NO932857D0 - Forbedret blodsubstitutt - Google Patents

Forbedret blodsubstitutt

Info

Publication number
NO932857D0
NO932857D0 NO932857A NO932857A NO932857D0 NO 932857 D0 NO932857 D0 NO 932857D0 NO 932857 A NO932857 A NO 932857A NO 932857 A NO932857 A NO 932857A NO 932857 D0 NO932857 D0 NO 932857D0
Authority
NO
Norway
Prior art keywords
blood substitute
periodate
electrolytes
atp
adenosine
Prior art date
Application number
NO932857A
Other languages
English (en)
Other versions
NO932857L (no
NO308934B1 (no
Inventor
Mario Feola
Jan S Simoni
Original Assignee
Univ Texas Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas Tech filed Critical Univ Texas Tech
Publication of NO932857D0 publication Critical patent/NO932857D0/no
Publication of NO932857L publication Critical patent/NO932857L/no
Publication of NO308934B1 publication Critical patent/NO308934B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6445—Haemoglobin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
NO932857A 1991-02-12 1993-08-11 FremgangsmÕte for fremstilling av et preparat egnet for anvendelse som et blodsubstitutt NO308934B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65476491A 1991-02-12 1991-02-12
PCT/US1991/009384 WO1992013875A1 (en) 1991-02-12 1991-12-13 Improved blood substitute

Publications (3)

Publication Number Publication Date
NO932857D0 true NO932857D0 (no) 1993-08-11
NO932857L NO932857L (no) 1993-10-12
NO308934B1 NO308934B1 (no) 2000-11-20

Family

ID=24626150

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932857A NO308934B1 (no) 1991-02-12 1993-08-11 FremgangsmÕte for fremstilling av et preparat egnet for anvendelse som et blodsubstitutt

Country Status (10)

Country Link
EP (1) EP0586381B1 (no)
JP (1) JP3437572B2 (no)
KR (1) KR100227453B1 (no)
AT (1) ATE173273T1 (no)
AU (1) AU656763B2 (no)
CA (1) CA2103680C (no)
DE (1) DE69130483T2 (no)
FI (1) FI106362B (no)
NO (1) NO308934B1 (no)
WO (1) WO1992013875A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU693354B2 (en) * 1995-04-10 1998-06-25 Baxter International Inc. The use of cross-linked hemoglobin in treating subarachnoid hemorrhage
CA2566874C (en) * 2003-05-15 2014-07-08 Hemosol Lp Targeted delivery of anti-viral compounds through hemoglobin bioconjugation
KR102384708B1 (ko) * 2020-06-19 2022-04-11 대한민국 혈흔형태분석용 인공혈액

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061736A (en) * 1975-02-02 1977-12-06 Alza Corporation Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin
US4401652A (en) * 1980-12-31 1983-08-30 Allied Corporation Process for the preparation of stroma-free hemoglobin solutions
US4473496A (en) * 1981-09-14 1984-09-25 The United States Of America As Represented By The Secretary Of The Army Intramolecularly crosslinked hemoglobin
US4831012A (en) * 1984-03-23 1989-05-16 Baxter International Inc. Purified hemoglobin solutions and method for making same
DE3714351A1 (de) * 1987-04-29 1988-11-17 Barnikol Wolfgang Verfahren zur modifikation, insbesondere zur polymerisation von haemoglobin in vitro
GB8710598D0 (en) * 1987-05-05 1987-06-10 Star Medical Diagnostics Ltd Hemoglobin based blood substitute
US4876241A (en) * 1987-05-22 1989-10-24 Armour Pharmaceutical Company Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
EP0507870B1 (en) * 1989-12-29 1996-04-10 Texas Tech University Health Sciences Center Polyhemoglobin stabilized by purine derivatives and glutathione

Also Published As

Publication number Publication date
WO1992013875A1 (en) 1992-08-20
FI933550A (fi) 1993-08-11
DE69130483D1 (de) 1998-12-17
JP3437572B2 (ja) 2003-08-18
AU1270492A (en) 1992-09-07
DE69130483T2 (de) 1999-06-10
CA2103680A1 (en) 1992-08-20
EP0586381B1 (en) 1998-11-11
NO932857L (no) 1993-10-12
NO308934B1 (no) 2000-11-20
AU656763B2 (en) 1995-02-16
ATE173273T1 (de) 1998-11-15
KR100227453B1 (ko) 1999-11-01
JP2002507185A (ja) 2002-03-05
EP0586381A1 (en) 1994-03-16
FI106362B (fi) 2001-01-31
FI933550A0 (fi) 1993-08-11
EP0586381A4 (en) 1994-09-14
CA2103680C (en) 1999-11-23

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees