NO994304L - Fremgangsmåte for fremstilling av 2-tienyletylamin-derivater - Google Patents
Fremgangsmåte for fremstilling av 2-tienyletylamin-derivaterInfo
- Publication number
- NO994304L NO994304L NO994304A NO994304A NO994304L NO 994304 L NO994304 L NO 994304L NO 994304 A NO994304 A NO 994304A NO 994304 A NO994304 A NO 994304A NO 994304 L NO994304 L NO 994304L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- general formula
- alkali metal
- metal atom
- date sep
- Prior art date
Links
- HVLUYXIJZLDNIS-UHFFFAOYSA-N 2-thiophen-2-ylethanamine Chemical class NCCC1=CC=CS1 HVLUYXIJZLDNIS-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 3
- 150000001340 alkali metals Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001732 carboxylic acid derivatives Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical group 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- -1 phenylglycine ester Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9702621A FR2760456B1 (fr) | 1997-03-05 | 1997-03-05 | Procede de preparation de derives de 2-thienyl-ethylamine |
PCT/FR1998/000441 WO1998039322A1 (fr) | 1997-03-05 | 1998-03-05 | Procede de preparation de derives de 2-thienylethylamine |
Publications (3)
Publication Number | Publication Date |
---|---|
NO994304D0 NO994304D0 (no) | 1999-09-03 |
NO994304L true NO994304L (no) | 1999-11-03 |
NO323613B1 NO323613B1 (no) | 2007-06-18 |
Family
ID=9504438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19994304A NO323613B1 (no) | 1997-03-05 | 1999-09-03 | Fremgangsmate for fremstilling av 2-tienyletylamin-derivater |
Country Status (12)
Country | Link |
---|---|
US (1) | US6080875A (no) |
EP (1) | EP0971915B1 (no) |
JP (1) | JP4283896B2 (no) |
AT (1) | ATE240311T1 (no) |
AU (1) | AU6839498A (no) |
BR (1) | BR9808174B1 (no) |
CA (1) | CA2283126C (no) |
DE (1) | DE69814608T2 (no) |
ES (1) | ES2200332T3 (no) |
FR (1) | FR2760456B1 (no) |
NO (1) | NO323613B1 (no) |
WO (1) | WO1998039322A1 (no) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495691B1 (en) | 2001-07-06 | 2002-12-17 | Brantford Chemicals Inc. | Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives |
US6767913B2 (en) | 2001-12-18 | 2004-07-27 | Teva Pharmaceutical Industries Ltd. | Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms |
US7074928B2 (en) | 2002-01-11 | 2006-07-11 | Teva Pharmaceutical Industries, Ltd. | Polymorphs of clopidogrel hydrogensulfate |
IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
US6800759B2 (en) * | 2002-08-02 | 2004-10-05 | Teva Pharmaceutical Industries Ltd. | Racemization and enantiomer separation of clopidogrel |
WO2004081015A1 (en) * | 2003-03-10 | 2004-09-23 | Hetero Drugs Limited | Amorphous clopidogrel hydrogen sulfate |
EP1603920A1 (en) | 2003-03-12 | 2005-12-14 | Cadila Healthcare Ltd. | Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate |
US8907090B2 (en) | 2003-11-03 | 2014-12-09 | Cadila Healthcare Limited | Processes for preparing different forms of (S)-(+)-Clopidogrel bisulfate |
WO2006003671A1 (en) * | 2004-07-02 | 2006-01-12 | Srinivasa Reddy Battula | A process for resolution of methylamino(2-chlorophenyl)acetate |
US20060154957A1 (en) * | 2004-09-21 | 2006-07-13 | Nina Finkelstein | Crystalline clopidogrel hydrobromide and processes for preparation thereof |
EP1851231A2 (en) * | 2005-02-24 | 2007-11-07 | Teva Pharmaceutical Industries Ltd | Clopidogrel base suitable for pharmaceutical formulation and preparation thereof |
EP1931682A2 (en) * | 2006-08-03 | 2008-06-18 | Teva Pharmaceutical Industries Ltd. | Process for preparing clopidogrel bisulphate |
