NO954722D0 - Peptid inhibitorer med urokinase reseptoraktivitet - Google Patents

Peptid inhibitorer med urokinase reseptoraktivitet

Info

Publication number
NO954722D0
NO954722D0 NO954722A NO954722A NO954722D0 NO 954722 D0 NO954722 D0 NO 954722D0 NO 954722 A NO954722 A NO 954722A NO 954722 A NO954722 A NO 954722A NO 954722 D0 NO954722 D0 NO 954722D0
Authority
NO
Norway
Prior art keywords
receptor activity
peptide inhibitors
urokinase receptor
urokinase
active
Prior art date
Application number
NO954722A
Other languages
English (en)
Other versions
NO954722L (no
Inventor
Steven Rosenberg
Michael V Doyle
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of NO954722L publication Critical patent/NO954722L/no
Publication of NO954722D0 publication Critical patent/NO954722D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
NO954722A 1993-05-28 1995-11-22 Peptid inhibitorer med urokinase reseptoraktivitet NO954722D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6151493A 1993-05-28 1993-05-28
PCT/US1994/005684 WO1994028014A2 (en) 1993-05-28 1994-05-19 Peptide inhibitors of urokinase receptor activity

Publications (2)

Publication Number Publication Date
NO954722L NO954722L (no) 1995-11-22
NO954722D0 true NO954722D0 (no) 1995-11-22

Family

ID=22036265

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954722A NO954722D0 (no) 1993-05-28 1995-11-22 Peptid inhibitorer med urokinase reseptoraktivitet

Country Status (12)

