NZ185909A - 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions - Google Patents

1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions

Info

Publication number
NZ185909A
NZ185909A NZ185909A NZ18590977A NZ185909A NZ 185909 A NZ185909 A NZ 185909A NZ 185909 A NZ185909 A NZ 185909A NZ 18590977 A NZ18590977 A NZ 18590977A NZ 185909 A NZ185909 A NZ 185909A
Authority
NZ
New Zealand
Prior art keywords
pharmaxeutical
hydantois
dusubstituted
thiohydantoins
compositions
Prior art date
Application number
NZ185909A
Other languages
English (en)
Inventor
G Wootton
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB52955/76A external-priority patent/GB1598662A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of NZ185909A publication Critical patent/NZ185909A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ185909A 1976-12-18 1977-12-08 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions NZ185909A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB52955/76A GB1598662A (en) 1976-12-18 1976-12-18 10,12-diazoprostaglandins
GB3036977 1977-07-20

Publications (1)

Publication Number Publication Date
NZ185909A true NZ185909A (en) 1980-11-14

Family

ID=26260409

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ185909A NZ185909A (en) 1976-12-18 1977-12-08 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions

Country Status (15)

Country Link
JP (1) JPS5382779A (de)
AT (1) AT368498B (de)
AU (1) AU514523B2 (de)
CH (1) CH639076A5 (de)
DE (1) DE2755771A1 (de)
DK (1) DK551777A (de)
ES (1) ES465176A1 (de)
FI (1) FI773812A (de)
FR (1) FR2374309A1 (de)
IL (1) IL53559A0 (de)
NL (1) NL7713971A (de)
NO (1) NO774348L (de)
NZ (1) NZ185909A (de)
PH (1) PH14398A (de)
SE (1) SE7714373L (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
DK543178A (da) * 1977-12-01 1979-06-02 Wellcome Found Thiodydantoinderivater
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (de) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
EP0007180B1 (de) * 1978-06-15 1983-03-30 Beecham Group Plc Prostaglandinanaloge Triazolderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
EP0006352A1 (de) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoine und Thiohydantoine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
JPS55151569A (en) * 1979-05-09 1980-11-26 Wellcome Found Optically active heterocyclic compounds* their synthesis and medical blend containing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323193A1 (de) 1972-05-10 1973-11-22 Du Pont Pyrazolidinone
FR2258376A1 (en) 1974-01-21 1975-08-18 Aries Robert 10-Aza prostaglandins - for treatment of blood pressure and gastro-intestinal disorders and in prepn for confinement
GB1524818A (en) 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
FR2374309B1 (de) 1980-05-16
ES465176A1 (es) 1979-01-01
NO774348L (no) 1978-06-20
SE7714373L (sv) 1978-06-19
DE2755771A1 (de) 1978-06-29
JPS5382779A (en) 1978-07-21
ATA893777A (de) 1982-02-15
AU514523B2 (en) 1981-02-12
DK551777A (da) 1978-06-19
IL53559A0 (en) 1978-03-10
AU3161377A (en) 1979-06-21
PH14398A (en) 1981-06-25
CH639076A5 (en) 1983-10-31
FR2374309A1 (fr) 1978-07-13
FI773812A (fi) 1978-06-19
AT368498B (de) 1982-10-11
NL7713971A (nl) 1978-06-20

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