NO940015L - Mikropartikulaere kontrastmidler - Google Patents

Mikropartikulaere kontrastmidler

Info

Publication number
NO940015L
NO940015L NO940015A NO940015A NO940015L NO 940015 L NO940015 L NO 940015L NO 940015 A NO940015 A NO 940015A NO 940015 A NO940015 A NO 940015A NO 940015 L NO940015 L NO 940015L
Authority
NO
Norway
Prior art keywords
contrast agents
microparticulate
microparticulate contrast
microbubble
liquid carrier
Prior art date
Application number
NO940015A
Other languages
English (en)
Norwegian (no)
Other versions
NO940015D0 (no
Inventor
Arne Berg
Jo Klaveness
Per Strande
Lars Stubberud
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26299192&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO940015(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919114565A external-priority patent/GB9114565D0/en
Priority claimed from GB929200386A external-priority patent/GB9200386D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO940015D0 publication Critical patent/NO940015D0/no
Publication of NO940015L publication Critical patent/NO940015L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO940015A 1991-07-05 1994-01-04 Mikropartikulaere kontrastmidler NO940015L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919114565A GB9114565D0 (en) 1991-07-05 1991-07-05 Improvements in or relating to contrast agents
GB929200386A GB9200386D0 (en) 1992-01-09 1992-01-09 Improvements in or relating to contrast agents
PCT/EP1992/001477 WO1993000930A1 (en) 1991-07-05 1992-07-03 Improvements in or relating to contrast agents

Publications (2)

Publication Number Publication Date
NO940015D0 NO940015D0 (no) 1994-01-04
NO940015L true NO940015L (no) 1994-01-04

Family

ID=26299192

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940015A NO940015L (no) 1991-07-05 1994-01-04 Mikropartikulaere kontrastmidler

Country Status (15)

Country Link
US (2) US5607661A (de)
EP (1) EP0593624B1 (de)
JP (1) JPH06510758A (de)
AT (1) ATE151993T1 (de)
AU (1) AU675050B2 (de)
CA (1) CA2112109A1 (de)
DE (1) DE69219337T2 (de)
DK (1) DK0593624T3 (de)
ES (1) ES2103376T3 (de)
FI (1) FI940027A0 (de)
GR (1) GR3023394T3 (de)
HK (1) HK1006945A1 (de)
IE (1) IE80926B1 (de)
NO (1) NO940015L (de)
WO (1) WO1993000930A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
RU2114637C1 (ru) * 1991-09-17 1998-07-10 Сонус Фармасьютикалз, Инк. Биосовместимая контрастная среда и способ получения ультразвукового изображения
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
CZ191695A3 (en) * 1993-01-25 1996-05-15 Sonus Pharma Inc Biologically compatible contrast agent, process of its preparation and representation method by ultrasound
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
PT711179E (pt) 1993-07-30 2005-03-31 Imcor Pharmaceutical Company Composicoes de microbolhas estabilizadas para ultra-som
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
DE19602930A1 (de) * 1996-01-18 1997-07-24 Schering Ag Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
ATE266426T1 (de) * 1996-03-05 2004-05-15 Acusphere Inc Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
GB9622711D0 (en) 1996-10-31 1997-01-08 British Tech Group Instrument having enhanced ultrasound visibility
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles
US20010003580A1 (en) * 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
WO1999042138A1 (en) * 1998-02-19 1999-08-26 University Of Virginia Patent Foundation The use of bjerknes forces to manipulate contrast agents
US7109167B2 (en) 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
WO2002080774A2 (en) * 2001-04-06 2002-10-17 Bracco Research S.A. Method for improved measurement of local physical parameters in afluid-filled cavity
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
WO2004065621A1 (en) 2002-03-01 2004-08-05 Dyax Corp. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
ES2506142T3 (es) 2002-03-01 2014-10-13 Dyax Corp. Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico
US7794693B2 (en) * 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
EP1603935A4 (de) 2003-03-03 2007-03-21 Dyax Corp SPEZIFISCH AN HGF-REZEPTOR (cMet) BINDENDE PEPTIDE UND DEREN VERWENDUNG
SE526838C2 (sv) * 2003-11-27 2005-11-08 Xcounter Ab Undersökningsmetod och anordning för detektion av joniserande strålning
US7019035B2 (en) * 2004-05-17 2006-03-28 Md Scientific Llc Method for attenuating free radical formation resulting from bodily insult
US20050255176A1 (en) * 2004-05-17 2005-11-17 Burgess W P Method for attenuating free radical formation resulting from bodily insult
US20050255175A1 (en) * 2004-05-17 2005-11-17 Burgess W P Method for protecting nephron against injury caused by disruption of a chemical environment in the kidneys
US7625586B2 (en) * 2004-10-28 2009-12-01 Md Scientific, Llc Method for mitigating injury to a kidney resulting from an ischemic event
US7999134B2 (en) * 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using milling
US9827265B1 (en) 2012-04-06 2017-11-28 Md Scientific, Llc Method for attenuating free radical formation resulting from a bodily insult
SG10201913564WA (en) * 2014-08-28 2020-03-30 Massachusetts Gen Hospital Compositions and methods for treatment of neurological disorders
US11471401B2 (en) 2014-08-28 2022-10-18 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
MX2018010220A (es) 2016-02-26 2018-11-29 Massachusetts Gen Hospital Sistemas y metodos de produccion y suministro de suspension medica helada.
JP7211699B2 (ja) * 2017-09-11 2023-01-24 バイエル ファーマ アクチエンゲゼルシャフト 超音波診断用造影剤
US11241330B1 (en) 2021-04-02 2022-02-08 Brixton Biosciences, Inc. Apparatus for creation of injectable slurry