Country Link
US (2) US5656726A (no)
EP (1) EP0745092B1 (no)
JP (2) JPH08510742A (no)
KR (1) KR960702846A (no)
AT (1) ATE182336T1 (no)
AU (1) AU682877B2 (no)
CA (1) CA2163741A1 (no)
DE (1) DE69419623T2 (no)
FI (1) FI955720A0 (no)
NO (1) NO954722D0 (no)
NZ (1) NZ267291A (no)
WO (1) WO1994028014A2 (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
US6248715B1 (en) 1993-06-01 2001-06-19 Chiron Corporation Method of treating a urokinase-type plasminogen activator-mediated disorder
NZ268470A (en) 1993-06-01 1997-09-22 Chiron Corp Production of a peptide containing the egf-like domain of human urokinase-type plasminogen activation (hupa)
EP0842281A1 (en) * 1995-07-31 1998-05-20 Chiron Corporation Peptide analog inhibitors of urokinase receptor activity
US6030940A (en) * 1995-07-31 2000-02-29 Chiron Corporation Peptide analog inhibitors of urokinase receptor activity
US6010699A (en) * 1996-03-15 2000-01-04 Senju Pharmaceutical Co., Ltd. Method for controlling axial length of the eye
US20040204348A1 (en) * 1996-11-12 2004-10-14 The Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5942492A (en) * 1996-11-12 1999-08-24 Angstrom Pharmaceuticals, Inc. Cyclic peptides that bind to urokinase-type plasminogen activator receptor
US6277818B1 (en) * 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
CA2283637C (en) * 1997-03-20 2007-11-13 Fondazione Centro San Raffaele Del Monte Tabor Upar mimicking peptide
US6794358B1 (en) * 1997-03-28 2004-09-21 Brigham And Women's Hospital Peptide ligands of the urokinase receptor
US5994309A (en) * 1997-07-25 1999-11-30 Angstrom Pharmaceuticals, Inc. Anti-invasive and anti-angiogenic compositions and methods
US6291514B1 (en) 1998-02-09 2001-09-18 3-Dimensional Pharmaceuticals, Inc. Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors
CA2346053A1 (en) * 1998-10-02 2000-04-13 Santen Pharmaceutical Co., Ltd. Angiogenesis inhibitor
GB0002366D0 (en) * 2000-02-03 2000-03-22 Astrazeneca Uk Ltd Diagnostic method
US7566765B2 (en) * 2000-03-06 2009-07-28 Rigel Pharmaceuticals, Inc. Heterocyclic compounds containing a nine-membered carbon-nitrogen ring
AU2001264317A1 (en) * 2000-06-20 2002-01-02 Koken Co., Ltd. Preparations for oligonucleotide transfer
US6649597B1 (en) * 2000-06-22 2003-11-18 The University Of Iowa Research Foundation Targeting vector to the urokinase plasminogen activator receptor
CN1313158C (zh) * 2001-06-20 2007-05-02 大日本住友制药株式会社 促进核酸转移的方法
US6908899B2 (en) * 2001-08-17 2005-06-21 U.S. Dept. Of Veterans Affairs Pro-inflammatory fibrinopeptide
CA2468192A1 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Peptidomimetic inhibitors of post-proline cleaving enzymes
WO2003051347A1 (en) * 2001-12-19 2003-06-26 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Use of urokinase receptor antagonists to modulate ischemiareperfusion injury
WO2005061717A1 (ja) * 2003-12-19 2005-07-07 Dainippon Sumitomo Pharma Co., Ltd. 新規な核酸導入法
US20090062184A1 (en) * 2005-03-24 2009-03-05 Dainippon Sumitomo Pharma Co., Ltd. Fine particulate preparation comprising complex of nucleic acid molecule and collagen
TW200813091A (en) * 2006-04-10 2008-03-16 Amgen Fremont Inc Targeted binding agents directed to uPAR and uses thereof
WO2018053350A1 (en) 2016-09-15 2018-03-22 Labcyte Inc. High-efficiency transfection of biological cells using sonoporation
CA3078630A1 (en) 2017-10-12 2019-04-18 Sutrovax, Inc. Periodontitis vaccine and related compositions and method of use
US10770277B2 (en) 2017-11-22 2020-09-08 Labcyte, Inc. System and method for the acoustic loading of an analytical instrument using a continuous flow sampling probe
JP2021515596A (ja) 2018-03-03 2021-06-24 ラブサイト インコーポレイテッド 音響液滴射出を使用して試料から標的部分を抽出するためのシステムおよび方法
EA202192401A1 (ru) 2019-04-02 2022-03-30 Ваксайт, Инк. Оптимизированный бесклеточный синтез плазмидного антигена инвазии в и родственные композиции и способы применения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631270A (en) * 1978-11-20 1986-12-23 Research Corporation Therapeutically useful pseudopeptides, compositions containing the same and methods of preparation and use
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
DK182289D0 (da) * 1989-04-14 1989-04-14 Francesco Blasi Modifikation af proteiner
US5039791A (en) * 1989-11-06 1991-08-13 Monsanto Company Peptide fragments of tissue plasminogen activator
GB2246779B (en) * 1990-08-03 1994-08-17 Delta Biotechnology Ltd Tumour-associated protease inhibitors targeted to tumour cells
JPH07501524A (ja) * 1991-11-18 1995-02-16 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ｕＰＡ−Ｒの検出・分離方法及びｕＰＡのｕＰＡ−Ｒへの結合阻止方法
US5340833A (en) * 1992-05-01 1994-08-23 Eisai Co., Ltd. Urokinase inhibitors

Also Published As

Publication number Publication date
WO1994028014A3 (en) 1995-01-26
CA2163741A1 (en) 1994-12-08
US5656726A (en) 1997-08-12
WO1994028014A2 (en) 1994-12-08
JPH11240897A (ja) 1999-09-07
NZ267291A (en) 1997-09-22
EP0745092A1 (en) 1996-12-04
NO954722L (no) 1995-11-22
ATE182336T1 (de) 1999-08-15
AU6954294A (en) 1994-12-20
FI955720A (fi) 1995-11-27
US5679782A (en) 1997-10-21
DE69419623D1 (de) 1999-08-26
AU682877B2 (en) 1997-10-23
DE69419623T2 (de) 1999-12-02
JPH08510742A (ja) 1996-11-12
EP0745092B1 (en) 1999-07-21
FI955720A0 (fi) 1995-11-27
KR960702846A (ko) 1996-05-23

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