NO941150L - Tiadiazinoner - Google Patents
TiadiazinonerInfo
- Publication number
- NO941150L NO941150L NO941150A NO941150A NO941150L NO 941150 L NO941150 L NO 941150L NO 941150 A NO941150 A NO 941150A NO 941150 A NO941150 A NO 941150A NO 941150 L NO941150 L NO 941150L
- Authority
- NO
- Norway
- Prior art keywords
- atoms
- independently
- hal
- thiadiazinone
- tiadiazinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tiadiazinoner med formel hvor R1 og R2 uavhengig av hverandre er H eller A; R3 og R4 uavhengig av hver- andre er -OH, -OA, -S-A, -SO-A, -SO2-A, Hal, metylendioksy, sykloalkyloksy med 3-7 C-atomer eller -O-C.H^.j^F,,; R5 /-N er -NR6R7 eller ~<5:Hj)'" idet en CH2- gruppe også kan være erstattet med oksygen; R6 og R7 uavhengig av hverandre er H eller A; Q er alkylen med 1-6 C- atomer; A er alkyl med 1-6 C-atomer; Hal er F, Cl, Br eller I; m er l, 2, 3, 4, 5 eller 6; n er 3, 4, 5 eller 6; og k er l, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 eller 13; samt fysiologisk aksep- table salter derav. Forbindelsene har fosfodiesterasehemmende virkning og egner seg for bekjempelse av kardio- vaskulære samt astmatiske sykdommer. Fremstillingen av forbindelsene er beskrevet.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4310699A DE4310699A1 (de) | 1993-04-01 | 1993-04-01 | Thiadiazinone |
Publications (2)
Publication Number | Publication Date |
---|---|
NO941150D0 NO941150D0 (no) | 1994-03-29 |
NO941150L true NO941150L (no) | 1994-10-03 |
Family
ID=6484473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO941150A NO941150L (no) | 1993-04-01 | 1994-03-29 | Tiadiazinoner |
Country Status (12)
Country | Link |
---|---|
US (1) | US5434149A (no) |
EP (1) | EP0618201A1 (no) |
JP (1) | JPH072812A (no) |
CN (1) | CN1101644A (no) |
AU (1) | AU675488B2 (no) |
CA (1) | CA2120301A1 (no) |
CZ (1) | CZ70594A3 (no) |
DE (1) | DE4310699A1 (no) |
HU (1) | HUT70543A (no) |
NO (1) | NO941150L (no) |
SK (1) | SK38594A3 (no) |
TW (1) | TW310326B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19500558A1 (de) * | 1995-01-11 | 1996-07-18 | Merck Patent Gmbh | 3-Alkoxycarbonyl-thiadiazinone |
DE19502699A1 (de) * | 1995-01-28 | 1996-08-01 | Merck Patent Gmbh | Arylalkyl-thiadiazinone |
DE19533975A1 (de) * | 1995-09-14 | 1997-03-20 | Merck Patent Gmbh | Arylalkyl-diazinone |
US8153646B2 (en) * | 2000-08-10 | 2012-04-10 | Dart Neuroscience (Cayman) Ltd. | Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation |
AU2001284792A1 (en) * | 2000-08-10 | 2002-02-25 | Cold Spring Harbor Laboratory | Augmented cognitive training |
CA2437932A1 (en) * | 2001-02-12 | 2002-09-19 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Use of type 4 phosphodiesterase inhibitors in myocardial diseases |
DE10150517A1 (de) * | 2001-10-12 | 2003-04-17 | Merck Patent Gmbh | Verwendung von Phosphodiesterase IV-Inhibitoren |
CZ2004516A3 (cs) * | 2001-10-31 | 2004-08-18 | Merckápatentágmbh | Inhibitor fosfodiesterázy typu @Ź jeho kombinace s jinými drogami a jeho použití |
EP1716123A1 (en) * | 2004-02-04 | 2006-11-02 | Altana Pharma AG | Pyridazinone derivatives and their use as pde4 inhibitors |
US7494990B2 (en) | 2004-02-04 | 2009-02-24 | Nycomed Gmbh | 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors |
DE102007041115A1 (de) * | 2007-08-30 | 2009-03-05 | Merck Patent Gmbh | Thiadiazinonderivate |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4413713Y1 (no) * | 1967-04-26 | 1969-06-09 | ||
JPS54135785A (en) * | 1978-04-12 | 1979-10-22 | Yoshitomi Pharmaceut Ind Ltd | Pyridazinone derivative and its preparation |
US4495185A (en) * | 1981-11-12 | 1985-01-22 | Imperial Chemical Industries, Plc | 1,2,4-Triazin-3(2H) ones |
US4489074A (en) * | 1982-11-12 | 1984-12-18 | Imperial Chemical Industries, Plc | 1,3,4-Thiadiazin-2-ones |
EP0478195B1 (en) * | 1990-09-21 | 1999-05-26 | Rohm And Haas Company | Dihydropyridazinones and pyridazinones as fungicides |
-
1993
- 1993-04-01 DE DE4310699A patent/DE4310699A1/de not_active Withdrawn
-
1994
- 1994-03-19 EP EP94104349A patent/EP0618201A1/de not_active Withdrawn
- 1994-03-23 AU AU57983/94A patent/AU675488B2/en not_active Expired - Fee Related
- 1994-03-25 CZ CZ94705A patent/CZ70594A3/cs unknown
- 1994-03-28 JP JP6057099A patent/JPH072812A/ja active Pending
- 1994-03-29 NO NO941150A patent/NO941150L/no unknown
- 1994-03-30 CA CA002120301A patent/CA2120301A1/en not_active Abandoned
- 1994-03-30 TW TW083102744A patent/TW310326B/zh active
- 1994-03-30 CN CN94104074A patent/CN1101644A/zh active Pending
- 1994-03-31 US US08/220,657 patent/US5434149A/en not_active Expired - Fee Related
- 1994-03-31 SK SK385-94A patent/SK38594A3/sk unknown
- 1994-03-31 HU HU9400934A patent/HUT70543A/hu unknown
Also Published As
Publication number | Publication date |
---|---|
CN1101644A (zh) | 1995-04-19 |
NO941150D0 (no) | 1994-03-29 |
CZ70594A3 (en) | 1994-12-15 |
AU5798394A (en) | 1994-10-06 |
JPH072812A (ja) | 1995-01-06 |
AU675488B2 (en) | 1997-02-06 |
DE4310699A1 (de) | 1994-10-06 |
TW310326B (no) | 1997-07-11 |
HUT70543A (en) | 1995-10-30 |
SK38594A3 (en) | 1994-12-07 |
US5434149A (en) | 1995-07-18 |
EP0618201A1 (de) | 1994-10-05 |
HU9400934D0 (en) | 1994-06-28 |
CA2120301A1 (en) | 1994-10-02 |
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