NO933690D0 - Nye tiopyranopyrrolderivater og deres fremstilling - Google Patents

Nye tiopyranopyrrolderivater og deres fremstilling

Info

Publication number
NO933690D0
NO933690D0 NO1993933690A NO933690A NO933690D0 NO 933690 D0 NO933690 D0 NO 933690D0 NO 1993933690 A NO1993933690 A NO 1993933690A NO 933690 A NO933690 A NO 933690A NO 933690 D0 NO933690 D0 NO 933690D0
Authority
NO
Norway
Prior art keywords
tiopyranopyr
derivatives
roller
preparation
new
Prior art date
Application number
NO1993933690A
Other languages
English (en)
Norwegian (no)
Other versions
NO933690L (no
Inventor
Daniel Achard
Claude Moutonnier
Jean-Francois Peyronel
Michel Tabart
Alain Truchon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO933690D0 publication Critical patent/NO933690D0/no
Publication of NO933690L publication Critical patent/NO933690L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO933690A 1991-05-17 1993-10-13 Nye tiopyranopyrrolderivater og deres fremstilling NO933690L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9106038A FR2676447B1 (fr) 1991-05-17 1991-05-17 Nouveaux derives du thiopyranopyrrole et leur preparation.
PCT/FR1992/000432 WO1992020686A1 (fr) 1991-05-17 1992-05-15 Nouveaux derives du thiopyranopyrrole et leur preparation

Publications (2)

Publication Number Publication Date
NO933690D0 true NO933690D0 (no) 1993-10-13
NO933690L NO933690L (no) 1993-10-13

Family

ID=9412910

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933690A NO933690L (no) 1991-05-17 1993-10-13 Nye tiopyranopyrrolderivater og deres fremstilling

Country Status (18)

Country Link
US (1) US5484942A (xx)
EP (2) EP0587673A1 (xx)
JP (1) JPH06507895A (xx)
AU (1) AU653032B2 (xx)
CA (1) CA2109295A1 (xx)
CZ (1) CZ245093A3 (xx)
FI (1) FI935074A0 (xx)
FR (1) FR2676447B1 (xx)
HU (1) HUT65590A (xx)
IE (1) IE921544A1 (xx)
IL (1) IL101865A0 (xx)
MX (1) MX9202290A (xx)
NO (1) NO933690L (xx)
NZ (1) NZ242738A (xx)
SK (1) SK126693A3 (xx)
WO (1) WO1992020686A1 (xx)
YU (1) YU51092A (xx)
ZA (1) ZA923516B (xx)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676446B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
US7084152B2 (en) 2000-07-11 2006-08-01 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof
GEP20094640B (en) 2004-07-15 2009-03-10 Bristol Myers Squibb Co Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
EP1904069B1 (en) 2005-07-15 2018-06-13 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
DK2805945T3 (da) 2007-01-10 2019-07-15 Msd Italia Srl Amid-substituerede indazoler som poly(adp-ribose)polymerase- (parp) hæmmere
EP2170076B1 (en) 2007-06-27 2016-05-18 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
EP2413932A4 (en) 2009-04-01 2012-09-19 Merck Sharp & Dohme INHIBITORS OF AKT ACTIVITY
MX2011011907A (es) 2009-05-12 2012-01-20 Albany Molecular Res Inc 7-([1,2,4,]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2, 3,4-tetrahidroisoquinolina y uso de la misma.
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
EP2488028B1 (en) 2009-10-14 2020-08-19 Merck Sharp & Dohme Corp. Substituted piperidines that increase p53 activity and the uses thereof
EP3330377A1 (en) 2010-08-02 2018-06-06 Sirna Therapeutics, Inc. Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
CA2807307C (en) 2010-08-17 2021-02-09 Merck Sharp & Dohme Corp. Rna interference mediated inhibition of hepatitis b virus (hbv) gene expression using short interfering nucleic acid (sina)
US8883801B2 (en) 2010-08-23 2014-11-11 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
EP2613782B1 (en) 2010-09-01 2016-11-02 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
US9242981B2 (en) 2010-09-16 2016-01-26 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel ERK inhibitors
US9260471B2 (en) 2010-10-29 2016-02-16 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
WO2012087772A1 (en) 2010-12-21 2012-06-28 Schering Corporation Indazole derivatives useful as erk inhibitors
CN103732592A (zh) 2011-04-21 2014-04-16 默沙东公司 胰岛素样生长因子-1受体抑制剂
WO2013063214A1 (en) 2011-10-27 2013-05-02 Merck Sharp & Dohme Corp. Novel compounds that are erk inhibitors
EP3919620A1 (en) 2012-05-02 2021-12-08 Sirna Therapeutics, Inc. Short interfering nucleic acid (sina) compositions
CN105050598B (zh) 2012-09-28 2018-04-27 默沙东公司 作为erk抑制剂的新型化合物
HUE035662T2 (en) 2012-11-28 2018-05-28 Merck Sharp & Dohme Compositions and procedures for treating cancer
RU2690663C2 (ru) 2012-12-20 2019-06-05 Мерк Шарп И Доум Корп. Замещенные имидазопиридины в качестве ингибиторов hdm2
EP2951180B1 (en) 2013-01-30 2018-05-02 Merck Sharp & Dohme Corp. 2,6,7,8 substituted purines as hdm2 inhibitors
US20160194368A1 (en) 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Circular polynucleotides
EP3706742B1 (en) 2017-11-08 2023-03-15 Merck Sharp & Dohme LLC Prmt5 inhibitors
US11981701B2 (en) 2018-08-07 2024-05-14 Merck Sharp & Dohme Llc PRMT5 inhibitors
WO2020033282A1 (en) 2018-08-07 2020-02-13 Merck Sharp & Dohme Corp. Prmt5 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
AU502760B2 (en) * 1977-02-28 1979-08-09 Science Union Et Cie, Societe Francaise De Recherche Medicale Azabicycloalkanes and their preparation
DE3260423D1 (en) * 1981-02-17 1984-08-30 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters
US4439229A (en) * 1981-06-29 1984-03-27 Rohm And Haas Company Substituted phthalimides herbicides
US4503043A (en) * 1981-12-07 1985-03-05 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids
JPH0278659A (ja) * 1988-09-12 1990-03-19 Shionogi & Co Ltd アザビシクロアルカン類化合物
FR2676446B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
NZ242738A (en) 1994-07-26
FR2676447B1 (fr) 1993-08-06
JPH06507895A (ja) 1994-09-08
CA2109295A1 (fr) 1992-11-18
FR2676447A1 (fr) 1992-11-20
EP0514276A1 (fr) 1992-11-19
AU653032B2 (en) 1994-09-15
AU1913792A (en) 1992-12-30
SK126693A3 (en) 1994-05-11
ZA923516B (en) 1993-02-24
FI935074A (fi) 1993-11-16
US5484942A (en) 1996-01-16
MX9202290A (es) 1993-02-01
WO1992020686A1 (fr) 1992-11-26
YU51092A (sh) 1994-06-10
EP0587673A1 (fr) 1994-03-23
HU9303251D0 (en) 1994-03-28
IE921544A1 (en) 1992-11-18
IL101865A0 (en) 1992-12-30
NO933690L (no) 1993-10-13
CZ245093A3 (en) 1994-03-16
FI935074A0 (fi) 1993-11-16
HUT65590A (en) 1994-07-28

