NO902861L - Naftylamino- og naftyloksypyridinaminer og beslektede forbindelser og fremgangsmaate for fremstilling derav. - Google Patents
Naftylamino- og naftyloksypyridinaminer og beslektede forbindelser og fremgangsmaate for fremstilling derav.Info
- Publication number
- NO902861L NO902861L NO90902861A NO902861A NO902861L NO 902861 L NO902861 L NO 902861L NO 90902861 A NO90902861 A NO 90902861A NO 902861 A NO902861 A NO 902861A NO 902861 L NO902861 L NO 902861L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- naphythyloxypyridamines
- naftylamino
- procedures
- preparing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 101100294102 Caenorhabditis elegans nhr-2 gene Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Det er beskrevet forbindelser av formelen. hvor. X er 0 eller NR, Rer hydrogen, laverealkyl eller. laverealkylkarbonyl,. Y er hydrogen, laverealkyl, laverealkoksy, halogen. eller trifluormetyl,. Z er KOeller NHE, hvor R er hydrogen, laverealkyl,. aryllaverealkyl eller laverealkylkarbonyl, og. n er 0 eller 1, under den forutsetning at n er 0 når Z. er NHR,. og en fremgangsmåte for fremstilling av forbindelsene.Forbindelsene er nyttige som topiske antiinflamma-torlske midler for behandling av hudsykdommer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90/002767A US4931457B1 (en) | 1989-06-28 | 1989-06-28 | Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
NO902861D0 NO902861D0 (no) | 1990-06-27 |
NO902861L true NO902861L (no) | 1991-01-02 |
Family
ID=23468431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO90902861A NO902861L (no) | 1989-06-28 | 1990-06-27 | Naftylamino- og naftyloksypyridinaminer og beslektede forbindelser og fremgangsmaate for fremstilling derav. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4931457B1 (no) |
EP (1) | EP0405426A3 (no) |
JP (1) | JPH0338567A (no) |
KR (1) | KR910000647A (no) |
AU (1) | AU5784790A (no) |
CA (1) | CA2019624A1 (no) |
FI (1) | FI903214A0 (no) |
IE (1) | IE902330A1 (no) |
IL (1) | IL94876A0 (no) |
NO (1) | NO902861L (no) |
PT (1) | PT94502A (no) |
ZA (1) | ZA905001B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3837809A1 (de) * | 1988-11-08 | 1990-05-10 | Merck Patent Gmbh | Tetralinderivate |
TW200462B (no) * | 1990-09-27 | 1993-02-21 | Hoechst Roussel Pharma | |
US5581010A (en) * | 1994-07-22 | 1996-12-03 | Rockwell International Corporation | Semi-organic crystals for nonlinear optical devices |
RU2203272C2 (ru) * | 1997-02-21 | 2003-04-27 | Байер Акциенгезелльшафт | Замещенные бициклические соединения, исходные и промежуточные продукты для их получения и фармацевтическая композиция на их основе |
DE19740785A1 (de) * | 1997-02-21 | 1998-08-27 | Bayer Ag | Arylsulfonamide und Analoga |
EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3118884A (en) * | 1959-10-19 | 1964-01-21 | Schering Corp | Derivatives of 3-azaphenothiazine and 3-azaphenoxazine |
US3495969A (en) * | 1967-09-25 | 1970-02-17 | Mobil Oil Corp | Substituted nitropyridines as herbicides |
US3576616A (en) * | 1969-05-15 | 1971-04-27 | Monsanto Co | Herbicidal compositions and methods |
US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
EP0000816A1 (en) * | 1977-08-06 | 1979-02-21 | Beecham Group Plc | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them |
GB2073736B (en) * | 1979-10-03 | 1984-02-01 | Ici Ltd | Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof |
US4521426A (en) * | 1982-09-30 | 1985-06-04 | Union Carbide Corporation | Pesticidal bicyclooxyheterocyclyl aroyl ureas |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
-
1989
- 1989-06-28 US US90/002767A patent/US4931457B1/en not_active Expired - Lifetime
-
1990
- 1990-06-26 EP EP19900112087 patent/EP0405426A3/en not_active Withdrawn
- 1990-06-26 FI FI903214A patent/FI903214A0/fi not_active Application Discontinuation
