NZ189151A - Peptide derivatives of phosphonic acid and pharmaceutical compositions - Google Patents

Peptide derivatives of phosphonic acid and pharmaceutical compositions

Info

Publication number
NZ189151A
NZ189151A NZ189151A NZ18915178A NZ189151A NZ 189151 A NZ189151 A NZ 189151A NZ 189151 A NZ189151 A NZ 189151A NZ 18915178 A NZ18915178 A NZ 18915178A NZ 189151 A NZ189151 A NZ 189151A
Authority
NZ
New Zealand
Prior art keywords
pharmaceutical compositions
phosphonic acid
peptide derivatives
peptide
derivatives
Prior art date
Application number
NZ189151A
Inventor
C H Hassall
F R Atherton
P S Ringrose
M J Hall
R W Lambert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ189151A publication Critical patent/NZ189151A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ189151A 1977-12-20 1978-12-12 Peptide derivatives of phosphonic acid and pharmaceutical compositions NZ189151A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5293877 1977-12-20
GB7842727 1978-11-01

Publications (1)

Publication Number Publication Date
NZ189151A true NZ189151A (en) 1981-05-15

Family

ID=26267167

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ189151A NZ189151A (en) 1977-12-20 1978-12-12 Peptide derivatives of phosphonic acid and pharmaceutical compositions

Country Status (23)

Country Link
EP (1) EP0002534B1 (en)
JP (1) JPS5492921A (en)
AT (1) AT366057B (en)
AU (1) AU4248378A (en)
BR (1) BR7808342A (en)
CS (1) CS211394B2 (en)
CU (1) CU35001A (en)
DE (2) DE2854292A1 (en)
DK (1) DK536578A (en)
ES (1) ES476124A1 (en)
FI (1) FI783886A (en)
FR (1) FR2450260A1 (en)
GR (1) GR73085B (en)
IL (1) IL56208A0 (en)
IT (1) IT1102401B (en)
LU (1) LU80671A1 (en)
MC (1) MC1242A1 (en)
NL (1) NL7812311A (en)
NO (1) NO784285L (en)
NZ (1) NZ189151A (en)
PT (1) PT68938A (en)
SE (1) SE7813069L (en)
ZA (1) ZA786976B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1307787C (en) * 1986-06-11 1992-09-22 Melanie J. Loots Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors
CN110156640A (en) * 2019-06-14 2019-08-23 南京博源医药科技有限公司 A kind of preparation process of N- benzyloxycarbonyl-amino acid
CN110143896A (en) * 2019-06-14 2019-08-20 南京博源医药科技有限公司 A kind of preparation method of N- benzyloxycarbonyl group-L- glycoleucine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1081511B (en) * 1976-07-13 1985-05-21 Hoffmann La Roche PEPTIDE DERIVATIVES AND THEIR PREPARATION
DE2632188A1 (en) * 1976-07-16 1978-01-26 Hoffmann La Roche Potentiated antibiotic compsns. - contg. peptide phosphonic or phosphinic acids
GB1585275A (en) * 1976-07-21 1981-02-25 Roche Products Ltd Peptide derivatives of phosphonic and phosphinic acids

Also Published As

Publication number Publication date
DE2854292A1 (en) 1979-07-05
IT1102401B (en) 1985-10-07
AU4248378A (en) 1979-06-28
ES476124A1 (en) 1980-07-16
EP0002534A1 (en) 1979-06-27
ATA904178A (en) 1981-07-15
EP0002534B1 (en) 1982-01-13
CU35001A (en) 1981-12-04
FI783886A (en) 1979-06-21
NL7812311A (en) 1979-06-22
AT366057B (en) 1982-03-10
JPS5492921A (en) 1979-07-23
ZA786976B (en) 1980-07-30
IL56208A0 (en) 1979-03-12
FR2450260A1 (en) 1980-09-26
DK536578A (en) 1979-06-21
SE7813069L (en) 1979-06-21
IT7831023A0 (en) 1978-12-19
GR73085B (en) 1984-01-31
CS211394B2 (en) 1982-02-26
MC1242A1 (en) 1979-10-26
LU80671A1 (en) 1980-01-22
BR7808342A (en) 1979-08-07
NO784285L (en) 1979-06-21
DE2861537D1 (en) 1982-02-25
PT68938A (en) 1979-01-01

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