EP1980563A1 (en) | 2007-04-09 | 2008-10-15 | BATTULA, Srinivasa Reddy | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate |
KR20090086903A (ko) * | 2007-04-18 | 2009-08-14 | 테바 파마슈티컬 인더스트리즈 리미티드 | 개선된 클로피도그렐의 제조 방법 |
EP2107061A1 (en) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
US20090264460A1 (en) * | 2008-04-21 | 2009-10-22 | Mamta Mishra | Clopidogrel pharmaceutical formulations |
KR100990949B1 (ko) * | 2008-06-09 | 2010-10-29 | 엔자이텍 주식회사 | 클로피도그렐 및 그의 유도체의 제조방법 |
WO2010046476A1 (en) * | 2008-10-24 | 2010-04-29 | Sandoz Ag | A process for the preparation of s-clopidogrel |
US8563690B2 (en) * | 2008-11-03 | 2013-10-22 | The Board Of Trustees Of The University Of Illinois | Modulation of platelet aggregation |
WO2012123958A1 (en) | 2011-02-14 | 2012-09-20 | Cadila Healthcare Limited | Highly pure salts of clopidogrel free of genotoxic impurities |
CN103172527A (zh) * | 2011-12-26 | 2013-06-26 | 湖北德洲科技发展有限公司 | 一种制备氯吡格雷合成中间体-邻氯苯甘氨酸甲酯的方法 |
SI2874625T1 (sl) * | 2012-07-17 | 2017-10-30 | Sanofi | Uporaba inhibitorjev VEGFR-3 za zdravljenje hepatoceličnega karcinoma |
CN106748853B (zh) * | 2016-11-25 | 2018-12-28 | 河南普瑞医药科技有限公司 | 一种(s)-邻氯苯甘氨酸甲酯盐酸盐的制备方法 |
CN115784914B (zh) * | 2022-12-20 | 2023-05-12 | 石家庄中硕科技有限公司 | 一种邻氯苯甘氨酸的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0355170A4 (en) * | 1986-04-24 | 1990-09-05 | N-Proizv Mekh Robot Truda Sover | Vertical centrifugal casting machine |
FR2624860B1 (fr) * | 1987-12-18 | 1990-06-01 | Sanofi Sa | Procede de preparation de la n-(chloro-2 benzyl) (thienyl-2)-2 ethylamine |
AR245119A1 (es) * | 1988-08-22 | 1993-12-30 | Merrell Dow Pharma | Procedimiento para preparar un grupo de fenilalquiltiofenos que estan sustituidos adicionalmente con un grupo acido tiadicarboxilico. |
FR2664276B1 (fr) * | 1990-07-04 | 1992-10-23 | Sanofi Sa | Derive thienyl-2 glycidique, son procede de preparation et son utilisation comme intermediaire de synthese. |
FR2664596B1 (fr) * | 1990-07-10 | 1994-06-10 | Sanofi Sa | Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese. |
-
1997
- 1997-03-05 FR FR9702621A patent/FR2760456B1/fr not_active Expired - Fee Related
-
1998
- 1998-03-05 DE DE69814608T patent/DE69814608T2/de not_active Expired - Lifetime
- 1998-03-05 AU AU68394/98A patent/AU6839498A/en not_active Abandoned
- 1998-03-05 EP EP98913841A patent/EP0971915B1/fr not_active Expired - Lifetime
- 1998-03-05 US US09/380,450 patent/US6080875A/en not_active Expired - Lifetime
- 1998-03-05 WO PCT/FR1998/000441 patent/WO1998039322A1/fr active IP Right Grant
- 1998-03-05 JP JP53824098A patent/JP4283896B2/ja not_active Expired - Fee Related
- 1998-03-05 CA CA002283126A patent/CA2283126C/fr not_active Expired - Fee Related
- 1998-03-05 BR BRPI9808174-8A patent/BR9808174B1/pt not_active IP Right Cessation
- 1998-03-05 ES ES98913841T patent/ES2200332T3/es not_active Expired - Lifetime
- 1998-03-05 AT AT98913841T patent/ATE240311T1/de not_active IP Right Cessation
-
1999
- 1999-09-03 NO NO19994304A patent/NO323613B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1998039322A1 (fr) | 1998-09-11 |
ES2200332T3 (es) | 2004-03-01 |
EP0971915A1 (fr) | 2000-01-19 |
JP4283896B2 (ja) | 2009-06-24 |
US6080875A (en) | 2000-06-27 |
CA2283126C (fr) | 2008-09-02 |
AU6839498A (en) | 1998-09-22 |
BR9808174A (pt) | 2000-05-16 |
FR2760456A1 (fr) | 1998-09-11 |
JP2001513806A (ja) | 2001-09-04 |
NO323613B1 (no) | 2007-06-18 |
CA2283126A1 (fr) | 1998-09-11 |
DE69814608T2 (de) | 2004-04-01 |
DE69814608D1 (de) | 2003-06-18 |
FR2760456B1 (fr) | 2000-05-12 |
NO994304D0 (no) | 1999-09-03 |
EP0971915B1 (fr) | 2003-05-14 |
BR9808174B1 (pt) | 2010-06-29 |
ATE240311T1 (de) | 2003-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |