NO992609L - Syndecan forsterkerelement og dets anvendelse til Õ mÕlrette genekspresjon - Google Patents

Syndecan forsterkerelement og dets anvendelse til Õ mÕlrette genekspresjon

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Publication number
NO992609L
NO992609L NO992609A NO992609A NO992609L NO 992609 L NO992609 L NO 992609L NO 992609 A NO992609 A NO 992609A NO 992609 A NO992609 A NO 992609A NO 992609 L NO992609 L NO 992609L
Authority
NO
Norway
Prior art keywords
syndecan
gene expression
amplifier element
targeted gene
enhancer element
Prior art date
Application number
NO992609A
Other languages
English (en)
Other versions
NO992609D0 (no
Inventor
Markku Jalkanen
Panu Jaakkola
Tapani Vihinen
Original Assignee
Biotie Therapies Ltd Oy
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25059389&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO992609(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotie Therapies Ltd Oy filed Critical Biotie Therapies Ltd Oy
Publication of NO992609D0 publication Critical patent/NO992609D0/no
Publication of NO992609L publication Critical patent/NO992609L/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/30Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Det er beskrevet et syndecanforsterkerelement, nye proteiner som aktiverer forsterkerelementet, ikke-humane transgene dyr som omfatter dette forsterkerelementet koblet til et strukturelt gen og anvendelse av dette forsterkerelement for å regulere ekspresjon av syndecan og andre gener er også tilveiebragt. Forsterkerelementet kan også anvendes til å målrette ekspresjon av et gen til sårsteder.
NO992609A 1996-12-02 1999-05-31 Syndecan forsterkerelement og dets anvendelse til Õ mÕlrette genekspresjon NO992609L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/760,534 US6017727A (en) 1994-03-07 1996-12-02 Syndecan enhancer element and syndecan stimulation of cellular differentiation
PCT/FI1997/000748 WO1998024921A1 (en) 1996-12-02 1997-12-02 Syndecan enhancer element and its use for targeting gene expression

Publications (2)

Publication Number Publication Date
NO992609D0 NO992609D0 (no) 1999-05-31
NO992609L true NO992609L (no) 1999-05-31

Family

ID=25059389

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992609A NO992609L (no) 1996-12-02 1999-05-31 Syndecan forsterkerelement og dets anvendelse til Õ mÕlrette genekspresjon

Country Status (10)

Country Link
US (1) US6017727A (no)
EP (1) EP0941354A1 (no)
JP (1) JP2001505429A (no)
KR (1) KR20000057361A (no)
AU (1) AU731765B2 (no)
CA (1) CA2272851A1 (no)
HU (1) HUP0001152A3 (no)
NO (1) NO992609L (no)
NZ (1) NZ335328A (no)
WO (1) WO1998024921A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492344B1 (en) 1993-12-01 2002-12-10 Biotie Therapies Corp. Syndecan enhancer element and syndecan stimulation of cellular differentiation
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
WO2009105624A2 (en) * 2008-02-21 2009-08-27 Massachusetts Institute Of Technology Simultaneous delivery of receptors and/or co-receptors for growth factor stability and activity
WO2021150987A1 (en) * 2020-01-22 2021-07-29 Altius Institute For Biomedical Sciences Novel erythroid specific enhancers and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806893D0 (en) * 1988-03-23 1988-04-27 Unilever Plc Cosmetic composition
WO1990012033A1 (en) * 1989-03-29 1990-10-18 The Board Of Trustees Of The Leland Stanford Junior University Construction and use of synthetic constructs encoding syndecan
JPH04224522A (ja) * 1990-04-27 1992-08-13 Merck & Co Inc 繊維芽細胞増殖因子含有組成物による禿頭症の治療又は予防方法
US5147854A (en) * 1990-05-22 1992-09-15 Hoffmann-La Roche Inc. Tgf-b compositions and method
KR0162670B1 (ko) * 1991-01-15 1999-05-01 마르쿠 잘카넨 세포의 악성 전형을 나타내기 위한 조직 및 체액과 같은 생물학적 물질에서의 신데칸 내용물의 검출
WO1993005167A1 (en) * 1991-09-06 1993-03-18 Children's Medical Center Corporation Cell-type specific heparan sulfate proteoglycans and their uses
US5726058A (en) * 1992-12-01 1998-03-10 Jalkanen; Markku Syndecan stimulation of cellular differentiation
ES2154290T3 (es) * 1992-12-01 2001-04-01 Biotie Therapies Corp Estimulacion de la diferenciacion celular por sindecano.

Also Published As

Publication number Publication date
NO992609D0 (no) 1999-05-31
HUP0001152A3 (en) 2001-09-28
CA2272851A1 (en) 1998-06-11
EP0941354A1 (en) 1999-09-15
JP2001505429A (ja) 2001-04-24
NZ335328A (en) 2000-09-29
HUP0001152A2 (en) 2000-07-28
US6017727A (en) 2000-01-25
KR20000057361A (ko) 2000-09-15
AU731765B2 (en) 2001-04-05
WO1998024921A1 (en) 1998-06-11
AU5222598A (en) 1998-06-29

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