NO970895L - Fenylpeptider, fremgangsmåte for fremstilling av disse, og farmasöytiske preparater inneholdende disse peptider - Google Patents

Fenylpeptider, fremgangsmåte for fremstilling av disse, og farmasöytiske preparater inneholdende disse peptider

Info

Publication number
NO970895L
NO970895L NO970895A NO970895A NO970895L NO 970895 L NO970895 L NO 970895L NO 970895 A NO970895 A NO 970895A NO 970895 A NO970895 A NO 970895A NO 970895 L NO970895 L NO 970895L
Authority
NO
Norway
Prior art keywords
peptides
phenyl
amino
formula
preparation
Prior art date
Application number
NO970895A
Other languages
English (en)
Other versions
NO970895D0 (no
Inventor
Valerie Niddam
Michel Camplo
Jean-Louis Kraus
Original Assignee
Lab Laphal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Laphal filed Critical Lab Laphal
Publication of NO970895D0 publication Critical patent/NO970895D0/no
Publication of NO970895L publication Critical patent/NO970895L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Syntetisk peptid for anvendelse i organisk kjemi og særlig i terapeutisk kjemi. Peptidet inneholder minst ni aminosyrer med formel (I), hvori X og Y er beskyttede eller ubeskyttede amino- syrerester eller peptider, R er et rett eller forgrenet alkylradikal. R'' er et alkylradikal, fenyl, halogen, nitro, amino, alkylamino, alkoksy, trifluoro- metyl, trifluorometoksy, karboksamido eller cyano, Z er svovel, oksygen, amino eller sulfoksid, og n er 0, 1, 2 eller 3. Forbindelsene med formel (I) er HIV-replikasjonsinhibitorer ved at de henuner en liten aspartyl- proteasedimer som spesifikt kutter for- løpere til et polyprotein som koder for HlV-enzymer og strukturelle proteiner.
NO970895A 1995-06-29 1997-02-27 Fenylpeptider, fremgangsmåte for fremstilling av disse, og farmasöytiske preparater inneholdende disse peptider NO970895L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9507817A FR2736055B1 (fr) 1995-06-29 1995-06-29 Nouveaux thiophenoxy peptides, leur procede de preparation et les compositions pharmaceutiques en renfermant
PCT/FR1996/001008 WO1997001576A2 (fr) 1995-06-29 1996-06-28 Peptides phenyles, leur procede de preparation et les compositions pharmaceutiques qui en renferment

Publications (2)

Publication Number Publication Date
NO970895D0 NO970895D0 (no) 1997-02-27
NO970895L true NO970895L (no) 1997-02-27

Family

ID=9480502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970895A NO970895L (no) 1995-06-29 1997-02-27 Fenylpeptider, fremgangsmåte for fremstilling av disse, og farmasöytiske preparater inneholdende disse peptider

Country Status (17)

Country Link
US (1) US5844078A (no)
EP (1) EP0787143A2 (no)
JP (1) JPH10505613A (no)
KR (1) KR970705576A (no)
CN (1) CN1165521A (no)
AP (1) AP683A (no)
AU (1) AU706799B2 (no)
BR (1) BR9606455A (no)
CA (1) CA2197861A1 (no)
FR (1) FR2736055B1 (no)
HU (1) HUP9701940A3 (no)
IL (1) IL120341A (no)
NO (1) NO970895L (no)
NZ (1) NZ312726A (no)
OA (1) OA10403A (no)
PL (1) PL318880A1 (no)
WO (1) WO1997001576A2 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1292438B1 (it) * 1997-06-30 1999-02-08 Zambon Spa Derivati peptidomimetici inibitori suicidi della proliferazione del hiv
US6118226A (en) 1998-07-31 2000-09-12 Federal-Mogul World Wide, Inc. Electrodeless neon light module for vehicle lighting systems
US8886480B2 (en) 2011-06-27 2014-11-11 Synaptics Incorporated System and method for signaling in gradient sensor devices
US9188675B2 (en) 2012-03-23 2015-11-17 Synaptics Incorporated System and method for sensing multiple input objects with gradient sensor devices

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1193598A (en) * 1982-05-06 1985-09-17 Rafael Foguet 2-amino-benzoic acid derivatives and processes for their production
US4454065A (en) * 1982-05-18 1984-06-12 Smithkline Beckman Corporation Oligopeptide prodrugs
ZA832844B (en) * 1982-05-18 1984-03-28 Smithkline Beckman Corp Oligopeptide prodrugs
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
US5221667A (en) * 1990-01-22 1993-06-22 Warner-Lambert Company Renin inhibiting peptides having an α-heteroatom amino acid at the P3 position

Also Published As

Publication number Publication date
AU6462496A (en) 1997-01-30
BR9606455A (pt) 1998-07-14
CA2197861A1 (fr) 1997-01-16
EP0787143A2 (fr) 1997-08-06
NZ312726A (en) 1998-07-28
HUP9701940A3 (en) 2001-07-30
IL120341A0 (en) 1997-06-10
NO970895D0 (no) 1997-02-27
IL120341A (en) 2001-01-28
AP9700964A0 (en) 1997-04-30
JPH10505613A (ja) 1998-06-02
KR970705576A (ko) 1997-10-09
AP683A (en) 1998-09-30
WO1997001576A3 (fr) 1997-05-15
HUP9701940A2 (hu) 1998-03-02
WO1997001576A2 (fr) 1997-01-16
FR2736055A1 (fr) 1997-01-03
FR2736055B1 (fr) 1997-09-12
OA10403A (fr) 2001-12-05
US5844078A (en) 1998-12-01
AU706799B2 (en) 1999-06-24
CN1165521A (zh) 1997-11-19
PL318880A1 (en) 1997-07-07

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