NO971668L - Lyofilisat av lipid-kompleks av vannuopplöselige camptotekiner - Google Patents

Lyofilisat av lipid-kompleks av vannuopplöselige camptotekiner

Info

Publication number
NO971668L
NO971668L NO971668A NO971668A NO971668L NO 971668 L NO971668 L NO 971668L NO 971668 A NO971668 A NO 971668A NO 971668 A NO971668 A NO 971668A NO 971668 L NO971668 L NO 971668L
Authority
NO
Norway
Prior art keywords
lyophilisate
water
lipid complex
camptothecins
insoluble
Prior art date
Application number
NO971668A
Other languages
English (en)
Other versions
NO971668D0 (no
NO323582B1 (no
Inventor
Mathew Cherian
Original Assignee
Pharmacia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Inc filed Critical Pharmacia Inc
Publication of NO971668D0 publication Critical patent/NO971668D0/no
Publication of NO971668L publication Critical patent/NO971668L/no
Publication of NO323582B1 publication Critical patent/NO323582B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19971668A 1994-10-14 1997-04-11 Lyofilisat av lipid-kompleks av vannuopploselige camptotekiner NO323582B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32308194A 1994-10-14 1994-10-14
PCT/US1995/014105 WO1996011669A1 (en) 1994-10-14 1995-10-11 Lyophilizate of lipid complex of water insoluble camptothecins

Publications (3)

Publication Number Publication Date
NO971668D0 NO971668D0 (no) 1997-04-11
NO971668L true NO971668L (no) 1997-04-11
NO323582B1 NO323582B1 (no) 2007-06-11

Family

ID=23257667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19971668A NO323582B1 (no) 1994-10-14 1997-04-11 Lyofilisat av lipid-kompleks av vannuopploselige camptotekiner

Country Status (18)

Country Link
US (1) US6548071B1 (no)
EP (1) EP0785772A4 (no)
JP (2) JPH10507454A (no)
KR (1) KR100387744B1 (no)
CN (1) CN1138543C (no)
AU (1) AU689983B2 (no)
CA (1) CA2202531C (no)
HU (1) HUT77975A (no)
IL (1) IL115099A (no)
MY (1) MY113203A (no)
NO (1) NO323582B1 (no)
NZ (1) NZ296389A (no)
PL (1) PL183040B1 (no)
RU (1) RU2169555C2 (no)
TW (1) TW450811B (no)
UA (1) UA64692C2 (no)
WO (1) WO1996011669A1 (no)
ZA (1) ZA957860B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19758157A1 (de) * 1997-03-27 1998-10-01 Sueddeutsche Kalkstickstoff Homogene, Glycerophospholipide und polare oder lipophile Substanzen enthaltende, wasserfreie Formulierungen und Verfahren zu deren Herstellung
GB9925127D0 (en) * 1999-10-22 1999-12-22 Pharmacia & Upjohn Spa Oral formulations for anti-tumor compounds
US20040009229A1 (en) * 2000-01-05 2004-01-15 Unger Evan Charles Stabilized nanoparticle formulations of camptotheca derivatives
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
US7838034B2 (en) 2002-07-30 2010-11-23 Grunenthal Gmbh Intravenous pharmaceutical form of administration
DE10234784A1 (de) * 2002-07-30 2004-02-19 Günenthal GmbH Intravenös applizierbare, pharmazeutische Darreichungsform
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
WO2004035032A2 (en) * 2002-08-20 2004-04-29 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
US20040247624A1 (en) * 2003-06-05 2004-12-09 Unger Evan Charles Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility
WO2005002546A1 (en) * 2003-06-27 2005-01-13 Smithkline Beecham Corporation Stabilized topotecan liposomal composition and methods
JP4433918B2 (ja) * 2004-07-15 2010-03-17 コニカミノルタエムジー株式会社 画像形成方法
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
CN1326525C (zh) * 2004-11-26 2007-07-18 复旦大学 10－羟基喜树碱长循环脂质体及其冻干制剂
TW200727900A (en) * 2005-07-27 2007-08-01 Yakult Honsha Kk Aqueous solution preparation containing camptothecins
WO2007067784A2 (en) * 2005-12-08 2007-06-14 Wyeth Liposomal compositions
CN101028251B (zh) * 2007-02-14 2010-05-19 四川大学 喜树碱衍生物磷脂复合物脂质纳米粒制剂及其制备方法
CN101721364B (zh) * 2009-11-10 2014-05-21 沈阳药科大学 一种喜树碱类化合物磷脂复合物水分散体及其制备方法
CN104837483B (zh) 2012-11-20 2017-09-01 光谱医药公司 制备治疗用途的脂质体封装式长春新碱的改进方法
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
DE102018200520A1 (de) * 2018-01-15 2019-07-18 Robert Bosch Gmbh Verfahren zum Bereitstellen einer Lösung der Substanz in einer mikrofluidischen Vorrichtung

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT347054B (de) * 1973-09-29 1978-12-11 Takeda Chemical Industries Ltd Verfahren zur herstellung von neuen nonapeptidamid-derivaten
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CH621479A5 (no) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4610868A (en) 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
US5279811A (en) * 1987-02-18 1994-01-18 The Du Pont Merck Pharmaceutical Company Ester-substituted diaminedithiols and radiolabeled complexes thereof
US5616334A (en) * 1987-03-05 1997-04-01 The Liposome Company, Inc. Low toxicity drug-lipid systems
MX9203504A (es) * 1988-04-20 1992-07-01 Liposome Co Inc Complejo agente: lipido activo de alta proporcion.
US5077057A (en) 1989-04-05 1991-12-31 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5389377A (en) 1989-12-22 1995-02-14 Molecular Bioquest, Inc. Solid care therapeutic compositions and methods for making same
US5552156A (en) * 1992-10-23 1996-09-03 Ohio State University Liposomal and micellular stabilization of camptothecin drugs
AU6832794A (en) * 1993-05-19 1994-12-12 Liposome Company, Inc., The Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
JPH09504517A (ja) * 1993-09-27 1997-05-06 スミスクライン・ビーチャム・コーポレイション カンプトテシン処方物
US5834012A (en) * 1995-05-03 1998-11-10 Roman Perez-Soler Lipid complexed topoisomerase I inhibitors
US6090407A (en) * 1997-09-23 2000-07-18 Research Development Foundation Small particle liposome aerosols for delivery of anti-cancer drugs

Also Published As

Publication number Publication date
EP0785772A4 (en) 2005-12-21
NO971668D0 (no) 1997-04-11
KR970706792A (ko) 1997-12-01
AU4018595A (en) 1996-05-06
JP2008024717A (ja) 2008-02-07
IL115099A0 (en) 1995-12-08
PL183040B1 (pl) 2002-05-31
JPH10507454A (ja) 1998-07-21
RU2169555C2 (ru) 2001-06-27
CN1138543C (zh) 2004-02-18
HUT77975A (hu) 1999-01-28
UA64692C2 (en) 2004-03-15
NO323582B1 (no) 2007-06-11
NZ296389A (en) 1999-06-29
EP0785772A1 (en) 1997-07-30
CN1160344A (zh) 1997-09-24
ZA957860B (en) 1996-05-21
KR100387744B1 (ko) 2003-11-28
AU689983B2 (en) 1998-04-09
CA2202531A1 (en) 1996-04-25
WO1996011669A1 (en) 1996-04-25
US6548071B1 (en) 2003-04-15
IL115099A (en) 1999-04-11
TW450811B (en) 2001-08-21
MY113203A (en) 2001-12-31
CA2202531C (en) 2005-05-03
PL319588A1 (en) 1997-08-18

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