NO964102L - Pharmaceuticals and drugs for the prevention and treatment of endothelial dysfunctions - Google Patents

Pharmaceuticals and drugs for the prevention and treatment of endothelial dysfunctions

Info

Publication number
NO964102L
NO964102L NO964102A NO964102A NO964102L NO 964102 L NO964102 L NO 964102L NO 964102 A NO964102 A NO 964102A NO 964102 A NO964102 A NO 964102A NO 964102 L NO964102 L NO 964102L
Authority
NO
Norway
Prior art keywords
prevention
treatment
pharmaceuticals
drugs
endothelial dysfunctions
Prior art date
Application number
NO964102A
Other languages
Norwegian (no)
Other versions
NO964102D0 (en
Inventor
Eike Albrecht Noack
Georg Kojda
Original Assignee
Isis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharma Gmbh filed Critical Isis Pharma Gmbh
Publication of NO964102D0 publication Critical patent/NO964102D0/en
Publication of NO964102L publication Critical patent/NO964102L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det er beskrevet anvendelse av nitrogenmonoksydfrlgivende eller ¿overførende forbindelser, av stlmulatorer av den endogene nitrogenmonoksyddannelsen samt av stimulatorer av guanylatzyklase for forebyggelse, behandling og helbredelse av endothellske dysfunksjoner og av med disse dysfunksjonene Innledede eller ved disse fremkalte sykdonroer, samt anvendelsen av nevnte forbindelser for fremstilling av farmasøytiske produkter for de nevnte anvendelsesområdene.There is disclosed the use of nitrogen monoxide releasing or transmitting compounds, of stimulators of the endogenous nitrogen monoxide formation and of guanylate cyclase stimulators for the prevention, treatment and cure of endothelial dysfunctions and of these dysfunctions. of pharmaceutical products for the aforementioned applications.

NO964102A 1994-03-30 1996-09-27 Pharmaceuticals and drugs for the prevention and treatment of endothelial dysfunctions NO964102L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4410997A DE4410997A1 (en) 1994-03-30 1994-03-30 Pharmaceutical preparations and drugs for the prevention and treatment of endothelial dysfunctions
PCT/DE1995/000421 WO1995026725A1 (en) 1994-03-30 1995-03-28 Pharmaceutical preparations and medicaments for the prevention and treatment of endothelial dysfunction

Publications (2)

Publication Number Publication Date
NO964102D0 NO964102D0 (en) 1996-09-27
NO964102L true NO964102L (en) 1996-09-27

Family

ID=6514213

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964102A NO964102L (en) 1994-03-30 1996-09-27 Pharmaceuticals and drugs for the prevention and treatment of endothelial dysfunctions

Country Status (19)

Country Link
EP (1) EP0752858A1 (en)
JP (1) JPH09510979A (en)
CN (1) CN1150387A (en)
BG (1) BG63073B1 (en)
CA (1) CA2186783A1 (en)
CZ (1) CZ283696A3 (en)
DE (2) DE4410997A1 (en)
EE (1) EE9600139A (en)
FI (1) FI963883A (en)
HU (1) HU220165B (en)
IS (1) IS4365A (en)
LT (1) LT4310B (en)
LV (1) LV11666B (en)
MX (1) MX9604434A (en)
NO (1) NO964102L (en)
PL (1) PL316528A1 (en)
SI (1) SI9520047A (en)
SK (1) SK121896A3 (en)
WO (1) WO1995026725A1 (en)

