acid |
Country Status (6)
| Country | Link |
|---|---|
| JP (2) | JPH0215077A (en) |
| AU (1) | AU524459B2 (en) |
| FR (1) | FR2476079A1 (en) |
| GB (1) | GB2069498B (en) |
| IE (1) | IE50928B1 (en) |
| NZ (1) | NZ196293A (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4400386A (en) * | 1981-11-06 | 1983-08-23 | Riker Laboratories, Inc. | Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine |
| US4472407A (en) * | 1983-03-17 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu |
| DE3413693A1 (en) * | 1984-04-11 | 1985-10-17 | Boehringer Mannheim Gmbh, 6800 Mannheim | FLUORINATED ANILINE DERIVATIVES AND THEIR USE |
| IT1231425B (en) * | 1987-10-05 | 1991-12-04 | Prodotti Antibiotici Spa | PROCEDURE FOR THE SYNTHESIS OF A BENZO (IJ) QUINOLIZIN-2-CARBOXYLIC ACID DERIVATIVE |
| CA2009664A1 (en) * | 1989-02-27 | 1990-08-27 | Philip Thiam Shin Lau | Tetrahydroquinolines and method of preparation |
| US5043469A (en) * | 1989-07-17 | 1991-08-27 | Eastman Kodak Company | Process for preparing 5-substituted aminophenols |
| CA2422137A1 (en) * | 2000-09-14 | 2003-03-13 | Kaken Pharmaceutical Co., Ltd. | Tetrahydroquinoline compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793524A (en) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES |
| ZA728444B (en) * | 1971-12-30 | 1973-10-31 | Riker Laboratories Inc | Substituted benzo(ij)quinolizine-2-carboxylic acids and derivatives thereof |
-
1981
- 1981-02-18 IE IE326/81A patent/IE50928B1/en not_active IP Right Cessation
- 1981-02-18 GB GB8105054A patent/GB2069498B/en not_active Expired
- 1981-02-18 NZ NZ196293A patent/NZ196293A/en unknown
- 1981-02-18 FR FR8103180A patent/FR2476079A1/en active Granted
- 1981-02-18 AU AU67425/81A patent/AU524459B2/en not_active Ceased
-
1989
- 1989-05-01 JP JP1112746A patent/JPH0215077A/en active Granted
- 1989-05-01 JP JP1112745A patent/JPH0215066A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NZ196293A (en) | 1983-09-02 |
| JPH0375541B2 (en) | 1991-12-02 |
| GB2069498A (en) | 1981-08-26 |
| FR2476079A1 (en) | 1981-08-21 |
| FR2476079B1 (en) | 1984-04-20 |
| AU524459B2 (en) | 1982-09-16 |
| AU6742581A (en) | 1981-09-24 |
| IE50928B1 (en) | 1986-08-20 |
| JPH0416474B2 (en) | 1992-03-24 |
| JPH0215077A (en) | 1990-01-18 |
| JPH0215066A (en) | 1990-01-18 |
| IE810326L (en) | 1981-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19980218 |