ATE323757T1 - Im irak-gen modifizierte transgene mäuse - Google Patents
Im irak-gen modifizierte transgene mäuseInfo
- Publication number
- ATE323757T1 ATE323757T1 AT99921917T AT99921917T ATE323757T1 AT E323757 T1 ATE323757 T1 AT E323757T1 AT 99921917 T AT99921917 T AT 99921917T AT 99921917 T AT99921917 T AT 99921917T AT E323757 T1 ATE323757 T1 AT E323757T1
- Authority
- AT
- Austria
- Prior art keywords
- iraq
- transgenic mice
- gene modified
- modified transgenic
- gene
- Prior art date
Links
- 241000699660 Mus musculus Species 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000011830 transgenic mouse model Methods 0.000 title 1
- 101710199015 Interleukin-1 receptor-associated kinase 1 Proteins 0.000 abstract 4
- 241001465754 Metazoa Species 0.000 abstract 4
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 102100036342 Interleukin-1 receptor-associated kinase 1 Human genes 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0368—Animal model for inflammation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8557098P | 1998-05-15 | 1998-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE323757T1 true ATE323757T1 (de) | 2006-05-15 |
Family
ID=22192507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99921917T ATE323757T1 (de) | 1998-05-15 | 1999-05-13 | Im irak-gen modifizierte transgene mäuse |
Country Status (9)
Country | Link |
---|---|
US (1) | US6166289A (de) |
EP (1) | EP1082408B1 (de) |
AT (1) | ATE323757T1 (de) |
AU (1) | AU769734B2 (de) |
CA (1) | CA2328591A1 (de) |
DE (1) | DE69930932T2 (de) |
DK (1) | DK1082408T3 (de) |
ES (1) | ES2262321T3 (de) |
WO (1) | WO1999060100A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6818419B2 (en) * | 2000-01-13 | 2004-11-16 | Tularik Inc. | IRAK-4: compositions and methods of use |
AU2002228968A1 (en) * | 2000-12-13 | 2002-06-24 | Deltagen, Inc. | Transgenic mice containing serine/threonine kinase (stk) target gene disruptions |
US20030228690A1 (en) * | 2002-06-10 | 2003-12-11 | Isis Pharmaceuticals Inc. | Antisense modulation of IL-1 receptor-associated kinase-1 expression |
EP1482030A1 (de) * | 2003-05-28 | 2004-12-01 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Methode zur Erhöhung des Ertrags an proliferierenden primären Keratinozyten |
WO2005001087A2 (en) | 2003-06-11 | 2005-01-06 | Regeneron Pharmaceuticals, Inc. | Methods of modifying genes in eukaryotic cells |
WO2006017621A2 (en) * | 2004-08-02 | 2006-02-16 | Janssen Pharmaceutica N.V. | IRAK1c SPLICE VARIANT AND ITS USE |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5654397A (en) * | 1985-06-23 | 1997-08-05 | Tularik, Inc. | Interleukin-1 receptor-associated protein kinase and assays |
US5569824A (en) * | 1991-01-04 | 1996-10-29 | Baylor College Of Medicine | Transgenic mice containing a disrupted p53 gene |
GB9100481D0 (en) * | 1991-01-10 | 1991-02-20 | Inst Nat Sante Rech Med | Genetically engineered mice |
US5604102A (en) * | 1992-04-15 | 1997-02-18 | Athena Neurosciences, Inc. | Methods of screening for β-amyloid peptide production inhibitors |
EP0799305A4 (de) * | 1994-12-05 | 2000-01-26 | Merck & Co Inc | Transgenes tier mit mangel an amyloiden vorläuferprotein |
-
1999
- 1999-05-13 CA CA002328591A patent/CA2328591A1/en not_active Abandoned
- 1999-05-13 AU AU39006/99A patent/AU769734B2/en not_active Ceased
- 1999-05-13 WO PCT/US1999/010431 patent/WO1999060100A1/en active IP Right Grant
- 1999-05-13 ES ES99921917T patent/ES2262321T3/es not_active Expired - Lifetime
- 1999-05-13 EP EP99921917A patent/EP1082408B1/de not_active Expired - Lifetime
- 1999-05-13 DE DE69930932T patent/DE69930932T2/de not_active Expired - Lifetime
- 1999-05-13 AT AT99921917T patent/ATE323757T1/de not_active IP Right Cessation
- 1999-05-13 US US09/311,509 patent/US6166289A/en not_active Expired - Lifetime
- 1999-05-13 DK DK99921917T patent/DK1082408T3/da active
Also Published As
Publication number | Publication date |
---|---|
DK1082408T3 (da) | 2006-08-21 |
DE69930932T2 (de) | 2006-11-23 |
US6166289A (en) | 2000-12-26 |
EP1082408A4 (de) | 2002-04-10 |
DE69930932D1 (de) | 2006-05-24 |
CA2328591A1 (en) | 1999-11-25 |
ES2262321T3 (es) | 2006-11-16 |
WO1999060100A1 (en) | 1999-11-25 |
AU769734B2 (en) | 2004-02-05 |
EP1082408A1 (de) | 2001-03-14 |
EP1082408B1 (de) | 2006-04-19 |
AU3900699A (en) | 1999-12-06 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |