NO914481L - Fremgangsmaate for fremstilling og anvendelse av substituerte azoler - Google Patents
Fremgangsmaate for fremstilling og anvendelse av substituerte azolerInfo
- Publication number
- NO914481L NO914481L NO91914481A NO914481A NO914481L NO 914481 L NO914481 L NO 914481L NO 91914481 A NO91914481 A NO 91914481A NO 914481 A NO914481 A NO 914481A NO 914481 L NO914481 L NO 914481L
- Authority
- NO
- Norway
- Prior art keywords
- mean
- azols
- substituted
- procedure
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Azoler med formel. der X, Y og Z står for N eller CR, der Rblant annet kan bety hydrogen, klor, metoksy, benzyloksy. L kan blant annet bety -CE-, A betyr en aromatisk eller heterocykllsk rest og T en binding eller en toverdig rest, Ri kan blant annet bety (CR3-C5 )-alkyl og E kan blant annet bety følgende formel. Det blir beskrevet en fremgangsmåte for fremstilling, og midler som inneholder disse forbindelsene og deres anvendelse som helnlngsmiddel.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4036645A DE4036645A1 (de) | 1990-11-16 | 1990-11-16 | Substituierte azole, verfahren zu deren herstellung, deren enthaltende mittel und deren verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
NO914481D0 NO914481D0 (no) | 1991-11-15 |
NO914481L true NO914481L (no) | 1992-05-18 |
Family
ID=6418438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO91914481A NO914481L (no) | 1990-11-16 | 1991-11-15 | Fremgangsmaate for fremstilling og anvendelse av substituerte azoler |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0485929A1 (no) |
JP (1) | JPH04283569A (no) |
KR (1) | KR920009802A (no) |
CN (1) | CN1061410A (no) |
AU (1) | AU8785591A (no) |
BR (1) | BR9104948A (no) |
CA (1) | CA2055636A1 (no) |
CS (1) | CS347091A3 (no) |
DE (1) | DE4036645A1 (no) |
FI (1) | FI915381A (no) |
HU (1) | HUT59673A (no) |
IE (1) | IE913991A1 (no) |
IL (1) | IL100058A0 (no) |
MX (1) | MX9102098A (no) |
NO (1) | NO914481L (no) |
PT (1) | PT99521A (no) |
ZA (1) | ZA919059B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4036706A1 (de) * | 1990-11-17 | 1992-05-21 | Hoechst Ag | Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie |
US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
DE4200954A1 (de) * | 1991-04-26 | 1992-10-29 | Bayer Ag | Heterocyclisch substituierte phenylessigsaeurederivate |
RU2109736C1 (ru) * | 1992-12-17 | 1998-04-27 | Санкио Компани Лимитед | Производные бифенила и способ их получения |
US5300668A (en) * | 1993-03-10 | 1994-04-05 | Pfizer Inc. | Certain esters of 1-(4-X-methylphenyl)cyclopent-3-ene-1-carboxylic acid, wherein X is a trialkylsilyloxy, bromo or hydroxy group, as intermediates |
DE19645313A1 (de) | 1996-11-04 | 1998-05-07 | Basf Ag | Substituierte 3-Benzylpyrazole |
SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
PE20070182A1 (es) | 2005-07-29 | 2007-03-06 | Wyeth Corp | Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona |
PE20070404A1 (es) | 2005-07-29 | 2007-05-10 | Wyeth Corp | Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
US10011637B2 (en) | 2013-06-05 | 2018-07-03 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
WO2023274257A1 (zh) * | 2021-07-01 | 2023-01-05 | 诸葛国琴 | 一种咪唑类化合物、其中间体及应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1329614C (en) * | 1987-05-02 | 1994-05-17 | Rainer Buerstinghaus | N-substituted azoles |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
-
1990
- 1990-11-16 DE DE4036645A patent/DE4036645A1/de not_active Withdrawn
-
1991
- 1991-11-11 EP EP91119186A patent/EP0485929A1/de not_active Withdrawn
- 1991-11-14 BR BR919104948A patent/BR9104948A/pt unknown
- 1991-11-14 FI FI915381A patent/FI915381A/fi unknown
- 1991-11-14 IL IL100058A patent/IL100058A0/xx unknown
- 1991-11-15 MX MX9102098A patent/MX9102098A/es unknown
- 1991-11-15 CS CS913470A patent/CS347091A3/cs unknown
- 1991-11-15 AU AU87855/91A patent/AU8785591A/en not_active Abandoned
- 1991-11-15 JP JP3326662A patent/JPH04283569A/ja active Pending
- 1991-11-15 CA CA002055636A patent/CA2055636A1/en not_active Abandoned
- 1991-11-15 HU HU913583A patent/HUT59673A/hu unknown
- 1991-11-15 PT PT99521A patent/PT99521A/pt not_active Application Discontinuation
- 1991-11-15 IE IE399191A patent/IE913991A1/en not_active Application Discontinuation
- 1991-11-15 NO NO91914481A patent/NO914481L/no unknown
- 1991-11-15 KR KR1019910020341A patent/KR920009802A/ko not_active Application Discontinuation
- 1991-11-15 ZA ZA919059A patent/ZA919059B/xx unknown
- 1991-11-15 CN CN91110736A patent/CN1061410A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
IL100058A0 (en) | 1992-08-18 |
KR920009802A (ko) | 1992-06-25 |
IE913991A1 (en) | 1992-05-20 |
DE4036645A1 (de) | 1992-05-21 |
FI915381A (fi) | 1992-05-17 |
BR9104948A (pt) | 1992-06-23 |
FI915381A0 (fi) | 1991-11-14 |
CN1061410A (zh) | 1992-05-27 |
CS347091A3 (en) | 1992-06-17 |
JPH04283569A (ja) | 1992-10-08 |
HU913583D0 (en) | 1992-01-28 |
AU8785591A (en) | 1992-05-21 |
CA2055636A1 (en) | 1992-05-17 |
PT99521A (pt) | 1992-09-30 |
HUT59673A (en) | 1992-06-29 |
EP0485929A1 (de) | 1992-05-20 |
NO914481D0 (no) | 1991-11-15 |
ZA919059B (en) | 1992-07-29 |
MX9102098A (es) | 1992-07-08 |
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