NO995822D0 - Sulfate salt of an HIV protease inhibitor which has improved oral absorption and bioavailability - Google Patents

Sulfate salt of an HIV protease inhibitor which has improved oral absorption and bioavailability

Info

Publication number
NO995822D0
NO995822D0 NO995822A NO995822A NO995822D0 NO 995822 D0 NO995822 D0 NO 995822D0 NO 995822 A NO995822 A NO 995822A NO 995822 A NO995822 A NO 995822A NO 995822 D0 NO995822 D0 NO 995822D0
Authority
NO
Norway
Prior art keywords
bioavailability
protease inhibitor
hiv protease
sulfate salt
oral absorption
Prior art date
Application number
NO995822A
Other languages
Norwegian (no)
Other versions
NO995822L (en
Inventor
David Askin
R Scott Hoerrner
Robert M Purick
Paul Reider
Richard J Varsolona
Ralph P Volante
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9714320.0A external-priority patent/GB9714320D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO995822D0 publication Critical patent/NO995822D0/en
Publication of NO995822L publication Critical patent/NO995822L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO995822A 1997-05-29 1999-11-26 Sulfate salt of an HIV protease inhibitor which has improved oral absorption and bioavailability NO995822L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4795097P 1997-05-29 1997-05-29
GBGB9714320.0A GB9714320D0 (en) 1997-07-07 1997-07-07 Hiv protease inhibitor
PCT/US1998/010633 WO1998054178A1 (en) 1997-05-29 1998-05-26 Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability

Publications (2)

Publication Number Publication Date
NO995822D0 true NO995822D0 (en) 1999-11-26
NO995822L NO995822L (en) 2000-01-28

Family

ID=26311845

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995822A NO995822L (en) 1997-05-29 1999-11-26 Sulfate salt of an HIV protease inhibitor which has improved oral absorption and bioavailability

Country Status (22)

Country Link
EP (1) EP0986554A1 (en)
JP (1) JP3267632B2 (en)
KR (1) KR20010013042A (en)
CN (1) CN1257497A (en)
AU (1) AU730245B2 (en)
BG (1) BG103923A (en)
BR (1) BR9809498A (en)
CA (1) CA2291086A1 (en)
EA (1) EA199901095A1 (en)
EE (1) EE9900543A (en)
HR (1) HRP980283A2 (en)
HU (1) HUP0004621A3 (en)
ID (1) ID23858A (en)
IL (1) IL132779A0 (en)
IS (1) IS5240A (en)
NO (1) NO995822L (en)
PE (1) PE75099A1 (en)
PL (1) PL336847A1 (en)
SK (1) SK163299A3 (en)
TR (1) TR199902816T2 (en)
TW (1) TW438799B (en)
WO (1) WO1998054178A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003514910A (en) 1999-11-24 2003-04-22 メルク エンド カムパニー インコーポレーテッド Gamma-hydroxy-2- (fluoroalkylaminocarbonyl) -1-piperazinepentanamides as HIV protease inhibitors
US20020082421A1 (en) * 2000-09-14 2002-06-27 Abdel-Magid Ahmed F. Novel solid salt forms of N-[2-[4-[2-(1- methylethoxy)phenyl]-1-piperazinyl]-2-oxo-1piperidineacetamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0734387B1 (en) * 1993-12-15 2002-04-10 Merck & Co. Inc. Hiv protease inhibitors

Also Published As

Publication number Publication date
EP0986554A1 (en) 2000-03-22
KR20010013042A (en) 2001-02-26
HRP980283A2 (en) 1999-08-31
BG103923A (en) 2000-06-30
IS5240A (en) 1999-11-09
HUP0004621A3 (en) 2002-04-29
EA199901095A1 (en) 2000-08-28
EE9900543A (en) 2000-06-15
AU7595998A (en) 1998-12-30
WO1998054178A1 (en) 1998-12-03
CN1257497A (en) 2000-06-21
IL132779A0 (en) 2001-03-19
JP3267632B2 (en) 2002-03-18
NO995822L (en) 2000-01-28
TR199902816T2 (en) 2000-02-21
JP2000513747A (en) 2000-10-17
TW438799B (en) 2001-06-07
CA2291086A1 (en) 1998-12-03
ID23858A (en) 2000-05-25
SK163299A3 (en) 2000-07-11
PL336847A1 (en) 2000-07-17
PE75099A1 (en) 1999-08-11
BR9809498A (en) 2000-06-20
HUP0004621A2 (en) 2002-03-28
AU730245B2 (en) 2001-03-01

Similar Documents

Publication Publication Date Title
EE04434B1 (en) Bisulfate salt of HIV protease inhibitor
PT1086076E (en) SULFONAMIDE INHIBITORS OF ASPARTIL PROTEASE
DK1070069T3 (en) Bicyclic hydroxamic acid derivatives
IS5340A (en) Aryloxyarylsulfonylamino hydroxamic acid derivatives
DE60101968D1 (en) ALPHA CRYSTAL SHAPE OF PERINDOPRILE TERT BUTYLAMINE SALT
NO993587D0 (en) Sulfonamide metalloprotease inhibitors
NO20011886L (en) Forms of fexofenadine
ATE230275T1 (en) ANGIOGENSIS INHIBITOR
NO974403D0 (en) Reversible protease inhibitors
PT1047450E (en) ACE INHIBITOR COMBINATIONS - MMP INHIBITOR
FI962073A0 (en) Prodrug forms of the HIV protease inhibitor
FI20000194A0 (en) The method of trading
EE04750B1 (en) Method for the preparation of HIV protease inhibitors
DE69908951D1 (en) CRYSTAL FORMS OF OSANETANT
NO995822D0 (en) Sulfate salt of an HIV protease inhibitor which has improved oral absorption and bioavailability
EE200100084A (en) New pharmaceutical uses of NOS inhibitors
DE29800292U1 (en) Trinket
DE29712586U1 (en) Trinket
DE29818455U1 (en) Trinket
DE29806370U1 (en) Trinket
DE29723230U1 (en) Trinket
DE29723217U1 (en) Trinket
DE29722096U1 (en) Trinket
ID20888A (en) YEARS OF ORGANOLOGICAL PLABETIZATION
NO994415D0 (en) HIV protease inhibitors

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application