NO941915L - Madikament for nervebeskyttelse - Google Patents
Madikament for nervebeskyttelseInfo
- Publication number
- NO941915L NO941915L NO941915A NO941915A NO941915L NO 941915 L NO941915 L NO 941915L NO 941915 A NO941915 A NO 941915A NO 941915 A NO941915 A NO 941915A NO 941915 L NO941915 L NO 941915L
- Authority
- NO
- Norway
- Prior art keywords
- active ingredient
- drug containing
- medicine
- brain
- drug
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 6
- 239000003814 drug Substances 0.000 title abstract 6
- 210000005036 nerve Anatomy 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 3
- 102000000584 Calmodulin Human genes 0.000 abstract 2
- 108010041952 Calmodulin Proteins 0.000 abstract 2
- 210000004556 brain Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000030833 cell death Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- 206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
Et medikament som inneholder en kalmodulininhibitor som en aktiv bestanddel er beskrevet. Dette medikament kan anvendes for å undertrykke nervecelledød, særlig nervecelledød i hjernen som f.eks. skyldes cerebral ischemi. Et medikament som inneholder en forbindelse som er i stand til å inhibere binding av kalmodulin til et celle- skjelettprotein som en aktiv bestanddel og et medikament som inneholder en forbindelse som undertrykker nedbrytningen av et celleskjelettprotein som en aktiv bestanddel er også be- skrevet. Disse medikamenter kan anvendes i behandlingen og forebygging av forskjellige sykdommer i hjernen og ettersyk- dommer derav, så vel som for å forhindre tilbakefall av disse sykdommer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12293393 | 1993-05-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO941915D0 NO941915D0 (no) | 1994-05-24 |
NO941915L true NO941915L (no) | 1994-11-28 |
Family
ID=14848208
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO941915A NO941915L (no) | 1993-05-25 | 1994-05-24 | Madikament for nervebeskyttelse |
NO993627A NO993627D0 (no) | 1993-05-25 | 1999-07-26 | Anvendelse av en forbindelse for fremstilling av et legemiddel |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO993627A NO993627D0 (no) | 1993-05-25 | 1999-07-26 | Anvendelse av en forbindelse for fremstilling av et legemiddel |
Country Status (10)
Country | Link |
---|---|
US (2) | US5661150A (no) |
EP (1) | EP0627219A1 (no) |
CN (1) | CN1100301A (no) |
AU (2) | AU684270B2 (no) |
CA (1) | CA2124284C (no) |
FI (1) | FI942400A (no) |
NO (2) | NO941915L (no) |
PH (1) | PH31213A (no) |
RU (1) | RU2135162C1 (no) |
TW (1) | TW309427B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0792879B1 (en) * | 1994-11-14 | 2001-02-28 | Daiichi Pharmaceutical Co., Ltd. | Process for preparing 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate |
CA2188816C (en) * | 1996-04-23 | 2009-09-22 | Takeda Chemical Industries, Ltd. | Composition containing .alpha.-fodrin or .alpha.- fodrin fragment protein |
US7202279B1 (en) | 1998-02-11 | 2007-04-10 | Georgetown University | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders |
DE19820224A1 (de) * | 1998-05-06 | 1999-12-09 | Markus Schott | Bindungspartner und Verfahren zur kompetitiven Hemmung der Bindung zwischen NEF-Protein und Calmodulin, sowie Mittel und Verwendung bei HIV-Erkrankungen |
EP1087775B1 (en) | 1998-06-17 | 2005-08-17 | Bristol-Myers Squibb Company | Preventing cerebral infarction through administration of adp-receptor antiplatelet and antihypertensive drugs in combination |
US6105582A (en) * | 1998-07-28 | 2000-08-22 | Pranevicius; Osvaldas | Cerebral blood outflow maintenance during intracranial hypertension |
WO2002010768A2 (en) * | 2000-07-31 | 2002-02-07 | The Regents Of The University Of California | Model for alzheimer's disease and other neurodegenerative diseases |
GB2377635B (en) * | 2001-04-17 | 2005-10-19 | Hoffmann La Roche | Novel use of neuronal calcium sensor-1 (NCS-1) in therapy of CNS disorders and in the development of therapeutic agents |
WO2007062862A2 (en) * | 2005-12-02 | 2007-06-07 | Ludwig Maximilians Universität München | Use of calmodulin inhibitors for the treatment of neurodegenerative disorders |
WO2024018245A1 (en) | 2022-07-22 | 2024-01-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of calpain inhibitors for the treatment of the diabetic kidney disease |
WO2024153744A1 (en) | 2023-01-20 | 2024-07-25 | Institut National de la Santé et de la Recherche Médicale | Autophagy activators for the treatment of rhabdomyolysis |
-
1994
- 1994-05-24 NO NO941915A patent/NO941915L/no unknown
- 1994-05-24 RU RU94017849/14A patent/RU2135162C1/ru not_active IP Right Cessation
- 1994-05-24 EP EP94107994A patent/EP0627219A1/en not_active Withdrawn
- 1994-05-24 FI FI942400A patent/FI942400A/fi unknown
- 1994-05-24 PH PH48319A patent/PH31213A/en unknown
- 1994-05-25 US US08/249,249 patent/US5661150A/en not_active Expired - Fee Related
- 1994-05-25 AU AU63331/94A patent/AU684270B2/en not_active Ceased
- 1994-05-25 CN CN94106239.2A patent/CN1100301A/zh active Pending
- 1994-05-25 TW TW083104733A patent/TW309427B/zh active
- 1994-05-25 CA CA002124284A patent/CA2124284C/en not_active Expired - Fee Related
-
1997
- 1997-03-24 US US08/822,759 patent/US5837706A/en not_active Expired - Fee Related
-
1998
- 1998-03-11 AU AU58372/98A patent/AU5837298A/en not_active Abandoned
-
1999
- 1999-07-26 NO NO993627A patent/NO993627D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
PH31213A (en) | 1998-05-05 |
CN1100301A (zh) | 1995-03-22 |
FI942400A0 (fi) | 1994-05-24 |
TW309427B (no) | 1997-07-01 |
FI942400A (fi) | 1994-11-26 |
AU5837298A (en) | 1998-05-21 |
RU94017849A (ru) | 1997-05-27 |
US5661150A (en) | 1997-08-26 |
US5837706A (en) | 1998-11-17 |
AU6333194A (en) | 1994-12-01 |
EP0627219A1 (en) | 1994-12-07 |
NO941915D0 (no) | 1994-05-24 |
NO993627D0 (no) | 1999-07-26 |
CA2124284A1 (en) | 1994-11-26 |
AU684270B2 (en) | 1997-12-11 |
CA2124284C (en) | 2002-10-01 |
NO993627L (no) | 1994-11-28 |
RU2135162C1 (ru) | 1999-08-27 |
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