NO903832L - Aminosyrederivater. - Google Patents

Aminosyrederivater.

Info

Publication number
NO903832L
NO903832L NO90903832A NO903832A NO903832L NO 903832 L NO903832 L NO 903832L NO 90903832 A NO90903832 A NO 90903832A NO 903832 A NO903832 A NO 903832A NO 903832 L NO903832 L NO 903832L
Authority
NO
Norway
Prior art keywords
amino acid
acid derivative
derivative
amino
acid
Prior art date
Application number
NO90903832A
Other languages
English (en)
Norwegian (no)
Other versions
NO903832D0 (no
Inventor
Quirico Branca
Werner Neidhart
Henri Ramuz
Heinz Stadler
Wolfgang Wostl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO903832D0 publication Critical patent/NO903832D0/no
Publication of NO903832L publication Critical patent/NO903832L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/25—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO90903832A 1989-09-04 1990-09-03 Aminosyrederivater. NO903832L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH319289 1989-09-04
CH233690 1990-07-12

Publications (2)

Publication Number Publication Date
NO903832D0 NO903832D0 (no) 1990-09-03
NO903832L true NO903832L (no) 1991-03-05

Family

ID=25690187

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90903832A NO903832L (no) 1989-09-04 1990-09-03 Aminosyrederivater.

Country Status (14)

Country Link
US (1) US5688946A (fr)
EP (1) EP0416373A3 (fr)
JP (1) JPH0399047A (fr)
KR (1) KR910006224A (fr)
AU (1) AU646640B2 (fr)
CA (1) CA2023099A1 (fr)
FI (1) FI904360A0 (fr)
HU (1) HUT58060A (fr)
IE (1) IE903197A1 (fr)
IL (1) IL95503A0 (fr)
MC (1) MC2151A1 (fr)
NO (1) NO903832L (fr)
NZ (1) NZ235057A (fr)
PT (1) PT95192A (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5275950A (en) * 1990-05-11 1994-01-04 Abbott Laboratories Process for the preparation of a renin inhibiting compound
IE68045B1 (en) * 1990-05-11 1996-05-15 Abbott Lab Renin inhibitors
US5278161A (en) * 1990-06-28 1994-01-11 Hoffmann-La Roche Inc. Amino acid derivatives useful as renin inhibitors
DE4040056A1 (de) * 1990-12-14 1992-06-17 Merck Patent Gmbh Saeureamide
TW198712B (fr) 1991-04-17 1993-01-21 Hoffmann La Roche
US5268361A (en) * 1991-06-07 1993-12-07 Sri International Hydroxyazido derivatives and related compounds as renin inhibitors
CA2095671A1 (fr) * 1992-06-04 1993-12-05 Quirico Branca Derives d'acide amine
US5317039A (en) * 1992-07-20 1994-05-31 G. D. Searle & Co. Cyclopropyl-alanine aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
US5268391A (en) * 1992-07-20 1993-12-07 C. D. Searle & Co. Propargyl-terminated cycloalkylalkyl-P2-site substituted aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5246969A (en) * 1992-07-20 1993-09-21 G. D. Searle & Co. Di-propargyl-containing aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
US5314920A (en) * 1992-07-20 1994-05-24 G. D. Searle & Co. Ethynyl-alanine aryl/alkylsulfonyl-terminated amino-diol compounds for treatment of hypertension
US5212185A (en) * 1992-08-14 1993-05-18 G. D. Searle & Co. Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5312838A (en) * 1992-09-21 1994-05-17 G. D. Searle & Co. β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
ES2100109B1 (es) * 1993-07-14 1998-02-16 Squibb & Sons Inc Inhibidores de proteasas de aminodiol.
US5414018A (en) * 1993-09-24 1995-05-09 G. D. Searle & Co. Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension
US5416119A (en) * 1993-10-25 1995-05-16 G. D. Searle & Co. Alkylaminoalkyl-terminated sulfide/sulfonyl-containing cycloalkyl-alanine amino-diol compounds for treatment of hypertension
US5432201A (en) * 1993-11-22 1995-07-11 G. D. Searle & Co. Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension
IL140499A0 (en) * 1998-07-06 2002-02-10 Guilford Pharm Inc Nalladase inhibitors useful as pharmaceutical compounds and compositions
CA2360740A1 (fr) * 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Composes utiles en tant qu'inhibiteurs reversibles de la cathepsine s
JP2002201168A (ja) * 2000-12-28 2002-07-16 Kaken Pharmaceut Co Ltd シクロヘキサン誘導体
WO2002062850A2 (fr) * 2001-02-02 2002-08-15 Millennium Pharmaceuticals, Inc. Anticorps hybrides et leurs utilisations
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
UA108742C2 (uk) 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
WO2015049239A1 (fr) * 2013-10-04 2015-04-09 Solvay Specialty Polymers Italy S.P.A. Procédé de synthèse de sels de sulfonate de fluoralkyle
WO2018053446A1 (fr) * 2016-09-18 2018-03-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Inhibiteurs de yap1 ciblant l'interaction de yap1 avec oct4

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
US4845079A (en) * 1985-01-23 1989-07-04 Luly Jay R Peptidylaminodiols
JPS63503380A (ja) * 1986-01-16 1988-12-08 アボット・ラボラトリーズ ペプチド類似体
NZ218937A (en) * 1986-01-16 1990-03-27 Abbott Lab Functionalised peptidyl aminodiols and -triols as renin inhibitors and pharmaceutical compositions
US4726941A (en) * 1986-01-23 1988-02-23 Regents Of The University Of Minnesota Acylated cyanamide composition for treating ethanol ingestion
US5032577A (en) * 1986-12-31 1991-07-16 Abbott Laboratories Peptidylaminodiols
EP0309766B1 (fr) * 1987-09-29 1998-04-15 Banyu Pharmaceutical Co., Ltd. Dérivés N-acylés d'aminoacides et leur utilisation
EP0313847A3 (fr) * 1987-10-01 1989-11-29 G.D. Searle & Co. Alpha-succinamidoacyl aminodiols non peptidiques comme agents anti-hypertensifs
CA1328333C (fr) * 1988-03-04 1994-04-05 Quirico Branca Derives d'acide amine
TW225540B (fr) * 1990-06-28 1994-06-21 Shionogi & Co
ZA917693B (en) * 1990-09-27 1992-05-27 Merck & Co Inc Fibrinogen receptor antagonists

Also Published As

Publication number Publication date
HUT58060A (en) 1992-01-28
CA2023099A1 (fr) 1991-03-05
AU646640B2 (en) 1994-03-03
NZ235057A (en) 1994-12-22
IE903197A1 (en) 1991-03-13
AU6136090A (en) 1991-03-07
EP0416373A3 (en) 1992-05-27
IL95503A0 (en) 1991-06-30
JPH0399047A (ja) 1991-04-24
PT95192A (pt) 1991-05-22
EP0416373A2 (fr) 1991-03-13
FI904360A0 (fi) 1990-09-04
US5688946A (en) 1997-11-18
HU905676D0 (en) 1991-03-28
MC2151A1 (fr) 1992-03-10
NO903832D0 (no) 1990-09-03
KR910006224A (ko) 1991-04-27

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