Similar Documents

Publication Publication Date Title
NO933690D0 (no) Nye tiopyranopyrrolderivater og deres fremstilling
DE59208263D1 (de) 3-Aryl-4-hydroxy-delta3-dihydrofuranon- und 3-Aryl-4-hydroxy-delta3-dihydrothiophenon-Derivate
IS3720A7 (is) Afleiður dialkoxy-pyridinyl-benzimidazole, aðferðvið lögun þeirra og lyfjafræðileg notkun
NO933470L (no) Nye ikke-antikoagulerings-heparinderivater
NO921012D0 (no) Farmasoeytiske preparater og deres anvendelse
DK609489A (da) Imidazolderivater, deres fremstilling og anvendelse
NO943682D0 (no) Imidazol-4-yl-piperidin-derivater, deres fremstilling og terapeutiske anvendelse
NO303446B1 (no) Nye 2-sakkarinylmetylaryl- og -aryloksyacetater, preparater og anvendelse derav
NO914288L (no) Nye 2-sakkarinylmetylarylkarboksylater og fremgangsmaater for deres fremstilling
NO953673L (no) [1,2,4ÅTriazolo[4,3-aÅkinoksalinderivater, deres fremstilling og anvendelse
NO895030L (no) 2-imino-benzotiazolinderivater og deres fremstilling.
NO954763D0 (no) Piperidinderivater, deres fremstilling og anvendelse
ITMI911470A1 (it) N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico
DK45188D0 (da) Substituerede aminderivater og deres anvendelse
NO922934D0 (no) Cykloheksan- og tetrahydropyranderivater
DK73091D0 (da) Quinoxalinforbindelser, deres fremstilling og anvendelse
DK0381135T3 (da) Nye hydroxyperoxider og deres anvendelse
DK469389A (da) Piperidinyl-imidazol-derivater, deres fremstilling og anvendelse
NO971424D0 (no) Nye heterocyklisk substituerte imidazolo-kinoksalidoner, deres fremstilling og anvendelse
NO921908D0 (no) Aminosyreazetidinylsubstituerte pyridonderivater, deres fremstilling og anvendelse som medikamenter
NO922992D0 (no) Imid-terminerte polynitrogenforbindelser, deres fremstilling og anvendelse
NO20003128D0 (no) Nye p-aminofenylderivater og deres anvendelse
NO933596D0 (no) Nye 2-spirocyklopropylcefalosporinsulfonderivater og deres fremstilling
NO942322L (no) Nye 3-halogen-5-halogenmetyl-2-oksazolidinoner og deres anvendelse som mikrobicider
NO982349D0 (no) Nye kinoksalindionderivater, deres fremstilling og anvendelse i legemidler