NO972475L - Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav - Google Patents

Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav

Info

Publication number
NO972475L
NO972475L NO972475A NO972475A NO972475L NO 972475 L NO972475 L NO 972475L NO 972475 A NO972475 A NO 972475A NO 972475 A NO972475 A NO 972475A NO 972475 L NO972475 L NO 972475L
Authority
NO
Norway
Prior art keywords
preparation
formulation
new antithrombotic
antithrombotic formulation
new
Prior art date
Application number
NO972475A
Other languages
English (en)
Other versions
NO972475D0 (no
Inventor
Jan-Erik Loefroth
Anna-Lena Ungell
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO972475D0 publication Critical patent/NO972475D0/no
Publication of NO972475L publication Critical patent/NO972475L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Ny farmasfaytisk formulering omfattende trombininhibitoren H00C-CH2-(R)-Cgl-Aze- Pab i kombinasjon med ett eller flere absorpsjonsforsterkende midler, en fremgangsmåte for fremstilling av en slik farmasøytisk formulering, anvendelse av en slik formulering i behandlingen av tromboembolisme samt en metode for behandling av en pasient som har behov for antitrombotisk behandling og tromboembolisme ved bruk av nevnte formulering.
NO972475A 1994-12-02 1997-05-30 Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav NO972475L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404196A SE9404196D0 (sv) 1994-12-02 1994-12-02 New antithrombotic formulation
PCT/SE1995/001425 WO1996016671A1 (en) 1994-12-02 1995-11-29 New antithrombotic formulation, process for its manufacturing, and use thereof

Publications (2)

Publication Number Publication Date
NO972475D0 NO972475D0 (no) 1997-05-30
NO972475L true NO972475L (no) 1997-05-30

Family

ID=20396207

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972475A NO972475L (no) 1994-12-02 1997-05-30 Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav

Country Status (27)

Country Link
US (1) US5795896A (no)
EP (1) EP0799052B1 (no)
JP (1) JPH10513438A (no)
CN (1) CN1168635A (no)
AR (1) AR002254A1 (no)
AT (1) ATE208628T1 (no)
AU (1) AU689994B2 (no)
BR (1) BR9509853A (no)
CA (1) CA2206459A1 (no)
CZ (1) CZ147097A3 (no)
DE (1) DE69523943T2 (no)
DK (1) DK0799052T3 (no)
EE (1) EE03338B1 (no)
ES (1) ES2168395T3 (no)
FI (1) FI972332A0 (no)
HU (1) HU216631B (no)
IL (1) IL116153A (no)
IS (1) IS4483A (no)
NO (1) NO972475L (no)
NZ (1) NZ297118A (no)
PL (1) PL320692A1 (no)
PT (1) PT799052E (no)
SE (1) SE9404196D0 (no)
SK (1) SK61797A3 (no)
TR (1) TR199501517A2 (no)
WO (1) WO1996016671A1 (no)
ZA (1) ZA9510242B (no)

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SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
US6984627B1 (en) * 1993-06-03 2006-01-10 Astrazeneca Ab Peptide derivatives
AR005245A1 (es) 1995-12-21 1999-04-28 Astrazeneca Ab Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion
GB9526273D0 (en) * 1995-12-21 1996-02-21 Astra Ab New prodrugs
SE9602145D0 (sv) * 1996-05-31 1996-05-31 Astra Ab New improved formulation for treatment of thromboembolism
US6423334B1 (en) * 1997-10-01 2002-07-23 Elan Corporation, Plc Composition and method for enhancing transport across gastrointestinal tract cell layers
AR023510A1 (es) * 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
AR023819A1 (es) * 1999-05-03 2002-09-04 Astrazeneca Ab FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION
SE9902550D0 (sv) * 1999-07-02 1999-07-02 Astra Ab New crystalline forms
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
KR100994221B1 (ko) 2001-06-14 2010-11-12 오츠카 세이야쿠 가부시키가이샤 의약 조성물
SE0103590D0 (sv) * 2001-10-26 2001-10-26 Astrazeneca Ab New Combination
SE0203349D0 (sv) * 2002-11-12 2002-11-12 Astrazeneca Ab New use
US7479502B2 (en) 2002-12-03 2009-01-20 Pharmacyclics, Inc. 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US20060046962A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US20090047347A1 (en) * 2005-07-29 2009-02-19 Aegis Therapeutics, Inc. Compositions for Drug Administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
RU2354647C2 (ru) 2007-06-28 2009-05-10 Общество С Ограниченной Ответственностью "Бионика" Новые соединения, обладающие функцией ингибиторов тромбина, и фармацевтические композиции на их основе
WO2009121039A2 (en) 2008-03-28 2009-10-01 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US8895546B2 (en) 2009-03-27 2014-11-25 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US8541360B2 (en) * 2008-11-19 2013-09-24 Ben Venue Laboratories, Inc. Parenteral formulations comprising sugar-based esters and ethers
US8440631B2 (en) * 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
US20100215730A1 (en) * 2009-02-20 2010-08-26 Intrepid Therapeutics, Inc. Compositions for Nasal Administration of Phenothiazines
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
US20110070293A1 (en) 2009-09-23 2011-03-24 Javeri Indu Methods for the Preparation of Liposomes Comprising Docetaxel
EA202091615A1 (ru) 2018-12-21 2021-03-05 Аегис Терапьютикс, Ллс Интраназальные составы на основе эпинефрина и способы лечения заболевания

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HU178398B (en) * 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4568636A (en) * 1981-03-25 1986-02-04 Pentapharm Ag Tripeptide derivatives
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IL99527A (en) * 1990-09-28 1997-08-14 Lilly Co Eli Tripeptide antithrombotic agents
GB9024129D0 (en) * 1990-11-06 1990-12-19 Thrombosis Research Trust Inhibitors and substrates of thrombin
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DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
SE9102462D0 (sv) * 1991-08-28 1991-08-28 Astra Ab New isosteric peptides
ZA928581B (en) * 1991-11-12 1994-05-06 Lilly Co Eli Antithrombotic agents
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives

Also Published As

Publication number Publication date
HUT77655A (hu) 1998-07-28
CN1168635A (zh) 1997-12-24
NO972475D0 (no) 1997-05-30
DE69523943D1 (de) 2001-12-20
WO1996016671A1 (en) 1996-06-06
SE9404196D0 (sv) 1994-12-02
AU689994B2 (en) 1998-04-09
BR9509853A (pt) 1997-12-30
NZ297118A (en) 1998-12-23
FI972332A (fi) 1997-06-02
ES2168395T3 (es) 2002-06-16
CA2206459A1 (en) 1996-06-06
ATE208628T1 (de) 2001-11-15
PL320692A1 (en) 1997-10-27
DK0799052T3 (da) 2002-02-25
EP0799052B1 (en) 2001-11-14
SK61797A3 (en) 1998-03-04
AR002254A1 (es) 1998-03-11
US5795896A (en) 1998-08-18
HU216631B (hu) 1999-07-28
DE69523943T2 (de) 2002-06-27
IL116153A0 (en) 1996-01-31
AU4191596A (en) 1996-06-19
PT799052E (pt) 2002-05-31
CZ147097A3 (cs) 1998-02-18
IS4483A (is) 1997-05-16
FI972332A0 (fi) 1997-06-02
ZA9510242B (en) 1996-06-03
EP0799052A1 (en) 1997-10-08
MX9703975A (es) 1997-09-30
EE03338B1 (et) 2001-02-15
IL116153A (en) 1999-11-30
JPH10513438A (ja) 1998-12-22
TR199501517A2 (tr) 1996-07-21

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Legal Events

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