NO905620L - Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater.

Info

Publication number
NO905620L
NO905620L NO90905620A NO905620A NO905620L NO 905620 L NO905620 L NO 905620L NO 90905620 A NO90905620 A NO 90905620A NO 905620 A NO905620 A NO 905620A NO 905620 L NO905620 L NO 905620L
Authority
NO
Norway
Prior art keywords
alkyl
preparation
hydroxy
protected
procedure
Prior art date
Application number
NO90905620A
Other languages
English (en)
Norwegian (no)
Other versions
NO905620D0 (no
Inventor
Norihiko Shimazaki
Hitoshi Yamazaki
Takumi Yatabe
Hirokazu Tanaka
Yoshikuni Itoh
Masashi Hashimoto
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909000014A external-priority patent/GB9000014D0/en
Priority claimed from GB909025065A external-priority patent/GB9025065D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO905620D0 publication Critical patent/NO905620D0/no
Publication of NO905620L publication Critical patent/NO905620L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO90905620A 1990-01-02 1990-12-28 Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater. NO905620L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909000014A GB9000014D0 (en) 1990-01-02 1990-01-02 Quinazoline derivatives and their preparation
GB909025065A GB9025065D0 (en) 1990-11-19 1990-11-19 Quinazoline derivatives and their preparation

Publications (2)

Publication Number Publication Date
NO905620D0 NO905620D0 (no) 1990-12-28
NO905620L true NO905620L (no) 1991-07-03

Family

ID=26296447

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90905620A NO905620L (no) 1990-01-02 1990-12-28 Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater.

Country Status (13)

Country Link
US (1) US5264438A (hu)
EP (1) EP0436157B1 (hu)
JP (1) JPH0578349A (hu)
KR (1) KR910014368A (hu)
CN (1) CN1053063A (hu)
AT (1) ATE126796T1 (hu)
AU (1) AU635099B2 (hu)
CA (1) CA2033363A1 (hu)
DE (1) DE69021855T2 (hu)
HU (1) HU208131B (hu)
IE (1) IE904580A1 (hu)
NO (1) NO905620L (hu)
PT (1) PT96404A (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202318A (en) * 1990-05-14 1993-04-13 Syntex (U.S.A.) Inc. Tricyclic compounds acting at serotonin receptor subtypes
JPH06510538A (ja) * 1991-09-06 1994-11-24 藤沢薬品工業株式会社 キナゾリン誘導体およびそれらの製造方法
GB9127532D0 (en) * 1991-12-31 1992-02-19 Fujisawa Pharmaceutical Co A novel use of a quinazoline derivative
GB9205702D0 (en) * 1992-03-16 1992-04-29 Fujisawa Pharmaceutical Co A new use of a quinazoline derivative
FR2723091B1 (fr) * 1994-07-29 1996-11-08 Esteve Labor Dr Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
CA2245586A1 (en) * 1996-02-06 1997-08-14 Japan Tobacco Inc. Novel compounds and pharmaceutical use thereof
AU5679398A (en) * 1997-01-31 1998-08-25 Kyowa Hakko Kogyo Co. Ltd. Piperidine derivatives
US6521630B1 (en) * 1999-08-31 2003-02-18 Pfizer Inc. Tetrahydroquinazoline-2,4-diones and therapeutic uses thereof
DE102004020908A1 (de) 2004-04-28 2005-11-17 Grünenthal GmbH Substituierte 5,6,7,8,-Tetrahydro-pyrido[4,3-d]pyrimidin-2-yl- und 5,6,7,8,-Tetrahydro-chinazolin-2-yl-Verbindungen
US20080275058A1 (en) * 2005-09-15 2008-11-06 Korea Research Institute Of Chemical Technology N-Substituted-1H-Quinoline-2,4-Diones, Preparation Method Thereof, And Pharmaceutical Composition Containing The Same
US20090203708A1 (en) * 2006-07-05 2009-08-13 Korea Research Institute Of Chemical Technology Novel substituted-1-h-quinazoline-2,4-dione derivatives, preparation method thereof and pharmaceutical composition containing the same
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
CN103739596A (zh) * 2013-12-10 2014-04-23 刘磊 用于心脑血管疾病的喹唑啉衍生物
CN106146413B (zh) * 2015-04-03 2019-01-18 中南大学 2,4-(1h,3h)-喹唑啉二酮衍生物及其合成方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274194A (en) * 1963-03-29 1966-09-20 Miles Lab Quinazolinedione derivatives
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation

Also Published As

Publication number Publication date
CA2033363A1 (en) 1991-07-03
IE904580A1 (en) 1991-07-03
US5264438A (en) 1993-11-23
EP0436157B1 (en) 1995-08-23
ATE126796T1 (de) 1995-09-15
EP0436157A1 (en) 1991-07-10
DE69021855T2 (de) 1996-02-29
CN1053063A (zh) 1991-07-17
JPH0578349A (ja) 1993-03-30
HU208131B (en) 1993-08-30
KR910014368A (ko) 1991-08-31
AU635099B2 (en) 1993-03-11
AU6820790A (en) 1991-07-04
NO905620D0 (no) 1990-12-28
DE69021855D1 (de) 1995-09-28
PT96404A (pt) 1991-10-15
HUT56089A (en) 1991-07-29

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