NO981500D0 - Multi-functional hematopoietic receptor antagonists - Google Patents

Multi-functional hematopoietic receptor antagonists

Info

Publication number
NO981500D0
NO981500D0 NO981500A NO981500A NO981500D0 NO 981500 D0 NO981500 D0 NO 981500D0 NO 981500 A NO981500 A NO 981500A NO 981500 A NO981500 A NO 981500A NO 981500 D0 NO981500 D0 NO 981500D0
Authority
NO
Norway
Prior art keywords
receptor antagonists
hematopoietic receptor
functional hematopoietic
functional
antagonists
Prior art date
Application number
NO981500A
Other languages
Norwegian (no)
Other versions
NO981500L (en
Inventor
Yiqing Feng
Nicholas R Staten
Charles M Baum
Neena L Summers
Maire H Caparon
S C Bauer
Linda Zurfluh
John P Mckearn
Barbara Kure Klein
Stephen C Lee
Charles A Mcwherter
Judith G Giri
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO981500D0 publication Critical patent/NO981500D0/en
Publication of NO981500L publication Critical patent/NO981500L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO981500A 1995-10-05 1998-04-02 Multi-functional hematopoietic receptor antagonists NO981500L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US483495P 1995-10-05 1995-10-05
PCT/US1996/015774 WO1997012985A2 (en) 1995-10-05 1996-10-04 Multi-functional hematopoietic receptor agonists

Publications (2)

Publication Number Publication Date
NO981500D0 true NO981500D0 (en) 1998-04-02
NO981500L NO981500L (en) 1998-05-20

Family

ID=21712756

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981500A NO981500L (en) 1995-10-05 1998-04-02 Multi-functional hematopoietic receptor antagonists

Country Status (14)

Country Link
EP (1) EP0854928A2 (en)
JP (1) JPH11510062A (en)
KR (1) KR100456212B1 (en)
CN (2) CN1590407A (en)
AU (1) AU705083B2 (en)
BR (1) BRPI9610977A2 (en)
CA (1) CA2234061A1 (en)
CZ (1) CZ295518B6 (en)
IL (1) IL123832A0 (en)
MX (1) MX9802730A (en)
NO (1) NO981500L (en)
NZ (1) NZ320978A (en)
PL (1) PL184424B1 (en)
WO (1) WO1997012985A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US6967092B1 (en) 1996-10-25 2005-11-22 Mc Kearn John P Multi-functional chimeric hematopoietic receptor agonists
US5969105A (en) * 1996-10-25 1999-10-19 Feng; Yiqing Stem cell factor receptor agonists
US6660257B1 (en) * 1996-10-25 2003-12-09 Pharmacia Corporation Circular permuteins of flt3 ligand
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
US6242570B1 (en) 1997-07-10 2001-06-05 Beth Israel Deaconess Medical Center Production and use of recombinant protein multimers with increased biological activity
US6187564B1 (en) 1997-07-10 2001-02-13 Beth Israel Deaconess Medical Center DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
AU7825500A (en) * 1999-10-07 2001-04-23 Pharmacia Corporation Inhibition enzyme linked immunosorbent assay (iELISA) for the detection and quantification of antibodies in biological samples
CA2452582C (en) 2001-07-11 2013-01-22 Maxygen Holdings, Ltd. G-csf conjugates
AU2006254543A1 (en) 2005-06-01 2006-12-07 Maxygen Holdings Ltd. PEGylated G-CSF polypeptides and methods of producing same
WO2007075899A2 (en) * 2005-12-21 2007-07-05 Maxygen, Inc. Dual agonist compounds and uses thereof
CN102675472B (en) * 2012-05-07 2014-07-30 北京诺派生物科技有限公司 Kit for detecting pig suffering from porcine reproductive and respiratory syndrome
EP2934555B1 (en) * 2012-12-21 2021-09-22 Astellas Institute for Regenerative Medicine Methods for production of platelets from pluripotent stem cells
LT6161B (en) 2013-09-27 2015-06-25 Uab Profarma Fused proteins of granulocyte colony-stimulating factor with other partners of growh factor, preferably with stem cell factor, and method of preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6057133A (en) * 1992-11-24 2000-05-02 G. D. Searle Multivariant human IL-3 fusion proteins and their recombinant production
US5635599A (en) * 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands

Also Published As

Publication number Publication date
AU7384496A (en) 1997-04-28
PL184424B1 (en) 2002-10-31
NZ320978A (en) 2001-03-30
AU705083B2 (en) 1999-05-13
NO981500L (en) 1998-05-20
CN1590407A (en) 2005-03-09
WO1997012985A2 (en) 1997-04-10
CA2234061A1 (en) 1997-04-10
MX9802730A (en) 1998-09-30
IL123832A0 (en) 1998-10-30
PL326072A1 (en) 1998-08-17
JPH11510062A (en) 1999-09-07
CN1204369A (en) 1999-01-06
KR100456212B1 (en) 2005-01-15
CZ96598A3 (en) 1998-09-16
WO1997012985A3 (en) 1997-08-07
CZ295518B6 (en) 2005-08-17
EP0854928A2 (en) 1998-07-29
BRPI9610977A2 (en) 2019-09-17
KR19990064068A (en) 1999-07-26
CN1124348C (en) 2003-10-15

Similar Documents

Publication Publication Date Title
NO972016D0 (en) Indolyl-Y receptor antagonists
BR9612381A (en) Vitronectin receptor antagonists
NO983003D0 (en) Vitronectin receptor antagonists
NO983002D0 (en) Vitronectin receptor antagonists
BR9508178A (en) Vitronectin receptor antagonists
FI960953A (en) endothelin receptor antagonists
DE69812096D1 (en) NEUROPEPTID Y RECEPTOR ANTAGONISTS
PT1009732E (en) 1-AMINO-ALKYLCICLO-HEXANES ANTAGONISTS OF THE NMDA RECEPTOR
DE69734833D1 (en) VITRONEKTIN RECEPTOR ANTAGONISTS
FI961804A (en) endothelin receptor antagonists
NO960081L (en) Estrogen agonist / antagonists
DE69327720D1 (en) ENDOTHELIN RECEPTOR ANTAGONISTS
ATE213156T1 (en) ENDOTHELIN RECEPTOR ANTAGONISTS
DK0741133T3 (en) Adhesion receptor antagonists
ID24726A (en) TROMBIN RECEPTOR ANTAGONISTS
NO981500L (en) Multi-functional hematopoietic receptor antagonists
ID24162A (en) VITRONECTTIN RECEPTOR ANTAGONISTS
BR9707733A (en) Oxa-e-thia-diazole muscarinic receptor antagonists
DK0906294T3 (en) Benzoxazinone-dopamine D4 receptor antagonists
BR9507220A (en) Endothelin receptor antagonists
NO991948D0 (en) Multi-functional, chimeric hematopoietic receptor antagonists
ATE341324T1 (en) ENDOTHELIN RECEPTOR ANTAGONISTS
DE69616364D1 (en) ENDOTHELINE RECEPTOR ANTAGONISTS
BR9603432A (en) Endothelin receptor antagonists

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application