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2680133A (en) * 1951-08-24 1954-06-01 Mallinckrodt Chemical Works Iodine-containing amino-benzoyl derivatives of amino acids
DE2629228C2 (de) * 1976-06-25 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
US4192859A (en) * 1978-09-29 1980-03-11 E. R. Squibb & Sons, Inc. Contrast media containing liposomes as carriers
WO1982001642A1 (en) * 1980-11-17 1982-05-27 Med Inc Ultra Microbubble precursors and methods for their production and use
US4572203A (en) * 1983-01-27 1986-02-25 Feinstein Steven B Contact agents for ultrasonic imaging
DE3313946A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3834705A1 (de) * 1988-10-07 1990-04-12 Schering Ag Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
US5354549A (en) * 1987-07-24 1994-10-11 Nycomed Imaging As Iodinated esters
DE3828905A1 (de) * 1988-08-23 1990-03-15 Schering Ag Mittel bestehend aus cavitate oder clathrate bildenden wirt/gast-komplexen als kontrastmittel
GB8900376D0 (en) * 1989-01-09 1989-03-08 Nycomed As Iodinated esters
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
US5205290A (en) * 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5233995A (en) * 1991-11-21 1993-08-10 Sterling Winthrop Inc. Encapsulated particles useful as contrast agents in ultrasound and x-ray imaging compositions and methods

Also Published As

Publication number Publication date
DE69219337D1 (de) 1997-05-28
FI940027A (fi) 1994-01-04
CA2112109A1 (en) 1993-01-21
DK0593624T3 (da) 1997-05-20
DE69219337T2 (de) 1997-10-09
ES2103376T3 (es) 1997-09-16
US5607661A (en) 1997-03-04
GR3023394T3 (en) 1997-08-29
FI940027A0 (fi) 1994-01-04
HK1006945A1 (en) 1999-03-26
ATE151993T1 (de) 1997-05-15
US5772984A (en) 1998-06-30
NO940015D0 (no) 1994-01-04
AU675050B2 (en) 1997-01-23
WO1993000930A1 (en) 1993-01-21
EP0593624B1 (de) 1997-04-23
EP0593624A1 (de) 1994-04-27
IE80926B1 (en) 1999-06-30
IE922179A1 (en) 1993-01-13
AU2277292A (en) 1993-02-11
JPH06510758A (ja) 1994-12-01

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