NO972339L - Methods for detecting spongiform encephalopathy - Google Patents

Methods for detecting spongiform encephalopathy

Info

Publication number
NO972339L
NO972339L NO972339A NO972339A NO972339L NO 972339 L NO972339 L NO 972339L NO 972339 A NO972339 A NO 972339A NO 972339 A NO972339 A NO 972339A NO 972339 L NO972339 L NO 972339L
Authority
NO
Norway
Prior art keywords
spongiform encephalopathy
detecting
animal
methods
agent
Prior art date
Application number
NO972339A
Other languages
Norwegian (no)
Other versions
NO972339D0 (en
Inventor
Michael Dawson
Trevor Conrad Martin
Paula Keyes
Verity Jones
Original Assignee
Mini Agriculture & Fisheries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9424015A external-priority patent/GB9424015D0/en
Application filed by Mini Agriculture & Fisheries filed Critical Mini Agriculture & Fisheries
Publication of NO972339L publication Critical patent/NO972339L/en
Publication of NO972339D0 publication Critical patent/NO972339D0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Fremgangsmåte for å påvise tilstedeværelsen av spongiform encefalopati i et dyr omfattende bestemmelse av tilstede- værelsen og/eller mengden av et middel (f.eks. ved anvendelse av 2DPAGE etterfulgt av farging og densitometriavlesninger av det fargede middel) i et kroppsfluid (f.eks. cerebrospinal- fluid) fra et testdyr, som kryssreagerer med antistoff dannet mot apolipoprotein E, og som har en molekylvekt mellom 34 og 38 kDa og en pl mellom 5,4 og 5,7, sammenligne konsentra- sjonen med en kontrollverdi og korrelere sammenhengen mellom de to med den sannsynligvise tilstedeværelse av spongiform encefalopati i dyret.A method for detecting the presence of spongiform encephalopathy in an animal comprising determining the presence and / or amount of agent (e.g., using 2DPAGE followed by staining and densitometry readings of the colored agent) in a body fluid (e.g. (cerebrospinal fluid) from a test animal, which cross-reacts with antibody produced against apolipoprotein E and has a molecular weight between 34 and 38 kDa and a pI between 5.4 and 5.7, compare the concentration to a control value and correlate the relationship between the two with the likely presence of spongiform encephalopathy in the animal.

NO972339A 1994-11-29 1997-05-22 Methods for detecting spongiform encephalopathy NO972339D0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9424015A GB9424015D0 (en) 1994-11-29 1994-11-29 Spongiform encepmalopathy detection methods
GBGB9424769.9A GB9424769D0 (en) 1994-11-29 1994-12-07 Spongiform encephalopathy detection methods
PCT/GB1995/002766 WO1996017249A1 (en) 1994-11-29 1995-11-28 Spongiform encephalopathy detection methods

Publications (2)

Publication Number Publication Date
NO972339L true NO972339L (en) 1997-05-22
NO972339D0 NO972339D0 (en) 1997-05-22

Family

ID=26306057

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972339A NO972339D0 (en) 1994-11-29 1997-05-22 Methods for detecting spongiform encephalopathy

Country Status (11)

Country Link
EP (1) EP0795132A1 (en)
AU (1) AU3932895A (en)
CA (1) CA2205179A1 (en)
CZ (1) CZ164297A3 (en)
FI (1) FI972253A (en)
GB (1) GB2308659B (en)
HU (1) HUT77340A (en)
NO (1) NO972339D0 (en)
NZ (1) NZ295721A (en)
SK (1) SK67897A3 (en)
WO (1) WO1996017249A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2268904A1 (en) 1996-10-15 1998-04-23 Imperial College Of Science, Technology And Medicine Diagnosis of spongiform encephalopathy
GB2354946B (en) * 1996-10-15 2001-05-16 Imperial College Means for the treatment of prion disease
GB9701045D0 (en) * 1997-01-18 1997-03-05 Narang Harash K Diagnosis of neuro-degenerative disorders
JP2001520755A (en) * 1998-02-06 2001-10-30 ナラン，ハラシュ，クマール Diagnosis of neurodegenerative diseases
FR2827047B1 (en) * 2001-07-03 2003-09-26 Apoh Technollgies Sa PROCESS FOR SEPARATION AND / OR DETECTION AND / OR IDENTIFICATION AND / OR QUANTIFICATION OF PRION PROTEINS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892814A (en) * 1987-06-22 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Method for distinguishing Creutzfeldt-Jakob disease from other dementias

Also Published As

Publication number Publication date
FI972253A (en) 1997-07-28
SK67897A3 (en) 2000-02-14
GB2308659A (en) 1997-07-02
CA2205179A1 (en) 1996-06-06
AU3932895A (en) 1996-06-19
HUT77340A (en) 1998-03-30
GB2308659B (en) 1998-11-18
GB9708663D0 (en) 1997-06-18
EP0795132A1 (en) 1997-09-17
NZ295721A (en) 1999-03-29
WO1996017249A1 (en) 1996-06-06
FI972253A0 (en) 1997-05-28
NO972339D0 (en) 1997-05-22
CZ164297A3 (en) 1997-11-12

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