- 1990-06-26 KR KR1019900009441A patent/KR910000647A/ko not_active Application Discontinuation
- 1990-06-26 IL IL94876A patent/IL94876A0/xx unknown
- 1990-06-27 AU AU57847/90A patent/AU5784790A/en not_active Abandoned
- 1990-06-27 IE IE233090A patent/IE902330A1/en unknown
- 1990-06-27 NO NO90902861A patent/NO902861L/no unknown
- 1990-06-27 ZA ZA905001A patent/ZA905001B/xx unknown
- 1990-06-27 JP JP2166946A patent/JPH0338567A/ja active Pending
- 1990-06-27 PT PT94502A patent/PT94502A/pt not_active Application Discontinuation
- 1990-06-27 CA CA002019624A patent/CA2019624A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US4931457B1 (en) | 1993-11-16 |
EP0405426A2 (en) | 1991-01-02 |
IE902330A1 (en) | 1991-01-16 |
JPH0338567A (ja) | 1991-02-19 |
IE902330L (en) | 1990-12-28 |
NO902861D0 (no) | 1990-06-27 |
CA2019624A1 (en) | 1990-12-28 |
KR910000647A (ko) | 1991-01-29 |
AU5784790A (en) | 1991-01-03 |
US4931457A (en) | 1990-06-05 |
PT94502A (pt) | 1991-02-08 |
EP0405426A3 (en) | 1992-05-13 |
IL94876A0 (en) | 1991-04-15 |
FI903214A0 (fi) | 1990-06-26 |
ZA905001B (en) | 1991-03-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI890931A (fi) | Menetelmä 5-lipoksigenaasia inhiboivien 4-(4-fenyyli-1-piperatsinyyli)fenoleiden valmistamiseksi | |
DE60037892D1 (de) | Nitroimidazolpräparationen zur äusseren anwendung zur behandlung von atopischer dermatitis | |
NO170280C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive sulfamatderivater | |
GEP20032913B (en) | Thienylazolylalcoxyethanamines, Their Preparation and Their Application as Medicaments | |
NO902861L (no) | Naftylamino- og naftyloksypyridinaminer og beslektede forbindelser og fremgangsmaate for fremstilling derav. | |
ES2123652T3 (es) | 7-(2-aminoetil)-benzotiazolonas. | |
NO885714L (no) | Fremgangsmaate for fremstilling av propoksybenzenderivater. | |
NO913331L (no) | 4-substituerte dihydropyrido(4,3-d)pyrimidiner for behandling av hudforstyrrelser. | |
ES2032501T3 (es) | Un procedimiento de preparacion de derivados de urileno-2,4,6-triamino-3-oxido. | |
JPS5424872A (en) | Imidazole derivatives, their preparation, and agricultural and horticultural fungicides | |
ES2016305B3 (es) | Compuestos de piperazina, procedimiento para prepararlos y composicion farmaceutica y su uso. | |
DK0420224T3 (da) | Anthihepatopatisk middel | |
AR246511A1 (es) | Acido 2-azabiciclo (2.2.1)hept-5-eno-2-acetico y derivados del mismo, procedimiento para su preparacion y procedimiento para preparar n-fosfonometilglicina con los mismos. | |
NO303686B1 (no) | Forbindelse til anvendelse ved fremstilling av alkylderivater av trazodon med CNS-aktivitet | |
ATE181503T1 (de) | Verwendung von idazoxan und derivaten zur herstellung eines arzneimittels zur behandlung von parkinsonismus und seiner evolution | |
DE69619088T2 (de) | Quinoxalin-Derivate zur Behandlung von Tinnitus | |
ATE121623T1 (de) | Verwendung von quinazolinen zur herstellung eines arzneimittels zur behandlung und vorbeugung von arrhythmie. | |
ATE81465T1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. | |
ATE81466T1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur prophylaxe und zur behandlung von herzinsuffizienz. | |
JPS5239674A (en) | Imidazole derivatives and agricultural bactericides therefrom | |
JPS532473A (en) | N-3-pyridyl-n#-phenylamidine derivatives, method of preparing same, and fungicides for agriculture and gardening use | |
TH893EX (th) | การเตรียมอนุพันธ์ของเบนซิมิดาโซลและสารผสมของสารเหล่านี้ | |
TH893A (th) | การเตรียมอนุพันธ์ของเบนซิมิดาโซลและสารผสมของสารเหล่านี้ | |
TH4659EX (th) | เพอร์ไฮโดรไธอะเซฟีนและอนุพันธ์ต่างๆ ของเพอร์ไฮโดรอะเซฟีน การเตรียมและการใช้สารเหล่านี้สำหรับรักษาโรค | |
TH2131B (th) | การเตรียมอนุพันธ์ของเบนซิมิดาโซลและสารผสมของสารเหล่านี้ |