NO903386L - Fremgangsmaate for fremstilling av 4-(n-substituert amino)-2-butynyl-1-karbamater og -tiokarbamater og derivater derav. - Google Patents
Fremgangsmaate for fremstilling av 4-(n-substituert amino)-2-butynyl-1-karbamater og -tiokarbamater og derivater derav.Info
- Publication number
- NO903386L NO903386L NO90903386A NO903386A NO903386L NO 903386 L NO903386 L NO 903386L NO 90903386 A NO90903386 A NO 90903386A NO 903386 A NO903386 A NO 903386A NO 903386 L NO903386 L NO 903386L
- Authority
- NO
- Norway
- Prior art keywords
- carbamates
- butynyl
- thio
- derivatives
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/388,777 US4996201A (en) | 1989-08-02 | 1989-08-02 | 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO903386D0 NO903386D0 (no) | 1990-08-01 |
| NO903386L true NO903386L (no) | 1991-02-04 |
Family
ID=23535470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO90903386A NO903386L (no) | 1989-08-02 | 1990-08-01 | Fremgangsmaate for fremstilling av 4-(n-substituert amino)-2-butynyl-1-karbamater og -tiokarbamater og derivater derav. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4996201A (ko) |
| EP (1) | EP0411616A1 (ko) |
| JP (1) | JPH0374376A (ko) |
| KR (1) | KR910004550A (ko) |
| AU (1) | AU6001890A (ko) |
| CA (1) | CA2022511A1 (ko) |
| FI (1) | FI903834A0 (ko) |
| IE (1) | IE902791A1 (ko) |
| NO (1) | NO903386L (ko) |
| PT (1) | PT94873A (ko) |
| ZA (1) | ZA906056B (ko) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5409948A (en) * | 1992-11-23 | 1995-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating cognitive disorders with phenserine |
| US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
| US5468875A (en) * | 1994-12-22 | 1995-11-21 | American Home Products Corporation | 1-azabicycloheptane derivatives |
| WO1997017348A1 (en) * | 1995-11-08 | 1997-05-15 | American Home Products Corporation | 1-azabicycloheptane derivatives and their pharmaceutical use |
| US5773458A (en) * | 1996-10-30 | 1998-06-30 | American Home Products Corporation | 1-azabicycloheptane derivatives |
| US20050182044A1 (en) * | 2004-02-17 | 2005-08-18 | Bruinsma Gosse B. | Combinatorial therapy with an acetylcholinesterase inhibitor and (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate |
| CA2508585A1 (en) * | 2004-06-01 | 2005-12-01 | Axonyx, Inc. | Transdermal delivery system for treatment of cognitive disorders |
| WO2005123068A2 (en) * | 2004-06-08 | 2005-12-29 | Axonyx, Inc. | Methods of dealying alzheimer’s disease progression using a beta-amyloid precursor protein inhibitor and a hmg coa reductase inhibitor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3131213A (en) * | 1957-05-21 | 1964-04-28 | Sterling Drug Inc | 2, 6-dimethyl and 2, 6-diethylphenyl n-(aminoalkyl) carbamates and acid addition salts thereof |
| US4065471A (en) * | 1965-04-09 | 1977-12-27 | Sterling Drug Inc. | N-(4-Amino-2-butynyl)imides |
| US3354178A (en) * | 1965-04-09 | 1967-11-21 | Sterling Drug Inc | Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides |
| US3452031A (en) * | 1967-07-21 | 1969-06-24 | Parke Davis & Co | Aminoalkylcarbamate esters |
| DE2515146A1 (de) * | 1975-04-08 | 1976-10-21 | Bayer Ag | Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1989
- 1989-08-02 US US07/388,777 patent/US4996201A/en not_active Expired - Fee Related
-
1990
- 1990-07-31 AU AU60018/90A patent/AU6001890A/en not_active Abandoned
- 1990-08-01 IE IE279190A patent/IE902791A1/en unknown
- 1990-08-01 CA CA002022511A patent/CA2022511A1/en not_active Abandoned
- 1990-08-01 NO NO90903386A patent/NO903386L/no unknown
- 1990-08-01 KR KR1019900011932A patent/KR910004550A/ko not_active Application Discontinuation
- 1990-08-01 FI FI903834A patent/FI903834A0/fi not_active Application Discontinuation
- 1990-08-01 JP JP2202621A patent/JPH0374376A/ja active Pending
- 1990-08-01 PT PT94873A patent/PT94873A/pt not_active Application Discontinuation
- 1990-08-01 ZA ZA906056A patent/ZA906056B/xx unknown
- 1990-08-01 EP EP90114788A patent/EP0411616A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR910004550A (ko) | 1991-03-28 |
| JPH0374376A (ja) | 1991-03-28 |
| NO903386D0 (no) | 1990-08-01 |
| ZA906056B (en) | 1992-04-29 |
| US4996201A (en) | 1991-02-26 |
| FI903834A0 (fi) | 1990-08-01 |
| AU6001890A (en) | 1991-02-07 |
| CA2022511A1 (en) | 1991-02-03 |
| PT94873A (pt) | 1991-04-18 |
| EP0411616A1 (en) | 1991-02-06 |
| IE902791A1 (en) | 1991-02-27 |
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