NO980648L - Fremgangsmåte for diagnostisk bildeanalyse ved anvendelse av metallkomplekser av nitrogeninneholdende makrocykliske ligander - Google Patents

Fremgangsmåte for diagnostisk bildeanalyse ved anvendelse av metallkomplekser av nitrogeninneholdende makrocykliske ligander

Info

Publication number
NO980648L
NO980648L NO980648A NO980648A NO980648L NO 980648 L NO980648 L NO 980648L NO 980648 A NO980648 A NO 980648A NO 980648 A NO980648 A NO 980648A NO 980648 L NO980648 L NO 980648L
Authority
NO
Norway
Prior art keywords
nitrogen
image analysis
metal complexes
diagnostic image
macrocyclic ligands
Prior art date
Application number
NO980648A
Other languages
English (en)
Norwegian (no)
Other versions
NO980648D0 (no
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of NO980648D0 publication Critical patent/NO980648D0/no
Publication of NO980648L publication Critical patent/NO980648L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO980648A 1995-08-17 1998-02-16 Fremgangsmåte for diagnostisk bildeanalyse ved anvendelse av metallkomplekser av nitrogeninneholdende makrocykliske ligander NO980648L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US242295P 1995-08-17 1995-08-17
PCT/US1996/013045 WO1997006831A1 (en) 1995-08-17 1996-08-16 Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands

Publications (2)

Publication Number Publication Date
NO980648D0 NO980648D0 (no) 1998-02-16
NO980648L true NO980648L (no) 1998-03-31

Family

ID=21700681

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980648A NO980648L (no) 1995-08-17 1998-02-16 Fremgangsmåte for diagnostisk bildeanalyse ved anvendelse av metallkomplekser av nitrogeninneholdende makrocykliske ligander

Country Status (9)

Country Link
US (1) US5976498A (xx)
EP (1) EP0844889A1 (xx)
JP (1) JPH11514971A (xx)
AU (1) AU6722496A (xx)
BR (1) BR9610240A (xx)
CA (1) CA2229777A1 (xx)
NO (1) NO980648L (xx)
NZ (1) NZ315505A (xx)
WO (1) WO1997006831A1 (xx)

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Publication number Priority date Publication date Assignee Title
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
AU6896796A (en) * 1995-08-17 1997-03-12 Monsanto Company Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
US20050171198A1 (en) * 1997-06-20 2005-08-04 Metaphore Pharmaceuticals, Inc. SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease
DE69813898T2 (de) 1997-11-03 2004-03-11 Duke University Substituierte porphyrinen
DE60024588T2 (de) 1999-01-25 2006-08-17 National Jewish Medical And Research Center, Denver Substituierte porphyrine und deren therapeutische verwendungen
US20030069281A1 (en) * 2000-06-14 2003-04-10 Irwin Fridovich Tetrapyrroles
JP2004520380A (ja) 2001-01-19 2004-07-08 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 癌治療本出願は、２００１年１月１９日に出願の仮出願番号第６０／２６２，３９０号の優先権を主張し、その全ての内容は、参照により本願明細書に援用したものとする。
WO2002098431A1 (en) 2001-06-01 2002-12-12 National Jewish Medical And Research Center Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
WO2003103680A1 (en) * 2002-06-07 2003-12-18 Duke University Substituted porphyrins
WO2006037050A2 (en) * 2004-09-24 2006-04-06 Metaphore Pharmaceuticals, Inc. Methods for treating congestive heart failure
US8217166B2 (en) * 2005-05-05 2012-07-10 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
US20120301403A1 (en) 2007-06-21 2012-11-29 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
US9855279B2 (en) 2006-10-12 2018-01-02 Galera Labs, Llc Methods of treating oral mucositis
US9198893B2 (en) 2008-05-22 2015-12-01 Galera Labs, Llc Combination antitumor therapy
MX2010012593A (es) 2008-05-23 2011-03-04 Nat Jewish Health Metodos para el tratamiento de lesion asociada con exposicion a especie alcalina.
US9149483B2 (en) 2011-09-26 2015-10-06 Galera Labs, Llc Methods for treatment of diseases
CN108350009B (zh) 2015-08-11 2021-07-09 加莱拉实验室有限责任公司 具有口服生物利用率的五氮杂大环状环络合物
EA201992431A1 (ru) 2017-10-13 2020-03-13 ГАЛЕРА ЛЭБЗ, ЭлЭлСи Комбинированная иммунотерапия рака с использованием пента-аза-макроциклического кольцевого комплекса
BR112020015520A2 (pt) 2018-01-31 2021-02-02 Galera Labs, Llc terapia de combinação para câncer com complexo de anel macrocíclico pentaaza e agente anticâncer à base de platina

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US4001212A (en) * 1973-10-03 1977-01-04 E. I. Du Pont De Nemours And Company Macrocyclic polyamines
NO149961C (no) * 1981-06-01 1984-07-25 Borregaard Ind Fremgangsmaate for fremstilling av n-(2-hydroksyetyl)-derivater av makrocykliske polyaminer, inneholdende flere nitrogenatomer i 1,4-forhold i ringen
US5316757A (en) * 1984-10-18 1994-05-31 Board Of Regents, The University Of Texas System Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups
FR2614020B1 (fr) * 1987-04-14 1989-07-28 Guerbet Sa Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands.
US5049667A (en) * 1987-04-14 1991-09-17 Guerbet S.A. Nitrogen-containing cyclic ligands
US5064956A (en) * 1987-06-24 1991-11-12 The Dow Chemical Company Process for preparing mono-n-alkylated polyazamacrocycles
CA1340527C (en) * 1988-05-31 1999-05-04 Lidia Vallarino Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
US5252720A (en) * 1989-03-06 1993-10-12 Board Of Regents, The University Of Texas System Metal complexes of water soluble texaphyrins
US5292868A (en) * 1989-05-26 1994-03-08 Akzo N.V. Chelating agents for attaching metal ions to proteins
GB9001245D0 (en) * 1990-01-19 1990-03-21 Salutar Inc Compounds
WO1991010669A1 (en) * 1990-01-19 1991-07-25 Cockbain, Julian, Roderick, Michaelson Chelating compounds
US5162109A (en) * 1990-09-13 1992-11-10 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
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CA2102605A1 (en) * 1991-05-23 1992-11-24 Evan C. Unger Liposoluble compounds for magnetic resonance imaging
CA2072934C (en) * 1991-07-19 2007-08-28 Karl William Aston Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
WO1993002090A1 (en) * 1991-07-19 1993-02-04 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
AU4237493A (en) * 1993-05-06 1994-12-12 Dow Chemical Company, The Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals
HUT76318A (en) * 1994-04-22 1997-08-28 Searle & Co Diagnostic image analysis with metal complexes
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
WO1996040658A1 (en) * 1995-06-07 1996-12-19 Monsanto Company Process for preparing substituted polyazamacrocycles

Also Published As

Publication number Publication date
NZ315505A (en) 2000-01-28
US5976498A (en) 1999-11-02
AU6722496A (en) 1997-03-12
NO980648D0 (no) 1998-02-16
WO1997006831A1 (en) 1997-02-27
EP0844889A1 (en) 1998-06-03
CA2229777A1 (en) 1997-02-27
JPH11514971A (ja) 1999-12-21
BR9610240A (pt) 1999-06-29

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