NO930739L - Substituerte fenylkinazolinderivater - Google Patents
Substituerte fenylkinazolinderivaterInfo
- Publication number
- NO930739L NO930739L NO93930739A NO930739A NO930739L NO 930739 L NO930739 L NO 930739L NO 93930739 A NO93930739 A NO 93930739A NO 930739 A NO930739 A NO 930739A NO 930739 L NO930739 L NO 930739L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- alkyl
- alkoxy
- trifluoromethyl
- substituted phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Substituerte fenylkinazolinderivater med formel I hvor RI er hydrogen, alkyl, alkoksy, trifluormetyl, fluor eller klor, Rs og R2 er uavhengig sv hverandre hydrogen, alkyl, alkoksy, trifluormetyl, fluor eller klor, R- er hydrogen eller alkyl, A og B er enten sammen en gruppe med formelen -C (R-R,)C(R6R7)-S- hvor R4 er hydrogen, alkyl som eventuelt er mono-, di- eller trisubstituert med halogen med atomnummer 9-25, eller fenyl som eventuelt er T.ono- eller disubstituert med alkyl, alkoksy eller ha loger, med atomnummer 9 - 35, Ro er hydroksy og Rt er hydrogen eller R, og Ré danner sammen en dobbelt (r.)-binding, og -;., er hydrogen eller alkyl, eller A er hydrogen og 3 er en gruppe -S-CHR-' -R,c, hvor R,' er hydrogen eller alkyl og R!C er alkyl, alkenyl eller COOR;I hvor R:: er resten av en estergruppe, med den betingelse at RIO er annet enn metyl når R-,' er et hydrogen, RE er hydrogen, alkyl, alkoksy, tri fluormetyl eller halogen med atomnummer 9-35. Fremstilling av forbindelsene er beskrevet. Forbindelsene har terapeutisk aktivitet.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84512392A | 1992-03-03 | 1992-03-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO930739D0 NO930739D0 (no) | 1993-03-01 |
| NO930739L true NO930739L (no) | 1993-09-06 |
Family
ID=25294463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO93930739A NO930739L (no) | 1992-03-03 | 1993-03-01 | Substituerte fenylkinazolinderivater |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0564397A1 (no) |
| JP (1) | JPH0649076A (no) |
| KR (1) | KR930019642A (no) |
| CN (1) | CN1076445A (no) |
| AU (1) | AU3387593A (no) |
| CA (1) | CA2090635A1 (no) |
| CZ (1) | CZ30293A3 (no) |
| FI (1) | FI930922A (no) |
| HU (1) | HUT63629A (no) |
| IL (1) | IL104892A0 (no) |
| NO (1) | NO930739L (no) |
| NZ (1) | NZ247032A (no) |
| TW (1) | TW227563B (no) |
| ZA (1) | ZA931516B (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1655289A1 (en) * | 2004-11-04 | 2006-05-10 | Embl | Quinazoline derivatives, process for their preparation, their use as antimitotics and pharmaceutical compositions comprising said derivatives |
| ME02297B (me) * | 2011-06-10 | 2016-02-20 | Chiesi Farm Spa | Jedinjenja koja imaju aktivnost antagonista muskarinskih receptora i agonist beta2 adrenergičnog receptora |
| CN104119231A (zh) * | 2013-04-27 | 2014-10-29 | 重庆华邦制药有限公司 | 二苯甲胺类化合物的制备方法及中间体 |
| EP3102567B1 (en) * | 2014-02-04 | 2019-07-17 | University of Tennessee Research Foundation | Inhibitors of paxillin function and related compositions and methods |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1242863A (en) * | 1968-05-10 | 1971-08-18 | Pharmacia As | 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF |
| DE3734909A1 (de) * | 1987-10-15 | 1989-04-27 | Boehringer Ingelheim Kg | Verwendung von oxochinazolinderivaten bei der behandlung der hyperlipidaemie |
-
1993
- 1993-02-26 EP EP93810142A patent/EP0564397A1/en not_active Withdrawn
- 1993-02-26 HU HU9300556A patent/HUT63629A/hu unknown
- 1993-03-01 JP JP5062508A patent/JPH0649076A/ja active Pending
- 1993-03-01 IL IL104892A patent/IL104892A0/xx unknown
- 1993-03-01 CZ CZ93302A patent/CZ30293A3/cs unknown
- 1993-03-01 NZ NZ247032A patent/NZ247032A/en unknown
- 1993-03-01 NO NO93930739A patent/NO930739L/no unknown
- 1993-03-01 AU AU33875/93A patent/AU3387593A/en not_active Abandoned
- 1993-03-01 CA CA002090635A patent/CA2090635A1/en not_active Abandoned
- 1993-03-02 FI FI930922A patent/FI930922A/fi not_active Application Discontinuation
- 1993-03-02 KR KR1019930002998A patent/KR930019642A/ko not_active Application Discontinuation
- 1993-03-02 CN CN93102010A patent/CN1076445A/zh active Pending
- 1993-03-03 ZA ZA931516A patent/ZA931516B/xx unknown
- 1993-03-04 TW TW082101580A patent/TW227563B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| ZA931516B (en) | 1994-09-03 |
| KR930019642A (ko) | 1993-10-18 |
| TW227563B (no) | 1994-08-01 |
| HU9300556D0 (en) | 1993-05-28 |
| CZ30293A3 (en) | 1993-12-15 |
| EP0564397A1 (en) | 1993-10-06 |
| JPH0649076A (ja) | 1994-02-22 |
| FI930922A0 (fi) | 1993-03-02 |
| CA2090635A1 (en) | 1993-09-04 |
| CN1076445A (zh) | 1993-09-22 |
| HUT63629A (en) | 1993-09-28 |
| AU3387593A (en) | 1993-09-09 |
| NO930739D0 (no) | 1993-03-01 |
| FI930922A (fi) | 1993-09-04 |
| IL104892A0 (en) | 1993-07-08 |
| NZ247032A (en) | 1994-11-25 |
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