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GB9423868D0 (en) * 1994-11-25 1995-01-11 Wellcome Found Compounds for use in medicine
DE19654895C2 (en) * 1996-02-07 2000-07-27 Sanol Arznei Schwarz Gmbh Detection method
DE19604361C2 (en) * 1996-02-07 1999-01-14 Sanol Arznei Schwarz Gmbh Use of gas-tight primary packaging for pharmaceutical compositions
DE19726812A1 (en) * 1997-06-25 1999-01-07 Isis Pharma Gmbh New nitryl-oxy-methyl derivatives derived from pentaerythritol
US6331543B1 (en) 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
USRE37234E1 (en) 1996-11-01 2001-06-19 Nitromed, Inc. Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
DE19745622A1 (en) * 1997-10-16 1999-04-22 Isis Pharma Gmbh New nitric acid ester derivatives of pentaerythritol
ZA989356B (en) * 1997-10-16 1998-11-16 Isis Pharma Gmbh Pharmaceutical preparations
PL193215B1 (en) * 1997-10-17 2007-01-31 Eurogene Ltd Application of the renin-angiotensin system inhibitors
US6472425B1 (en) 1997-10-31 2002-10-29 Nitromed, Inc. Methods for treating female sexual dysfunctions
EP1087926A2 (en) * 1998-06-24 2001-04-04 Alpharma-Isis GmbH & Co. KG Analytic substrates and antioxidative agents
WO2001017528A1 (en) 1999-09-08 2001-03-15 Nitromed, Inc. Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
DE60042611D1 (en) 1999-10-29 2009-09-03 Nitromed Inc METHOD OF TREATING VASCULAR DISEASES, DIGITAL AWARDS
US7235237B2 (en) 1999-10-29 2007-06-26 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US7537785B2 (en) 1999-10-29 2009-05-26 Nitromed, Inc. Composition for treating vascular diseases characterized by nitric oxide insufficiency
US7708989B2 (en) 1999-10-29 2010-05-04 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
ES2258365B1 (en) * 2003-10-03 2007-12-01 Lacer, S.A. DERIVATIVES OF DISULFIDE, SULFIDE, SULFOXIDE AND SULFONE OF CYCLING SUGARS AND THEIR USES.
WO2008124505A2 (en) * 2007-04-05 2008-10-16 Ironwood Pharmaceuticals,Inc. Soluble guanylate cyclase (sgc) modulators for treatment of lipid related disorders
PE20130222A1 (en) * 2010-05-27 2013-03-14 Merck Sharp & Dohme SOLUBLE CYCLASE GUANILATE ACTIVATORS
RU2467748C1 (en) * 2011-08-08 2012-11-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" 3-(2,2,2-trimethylhydrazinium) propionate derivative - 3-(2,2,2-trimethylhydrazinium) potassium propionate glycinate exhibiting endothelioprotective activity
JP5360939B2 (en) * 2011-09-28 2013-12-04 国立大学法人徳島大学 A therapeutic agent for arteriosclerosis comprising a nitrosonifedipine derivative as an active ingredient

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Also Published As

Publication number Publication date
CN1150387A (en) 1997-05-21
JPH09510979A (en) 1997-11-04
PL316528A1 (en) 1997-01-20
BG63073B1 (en) 2001-03-30
DE19580261D2 (en) 1997-05-28
DE4410997A1 (en) 1995-10-26
LT4310B (en) 1998-03-25
CA2186783A1 (en) 1995-10-12
NO964102D0 (en) 1996-09-27
FI963883A0 (en) 1996-09-27
CZ283696A3 (en) 1998-03-18
EE9600139A (en) 1997-04-15
LV11666B (en) 1997-06-20
HU220165B (en) 2001-11-28
AU698359B2 (en) 1998-10-29
LV11666A (en) 1997-02-20
WO1995026725A1 (en) 1995-10-12
IS4365A (en) 1996-09-25
FI963883A (en) 1996-09-27
LT96148A (en) 1997-12-29
SI9520047A (en) 1997-06-30
AU2134595A (en) 1995-10-23
EP0752858A1 (en) 1997-01-15
HU9602671D0 (en) 1996-11-28
MX9604434A (en) 1997-12-31
SK121896A3 (en) 1998-10-07
BG100930A (en) 1997-07-31
HUT76676A (en) 1997-10-28

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