TW328085B - Novel amino acid derivatives for the treatment or prevention of multi-drug resistance - Google Patents

Novel amino acid derivatives for the treatment or prevention of multi-drug resistance

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Publication number
TW328085B
TW328085B TW083110633A TW83110633A TW328085B TW 328085 B TW328085 B TW 328085B TW 083110633 A TW083110633 A TW 083110633A TW 83110633 A TW83110633 A TW 83110633A TW 328085 B TW328085 B TW 328085B
Authority
TW
Taiwan
Prior art keywords
prevention
treatment
amino acid
acid derivatives
drug resistance
Prior art date
Application number
TW083110633A
Other languages
Chinese (zh)
Inventor
E Zelle Robert
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority to TW083110633A priority Critical patent/TW328085B/en
Application granted granted Critical
Publication of TW328085B publication Critical patent/TW328085B/en

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  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of the formula (I) (I) in which: m is 0; B and D each independently are hydrogen or -(CH2)r-(Z)-(CH2)s-Ar, in which: r is 1-3; s is 0-1; Z is CH2; Ar is selected from the group consisting of free phenyl, 2-pyridyl, 3-pyridyl, 4-pyridyl or imidazolyl; R1 is selected from the group consisting of free (C1-C6) linear or branched alkyl, (C1-C6) linear or branched alkyl substituted by imidazolyl, benzyl, or benzyl substituted by halogen; J is (C1-C6) linear or branched alkyl; K is selected from the group consisting of free (C1-C6) linear or branched alkyl, benzyl, benzyl substituted by halogen; and X is 3,4,5-trimethoxyphenyl.
TW083110633A 1994-11-16 1994-11-16 Novel amino acid derivatives for the treatment or prevention of multi-drug resistance TW328085B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW083110633A TW328085B (en) 1994-11-16 1994-11-16 Novel amino acid derivatives for the treatment or prevention of multi-drug resistance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW083110633A TW328085B (en) 1994-11-16 1994-11-16 Novel amino acid derivatives for the treatment or prevention of multi-drug resistance

Publications (1)

Publication Number Publication Date
TW328085B true TW328085B (en) 1998-03-11

Family

ID=58262388

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083110633A TW328085B (en) 1994-11-16 1994-11-16 Novel amino acid derivatives for the treatment or prevention of multi-drug resistance

Country Status (1)

Country Link
TW (1) TW328085B (en)

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees