NO911777D0 - Hydrazone. - Google Patents
Hydrazone.Info
- Publication number
- NO911777D0 NO911777D0 NO911777A NO911777A NO911777D0 NO 911777 D0 NO911777 D0 NO 911777D0 NO 911777 A NO911777 A NO 911777A NO 911777 A NO911777 A NO 911777A NO 911777 D0 NO911777 D0 NO 911777D0
- Authority
- NO
- Norway
- Prior art keywords
- independently
- hydrogen
- another
- lower alkyl
- hydroxyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
- C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/20—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
- C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
- C07C281/12—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being part of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Photolithography (AREA)
- Wire Bonding (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Compounds of the formula I <IMAGE> in which A denotes a direct bond or -(CH2)n-, in which n represents 1, 2 or 3; X represents a -C(=Y)-NR6R7 radical; Y represents NR8, O or S; Z represents NR9, O or S; R1 and R2, independently of one another, denote hydrogen or one or more substituents other than hydrogen; the radicals R3, R4, R6, R8 and R9 independently of one another denote hydrogen or lower alkyl; and R5 and R7 independently of one another represent hydrogen, lower alkyl, hydroxyl, etherified or esterified hydroxyl or unsubstituted or mono- or disubstituted amino; tautomers thereof, and salts thereof. They have useful pharmaceutical properties and are particularly active against tumours. They are prepared in a manner known per se.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH153890 | 1990-05-07 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO911777D0 true NO911777D0 (en) | 1991-05-06 |
| NO911777L NO911777L (en) | 1991-11-08 |
| NO175097B NO175097B (en) | 1994-05-24 |
| NO175097C NO175097C (en) | 1994-08-31 |
Family
ID=4212764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO911777A NO175097C (en) | 1990-05-07 | 1991-05-06 | Analogous Process for Preparation of Therapeutically Active Hydrazones |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0456133B1 (en) |
| JP (1) | JP2565602B2 (en) |
| KR (1) | KR100203234B1 (en) |
| AT (1) | ATE119878T1 (en) |
| AU (1) | AU645799B2 (en) |
| CA (1) | CA2041832C (en) |
| CY (1) | CY2080B1 (en) |
| CZ (1) | CZ279340B6 (en) |
| DE (1) | DE59104930D1 (en) |
| DK (1) | DK0456133T3 (en) |
| ES (1) | ES2069768T3 (en) |
| FI (1) | FI107916B (en) |
| GR (1) | GR3015574T3 (en) |
| HK (1) | HK1000919A1 (en) |
| HU (1) | HU218221B (en) |
| ID (1) | ID1040B (en) |
| IE (1) | IE66157B1 (en) |
| IL (1) | IL98008A (en) |
| NO (1) | NO175097C (en) |
| NZ (1) | NZ238033A (en) |
| PT (1) | PT97571B (en) |
| RU (2) | RU2057748C1 (en) |
| SA (1) | SA91120283B1 (en) |
| SK (1) | SK279136B6 (en) |
| TW (1) | TW202428B (en) |
| ZA (1) | ZA913391B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5395855A (en) * | 1990-05-07 | 1995-03-07 | Ciba-Geigy Corporation | Hydrazones |
| RU2081108C1 (en) * | 1991-10-16 | 1997-06-10 | Циба-Гейги АГ | Additive salts of acids with the base and pharmaceutical composition showing antitumor activity |
| ES2084459T3 (en) * | 1992-04-03 | 1996-05-01 | Innothera Lab Sa | DERIVATIVES OF INDANO-1,3-DIONA AND INDANO-1,2,3-TRIONA, THEIR PREPARATION PROCEDURES AND THEIR APPLICATION IN THERAPEUTICS. |
| ES2103166B1 (en) * | 1992-08-26 | 1998-04-01 | Ciba Geigy Ag | PROCEDURE FOR OBTAINING BICYCLE AMIDINOHYDRAZONES. |
| FR2710639B1 (en) * | 1993-10-01 | 1995-12-22 | Innothera Lab Sa | Ketone indane derivatives, their process of obtaining, their therapeutic application. |
| CA2210533C (en) * | 1995-01-26 | 2007-12-04 | Novartis Ag | Imidazole derivatives, their preparation and their use as s-adenosylmethionine decarboxylase (=samdc) inhibitors |
| EP1408028A1 (en) * | 2002-10-09 | 2004-04-14 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection |
| EP1834669A1 (en) * | 2006-03-15 | 2007-09-19 | Heinrich-Pette-Institut | Use of specific hydrazone compounds for the treatment of viral infections |
| EP1884515A1 (en) | 2006-07-31 | 2008-02-06 | Laboratorios del Dr. Esteve S.A. | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments |
| CN102627593A (en) * | 2012-02-23 | 2012-08-08 | 河南师范大学 | 1,4-dihydroxy-2-formyl-9,10 anthraquinone thiosemicarbazone new compound with anticancer activity and preparation method thereof |
| PT3164391T (en) * | 2014-07-02 | 2019-10-29 | Inflectis Bioscience | O-alkyl-benzylideneguanidine derivatives and therapeutic use for the treatment of disorders associated an accumulation of misfolded proteins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7407469A (en) * | 1974-06-01 | 1975-12-03 | Akzo Nv | NEW AMIDINOHYDRAZONE COMPOUNDS. |
| DE3416695A1 (en) * | 1984-05-05 | 1985-11-07 | Bayer Ag, 5090 Leverkusen | AMIDINOHYDRAZONE OF TETRALINE, CHROMONE, THIOCHROMONE AND TRETRAHYDROQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS |
| DE68913706T2 (en) * | 1988-12-27 | 1994-08-04 | Du Pont | Substituted semicarbazone arthropodicides. |
-
1991
- 1991-04-26 AU AU75967/91A patent/AU645799B2/en not_active Ceased
- 1991-04-30 IL IL9800891A patent/IL98008A/en not_active IP Right Cessation
- 1991-05-02 TW TW080103460A patent/TW202428B/zh not_active IP Right Cessation
- 1991-05-03 DK DK91107225.4T patent/DK0456133T3/en not_active Application Discontinuation
- 1991-05-03 NZ NZ238033A patent/NZ238033A/en unknown
- 1991-05-03 EP EP91107225A patent/EP0456133B1/en not_active Expired - Lifetime
- 1991-05-03 ES ES91107225T patent/ES2069768T3/en not_active Expired - Lifetime
- 1991-05-03 AT AT91107225T patent/ATE119878T1/en not_active IP Right Cessation
- 1991-05-03 CA CA002041832A patent/CA2041832C/en not_active Expired - Lifetime
- 1991-05-03 FI FI912164A patent/FI107916B/en active
- 1991-05-03 DE DE59104930T patent/DE59104930D1/en not_active Expired - Fee Related
- 1991-05-06 NO NO911777A patent/NO175097C/en not_active IP Right Cessation
- 1991-05-06 HU HU519/91A patent/HU218221B/en not_active IP Right Cessation
- 1991-05-06 CZ CS911317A patent/CZ279340B6/en not_active IP Right Cessation
- 1991-05-06 IE IE153091A patent/IE66157B1/en not_active IP Right Cessation
- 1991-05-06 RU SU914895338A patent/RU2057748C1/en active
- 1991-05-06 PT PT97571A patent/PT97571B/en not_active IP Right Cessation
- 1991-05-06 SK SK1317-91A patent/SK279136B6/en not_active IP Right Cessation
- 1991-05-06 KR KR1019910007285A patent/KR100203234B1/en not_active IP Right Cessation
- 1991-05-06 ZA ZA913391A patent/ZA913391B/en unknown
- 1991-05-07 JP JP3101512A patent/JP2565602B2/en not_active Expired - Fee Related
- 1991-12-17 SA SA91120283A patent/SA91120283B1/en unknown
-
1992
- 1992-01-30 ID IDP189692A patent/ID1040B/en unknown
- 1992-10-23 RU RU9292004359A patent/RU2066311C1/en active
-
1995
- 1995-03-30 GR GR950400746T patent/GR3015574T3/en unknown
-
1997
- 1997-11-06 HK HK97102109A patent/HK1000919A1/en not_active IP Right Cessation
-
1998
- 1998-10-16 CY CY9802080A patent/CY2080B1/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |