NO903390L - Fremgangsmaate for fremstilling av 2,3-dihydro-1-(pyridinylamino)-indoler og deres anvendelse som legemidler. - Google Patents
Fremgangsmaate for fremstilling av 2,3-dihydro-1-(pyridinylamino)-indoler og deres anvendelse som legemidler.Info
- Publication number
- NO903390L NO903390L NO90903390A NO903390A NO903390L NO 903390 L NO903390 L NO 903390L NO 90903390 A NO90903390 A NO 90903390A NO 903390 A NO903390 A NO 903390A NO 903390 L NO903390 L NO 903390L
- Authority
- NO
- Norway
- Prior art keywords
- loweralkyl
- aryl
- pyridinylamino
- indoles
- dihydro
- Prior art date
Links
- -1 PYRIDINYLAMINO Chemical class 0.000 title abstract 7
- 239000003814 drug Substances 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000006513 pyridinyl methyl group Chemical group 0.000 abstract 2
- 125000005301 thienylmethyl group Chemical group [H]C1=C([H])C([H])=C(S1)C([H])([H])* 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- UPQBWVOMAKRBQF-UHFFFAOYSA-N n-pyridin-2-yl-2,3-dihydroindol-1-amine Chemical class C1CC2=CC=CC=C2N1NC1=CC=CC=N1 UPQBWVOMAKRBQF-UHFFFAOYSA-N 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38841589A | 1989-08-02 | 1989-08-02 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO903390D0 NO903390D0 (no) | 1990-08-01 |
| NO903390L true NO903390L (no) | 1991-02-04 |
| NO176398B NO176398B (no) | 1994-12-19 |
| NO176398C NO176398C (no) | 1995-03-29 |
Family
ID=23534038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO903390A NO176398C (no) | 1989-08-02 | 1990-08-01 | Analogifremgangsmåte for fremstilling av terapeutisk aktive 2,3-dihydro-1-(pyridinylamino)-indoler |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0415103B1 (no) |
| JP (1) | JPH0674266B2 (no) |
| KR (1) | KR0164595B1 (no) |
| AT (1) | ATE118002T1 (no) |
| AU (1) | AU628201B2 (no) |
| CA (1) | CA2022488C (no) |
| DE (1) | DE69016531T2 (no) |
| DK (1) | DK0415103T3 (no) |
| ES (1) | ES2068294T3 (no) |
| FI (1) | FI95466C (no) |
| GR (1) | GR3015228T3 (no) |
| IE (1) | IE66601B1 (no) |
| IL (1) | IL95251A (no) |
| NO (1) | NO176398C (no) |
| NZ (1) | NZ234726A (no) |
| PT (1) | PT94880B (no) |
| ZA (1) | ZA906048B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868190A (en) * | 1988-12-27 | 1989-09-19 | Hoechst-Roussel Pharmaceuticals, Inc. | N-pyridinyl-9H-carbazol-9-amines |
| US5214038A (en) * | 1991-04-15 | 1993-05-25 | Hoechst-Roussel Pharmaceuticals Inc. | 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the preparation thereof |
| US5202319A (en) * | 1991-09-23 | 1993-04-13 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines |
| US5459274A (en) * | 1994-05-13 | 1995-10-17 | Hoechst-Roussel Pharmaceuticals Inc. | Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines |
| US6100276A (en) * | 1996-04-12 | 2000-08-08 | Aventis Pharmaceuticals Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
| WO1998029407A2 (en) * | 1996-12-27 | 1998-07-09 | Hoechst Marion Roussel, Inc. | N-(pyridinylamino)isoindolines for treating alzheimer's and depression |
| GB0119435D0 (en) | 2001-02-15 | 2001-10-03 | Aventis Pharm Prod Inc | Method of treating of demyelinating diseases or conditions |
| KR20230062159A (ko) | 2021-10-29 | 2023-05-09 | 대우조선해양 주식회사 | 극지용 선박의 발전기 엔진의 외기 흡입구조 및 상기 외기 흡입구조를 포함하는 극지용 선박 |
| KR20230062160A (ko) | 2021-10-29 | 2023-05-09 | 대우조선해양 주식회사 | 극지용 선박의 공조 시스템 및 상기 극지용 선박의 외기 흡입구조 |
| KR20230062158A (ko) | 2021-10-29 | 2023-05-09 | 대우조선해양 주식회사 | 극지용 선박의 발전기 엔진의 외기 흡입구조 및 상기 외기 흡입구조를 포함하는 극지용 선박 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3852335T2 (de) * | 1987-04-24 | 1995-05-11 | Hoechst Roussel Pharma | N-(Pyridinyl)-1H-indol-1-amine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel. |
| US4868190A (en) * | 1988-12-27 | 1989-09-19 | Hoechst-Roussel Pharmaceuticals, Inc. | N-pyridinyl-9H-carbazol-9-amines |
| US4983615A (en) * | 1989-06-28 | 1991-01-08 | Hoechst-Roussel Pharmaceuticals Inc. | Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders |
-
1990
- 1990-07-31 NZ NZ234726A patent/NZ234726A/en unknown
- 1990-07-31 FI FI903820A patent/FI95466C/fi not_active IP Right Cessation
- 1990-07-31 EP EP90114661A patent/EP0415103B1/en not_active Expired - Lifetime
- 1990-07-31 DK DK90114661.3T patent/DK0415103T3/da active
- 1990-07-31 ES ES90114661T patent/ES2068294T3/es not_active Expired - Lifetime
- 1990-07-31 AT AT90114661T patent/ATE118002T1/de not_active IP Right Cessation
- 1990-07-31 IL IL9525190A patent/IL95251A/en not_active IP Right Cessation
- 1990-07-31 DE DE69016531T patent/DE69016531T2/de not_active Expired - Fee Related
- 1990-08-01 IE IE278890A patent/IE66601B1/en not_active IP Right Cessation
- 1990-08-01 ZA ZA906048A patent/ZA906048B/xx unknown
- 1990-08-01 CA CA002022488A patent/CA2022488C/en not_active Expired - Fee Related
- 1990-08-01 PT PT94880A patent/PT94880B/pt not_active IP Right Cessation
- 1990-08-01 AU AU60003/90A patent/AU628201B2/en not_active Ceased
- 1990-08-01 JP JP2202619A patent/JPH0674266B2/ja not_active Expired - Fee Related
- 1990-08-01 NO NO903390A patent/NO176398C/no unknown
- 1990-08-01 KR KR1019900011817A patent/KR0164595B1/ko not_active Expired - Fee Related
-
1995
- 1995-02-28 GR GR950400433T patent/GR3015228T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL95251A (en) | 1996-08-04 |
| FI95466C (fi) | 1996-02-12 |
| PT94880B (pt) | 1997-12-31 |
| DE69016531T2 (de) | 1995-07-06 |
| IE66601B1 (en) | 1996-01-24 |
| AU6000390A (en) | 1991-02-07 |
| JPH0674266B2 (ja) | 1994-09-21 |
| ZA906048B (en) | 1991-05-29 |
| FI903820A0 (fi) | 1990-07-31 |
| KR0164595B1 (ko) | 1999-01-15 |
| PT94880A (pt) | 1991-04-18 |
| EP0415103B1 (en) | 1995-02-01 |
| NO903390D0 (no) | 1990-08-01 |
| ATE118002T1 (de) | 1995-02-15 |
| IE902788A1 (en) | 1991-02-27 |
| DK0415103T3 (da) | 1995-06-19 |
| FI95466B (fi) | 1995-10-31 |
| EP0415103A1 (en) | 1991-03-06 |
| JPH03118378A (ja) | 1991-05-20 |
| GR3015228T3 (en) | 1995-05-31 |
| NZ234726A (en) | 1992-01-29 |
| CA2022488C (en) | 2000-11-07 |
| KR910004598A (ko) | 1991-03-29 |
| AU628201B2 (en) | 1992-09-10 |
| ES2068294T3 (es) | 1995-04-16 |
| NO176398C (no) | 1995-03-29 |
| CA2022488A1 (en) | 1991-02-03 |
| NO176398B (no) | 1994-12-19 |
| DE69016531D1 (de) | 1995-03-16 |
| IL95251A0 (en) | 1991-06-10 |
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