NO931803L - TREATMENT OF TISSUE SULKATION - Google Patents

TREATMENT OF TISSUE SULKATION

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Publication number
NO931803L
NO931803L NO93931803A NO931803A NO931803L NO 931803 L NO931803 L NO 931803L NO 93931803 A NO93931803 A NO 93931803A NO 931803 A NO931803 A NO 931803A NO 931803 L NO931803 L NO 931803L
Authority
NO
Norway
Prior art keywords
alkyl
sulkation
tissue
treatment
substituted
Prior art date
Application number
NO93931803A
Other languages
Norwegian (no)
Other versions
NO931803D0 (en
Inventor
Richard E Galardy
Damian Grobelny
Gregory Schultz
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/616,021 external-priority patent/US5114953A/en
Application filed by Univ Florida filed Critical Univ Florida
Publication of NO931803D0 publication Critical patent/NO931803D0/en
Publication of NO931803L publication Critical patent/NO931803L/en

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Abstract

Forbindelser med formlene (1) eller (2) der R1 er H og R2 er alkyl (3-8C) eller der R1 og R2 tatt sammen er -(CH2)n- hvori n - 3-5: R3 er H eller alkyl (1-4C); R4 er en sammensmeltet eller konjugert substituert eller usubstltuert bicykloarylmetylen; X er OR5 eller NER5, der R5 er H eller substituert eller usubstltuert alkyl (1-12C), aryl (6-12C), arylalkyl (6-16C); eller X er et aminosyreresldle eller amld derav; eller X er resldlet til et cyklisk amin eller heterocykllsk arain, er nyttige for behandling eller forhindring av ulkerasjon i vev, særlig kornea.Compounds of formulas (1) or (2) wherein R1 is H and R2 is alkyl (3-8C) or wherein R1 and R2 taken together are - (CH2) n- wherein n - 3-5: R3 is H or alkyl ( 1-4C); R4 is a fused or conjugated substituted or unsubstituted bicycloarylmethylene; X is OR5 or NER5, where R5 is H or substituted or unsubstituted alkyl (1-12C), aryl (6-12C), arylalkyl (6-16C); or X is an amino acid saddle or amide thereof; or X is resiled to a cyclic amine or heterocyclic surface, useful for treating or preventing tissue ulceration, especially cornea.

NO93931803A 1990-11-21 1993-05-18 TREATMENT OF TISSUE SULKATION NO931803L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/616,021 US5114953A (en) 1990-11-21 1990-11-21 Treatment for tissue ulceration
PCT/US1991/008721 WO1992009282A1 (en) 1990-11-21 1991-11-21 Treatment for tissue ulceration

Publications (2)

Publication Number Publication Date
NO931803D0 NO931803D0 (en) 1993-05-18
NO931803L true NO931803L (en) 1993-05-18

Family

ID=26783501

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93931803A NO931803L (en) 1990-11-21 1993-05-18 TREATMENT OF TISSUE SULKATION

Country Status (1)

Country Link
NO (1) NO931803L (en)

Also Published As

Publication number Publication date
NO931803D0 (en) 1993-05-18

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