NO920681L - Kinolinholdige ketosyrer som leukotrien-antagonister - Google Patents

Kinolinholdige ketosyrer som leukotrien-antagonister

Info

Publication number
NO920681L
NO920681L NO92920681A NO920681A NO920681L NO 920681 L NO920681 L NO 920681L NO 92920681 A NO92920681 A NO 92920681A NO 920681 A NO920681 A NO 920681A NO 920681 L NO920681 L NO 920681L
Authority
NO
Norway
Prior art keywords
ketosy
quinol
acids
contained
antagonists
Prior art date
Application number
NO92920681A
Other languages
English (en)
Norwegian (no)
Other versions
NO920681D0 (no
Inventor
Michel L Belley
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Publication of NO920681D0 publication Critical patent/NO920681D0/no
Publication of NO920681L publication Critical patent/NO920681L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO92920681A 1991-02-21 1992-02-20 Kinolinholdige ketosyrer som leukotrien-antagonister NO920681L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65893191A 1991-02-21 1991-02-21

Publications (2)

Publication Number Publication Date
NO920681D0 NO920681D0 (no) 1992-02-20
NO920681L true NO920681L (no) 1992-08-24

Family

ID=24643302

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92920681A NO920681L (no) 1991-02-21 1992-02-20 Kinolinholdige ketosyrer som leukotrien-antagonister

Country Status (17)

Country Link
EP (1) EP0500360B1 (fr)
JP (1) JPH0788361B2 (fr)
KR (1) KR920016423A (fr)
CN (1) CN1065062A (fr)
AT (1) ATE154801T1 (fr)
AU (1) AU648385B2 (fr)
CA (1) CA2061675C (fr)
CS (1) CS47192A3 (fr)
DE (1) DE69220517T2 (fr)
ES (1) ES2104821T3 (fr)
FI (1) FI920734A (fr)
HU (1) HU9200552D0 (fr)
IE (1) IE920499A1 (fr)
IL (1) IL100985A0 (fr)
MX (1) MX9200714A (fr)
NO (1) NO920681L (fr)
ZA (1) ZA921232B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270324A (en) * 1992-04-10 1993-12-14 Merck Frosst Canada, Inc. Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
GB9216768D0 (en) * 1992-08-07 1992-09-23 Leo Pharm Prod Ltd Chemical compounds
EP0830133A1 (fr) * 1995-04-28 1998-03-25 Takeda Chemical Industries, Ltd. Composition therapeutique destinee a traiter l'arthrite
WO1998008820A1 (fr) * 1996-08-26 1998-03-05 Yamanouchi Pharmaceutical Co., Ltd. Composes de benzenesulfone et sels de ces derniers
DK1037627T3 (da) * 1998-07-14 2001-10-01 Alcon Lab Inc Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...
CA2563776A1 (fr) * 2004-04-21 2005-11-10 Teva Pharmaceutical Industries Ltd. Procedes de preparation de sodium montelukast
ITMI20050247A1 (it) * 2005-02-18 2006-08-19 Chemi Spa Processo per la preparazione di montelukast
WO2006131782A1 (fr) * 2005-06-07 2006-12-14 Glade Organics Private Limited Procede de preparation de methyl-2-(3-(2-(7-chloro-2-quinolinyl-ethenyl)-phenyl)-3-oxopropyl)benzoate
ES2358923T3 (es) 2005-07-05 2011-05-16 Teva Pharmaceutical Industries, Ltd. Purificación de montelukast.
AR057909A1 (es) * 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar montelukast y compuestos relacionados, que utiliza un compuesto intermediario derivado de un ester sulfonico.
CN101356158B (zh) * 2005-11-18 2011-12-14 斯索恩有限公司 用于制备孟鲁司特的中间体及相关的化合物
NZ575552A (en) * 2006-09-15 2012-02-24 Cipla Ltd Process for the preparation of montelukast, and intermediates therefor
ES2320077B1 (es) 2007-07-31 2010-02-26 Moehs Iberica, S.L. Proceso de preparacion de un antagonista de leucotrienos y de un intermedio del mismo.
CN101851196B (zh) * 2010-05-28 2011-07-27 中国科学院昆明植物研究所 2-(1h)喹啉酮衍生物,其药物组合物及其制备方法和用途
JP6038914B2 (ja) * 2011-07-26 2016-12-07 スン プハルマ アドバンセド リサーチ カンパニー リミテド キノリン−、キノキサリン、又はベンゾチアゾールベースのシステイニルロイコトリエンアンタゴニスト（ｌｔｃ４）

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE59889B1 (en) * 1986-02-14 1994-04-20 Merck Frosst Canada Inc 2-substituted quinoline dioic acids
IL88433A0 (en) * 1987-11-25 1989-06-30 Merck Frosst Canada Inc Diarylstyrylquinoline diacids and pharmaceutical compositions containing them
EP0349062A1 (fr) * 1988-06-27 1990-01-03 Merck Frosst Canada Inc. Acides quinolineétheralkanoiques
NZ233752A (en) * 1989-05-24 1993-05-26 Merck Frosst Canada Inc Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
JPH0525135A (ja) 1993-02-02
ZA921232B (en) 1992-10-28
CN1065062A (zh) 1992-10-07
AU1111992A (en) 1992-08-27
ES2104821T3 (es) 1997-10-16
MX9200714A (es) 1992-10-01
CA2061675C (fr) 2002-12-17
HU9200552D0 (en) 1992-05-28
KR920016423A (ko) 1992-09-24
IL100985A0 (en) 1992-11-15
EP0500360B1 (fr) 1997-06-25
IE920499A1 (en) 1992-08-26
DE69220517D1 (de) 1997-07-31
JPH0788361B2 (ja) 1995-09-27
AU648385B2 (en) 1994-04-21
CS47192A3 (en) 1992-10-14
NO920681D0 (no) 1992-02-20
ATE154801T1 (de) 1997-07-15
EP0500360A1 (fr) 1992-08-26
FI920734A (fi) 1992-08-22
DE69220517T2 (de) 1997-12-18
FI920734A0 (fi) 1992-02-20
CA2061675A1 (fr) 1992-08-22

Similar Documents

Publication Publication Date Title
DK0480717T3 (da) Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister
MX9302033A (es) Acidos de hidroxialquilquinolina fluorados como antagonistas de leucotrieno.
NO920681D0 (no) Kinolinholdige ketosyrer som leukotrien-antagonister
DK0604114T3 (da) 5,6-kondenserende, heterocykliske diarylsyrer som leukotrienantagonister
FI914795A0 (fi) Hydroxialkylkinolinetersyror som leukotrienantagonister.