NO951443L - - Google Patents
Info
- Publication number
- NO951443L NO951443L NO951443A NO951443A NO951443L NO 951443 L NO951443 L NO 951443L NO 951443 A NO951443 A NO 951443A NO 951443 A NO951443 A NO 951443A NO 951443 L NO951443 L NO 951443L
- Authority
- NO
- Norway
- Prior art keywords
- aliphatic
- residue
- araliphatic
- cycloaliphatic
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
- C07C255/13—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Forbindelser med formel (I) hvori R1 betyr en alifatlsk, cykloalifatlsk, cykloalifatisk- alifatlsk, aromatisk eller heteroaromatisk rest, en alifatlsk, aralifatlsk eller heteroarylalifatlsk foretret eller med en hydroksybeskyttelsesgruppe beskyttet hydroksygruppe eller en allfatlsk foretret merkaptogruppe og R2 betyr en allfatisk, cykloallfatlsk, cykloallfatlsk- alifatisk, aralifatisk eller heteroarylallfatlsk rest eller R! og R£ utgjør sammen en toverdlg alifatlsk rest, R3 står for eventuelt alifatisk, aralifatisk eller aromatisk forestret karboksy, formyl eller hydroksymetyl, R4 betyr hydrogen, en alifatisk eller arallfatlsk rest eller en aminobeskyttelsesgruppe og R5 betyr hydrogen eller en alifatlsk rest, og deres salter kan anvendes som mellomprodukter for fremstillingen av legemlddelvirkestoffer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH116994 | 1994-04-18 | ||
CH24795 | 1995-01-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO951443D0 NO951443D0 (no) | 1995-04-12 |
NO951443L true NO951443L (no) | 1995-10-19 |
Family
ID=25684018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO951443A NO951443L (no) | 1994-04-18 | 1995-04-12 |
Country Status (10)
Country | Link |
---|---|
US (1) | US5659065A (no) |
EP (1) | EP0678500A1 (no) |
JP (1) | JPH0827079A (no) |
KR (1) | KR950032072A (no) |
AU (1) | AU1642395A (no) |
CA (1) | CA2147044A1 (no) |
FI (1) | FI951773A (no) |
IL (1) | IL113384A0 (no) |
NO (1) | NO951443L (no) |
NZ (1) | NZ270938A (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69410432T2 (de) * | 1993-09-20 | 1998-10-01 | Kanegafuchi Chemical Ind | Verfahren zur herstellung von 3-amino-2-hydroxy-1-propanol-derivaten |
WO2002002500A1 (en) * | 2000-07-03 | 2002-01-10 | Speedel Pharma Ag | Preparation of (r)-2-alkyl-3-phenylpropionic acids |
DE60138099D1 (de) * | 2000-07-05 | 2009-05-07 | Speedel Pharma Ag | Verfahren zur herstellung von substituierten octanoyl-amiden |
CA2412452C (en) * | 2000-07-25 | 2008-12-30 | Speedel Pharma Ag | Process for the preparation of substituted octanoyl amides |
US8168616B1 (en) | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
GB0212410D0 (en) * | 2002-05-29 | 2002-07-10 | Novartis Ag | Organic compounds |
GB0327839D0 (en) * | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
PT1717226E (pt) * | 2004-03-19 | 2009-04-03 | Novartis Ag | Derivados de 5-amino-4-hidroxi-8-(1h-indol-5-il)-octan amida 2,7-substituída como inibidores da renina para o tratamento da hipertensão |
JP4927704B2 (ja) * | 2004-03-19 | 2012-05-09 | シュペーデル・エクスペリメンタ・アーゲー | 有機化合物 |
TW200631929A (en) * | 2004-12-10 | 2006-09-16 | Speedel Experimenta Ag | ω -phenyloctanamides |
GB0511686D0 (en) * | 2005-06-08 | 2005-07-13 | Novartis Ag | Organic compounds |
PL1937248T3 (pl) * | 2005-09-17 | 2010-11-30 | Novartis Ag | Amidy kwasów alkanowych podstawione nasyconymi grupami O-heterocyklicznymi |
GB0521083D0 (en) * | 2005-10-17 | 2005-11-23 | Novartis Ag | Organic compounds |
GB2431643A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431651A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431654A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431652A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431647A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431644A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431650A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431642A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB0605688D0 (en) * | 2006-03-21 | 2006-05-03 | Novartis Ag | Organic compounds |
CN101415413A (zh) * | 2006-04-03 | 2009-04-22 | 诺瓦提斯公司 | 用于治疗高血压的肾素抑制剂 |
CN101679213A (zh) * | 2007-04-03 | 2010-03-24 | 诺瓦提斯公司 | 新方法 |
WO2013171767A1 (en) | 2012-05-18 | 2013-11-21 | Mylan Laboratories Limited | An improved process for the preparation of aliskiren |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH427841A (de) * | 1959-08-24 | 1967-01-15 | Ciba Geigy | Verfahren zur Herstellung von a-(w-Aminoalkyl)-a-aminoessigsäuregruppenhaltigen Peptiden |
US3988341A (en) * | 1974-06-25 | 1976-10-26 | Merck & Co., Inc. | Esterification process |
-
1995
- 1995-04-04 US US08/416,240 patent/US5659065A/en not_active Expired - Fee Related
- 1995-04-07 EP EP95810238A patent/EP0678500A1/de not_active Withdrawn
- 1995-04-12 NO NO951443A patent/NO951443L/no unknown
- 1995-04-12 FI FI951773A patent/FI951773A/fi not_active Application Discontinuation
- 1995-04-12 AU AU16423/95A patent/AU1642395A/en not_active Abandoned
- 1995-04-13 NZ NZ270938A patent/NZ270938A/en unknown
- 1995-04-13 CA CA002147044A patent/CA2147044A1/en not_active Abandoned
- 1995-04-14 IL IL11338495A patent/IL113384A0/xx unknown
- 1995-04-17 KR KR1019950008958A patent/KR950032072A/ko not_active Application Discontinuation
- 1995-04-18 JP JP7092827A patent/JPH0827079A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2147044A1 (en) | 1995-10-19 |
KR950032072A (ko) | 1995-12-20 |
NO951443D0 (no) | 1995-04-12 |
FI951773A (fi) | 1995-10-19 |
IL113384A0 (en) | 1995-07-31 |
US5659065A (en) | 1997-08-19 |
NZ270938A (en) | 1996-11-26 |
AU1642395A (en) | 1995-10-26 |
EP0678500A1 (de) | 1995-10-25 |
FI951773A0 (fi) | 1995-04-12 |
JPH0827079A (ja) | 1996-01-30 |
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