NO902607L - Krystallinske cefem-syreaddisjonssalter og fremgangsmaate for fremstilling derav. - Google Patents

Krystallinske cefem-syreaddisjonssalter og fremgangsmaate for fremstilling derav.

Info

Publication number
NO902607L
NO902607L NO90902607A NO902607A NO902607L NO 902607 L NO902607 L NO 902607L NO 90902607 A NO90902607 A NO 90902607A NO 902607 A NO902607 A NO 902607A NO 902607 L NO902607 L NO 902607L
Authority
NO
Norway
Prior art keywords
preparing
crystalline
acid addition
addition salts
cefem
Prior art date
Application number
NO90902607A
Other languages
English (en)
Other versions
NO174258C (no
NO174258B (no
NO902607D0 (no
Inventor
Fiedhelm Adam
Walter Duerckheimer
Burkhard Mencke
Dieter Isert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO902607D0 publication Critical patent/NO902607D0/no
Publication of NO902607L publication Critical patent/NO902607L/no
Publication of NO174258B publication Critical patent/NO174258B/no
Publication of NO174258C publication Critical patent/NO174258C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO902607A 1989-06-13 1990-06-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive, krystallinske cefemsyreaddisjonssalter NO174258C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3919259A DE3919259A1 (de) 1989-06-13 1989-06-13 Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
NO902607D0 NO902607D0 (no) 1990-06-12
NO902607L true NO902607L (no) 1990-12-14
NO174258B NO174258B (no) 1993-12-27
NO174258C NO174258C (no) 1994-04-06

Family

ID=6382651

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902607A NO174258C (no) 1989-06-13 1990-06-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive, krystallinske cefemsyreaddisjonssalter

Country Status (19)

Country Link
US (1) US5409918A (no)
EP (1) EP0402806B1 (no)
JP (1) JPH0730085B2 (no)
KR (1) KR0158883B1 (no)
CN (1) CN1043043C (no)
AT (1) ATE95185T1 (no)
AU (1) AU645254B2 (no)
CA (1) CA2018794C (no)
DE (2) DE3919259A1 (no)
DK (1) DK0402806T3 (no)
ES (1) ES2045653T3 (no)
FI (1) FI96424C (no)
HU (1) HU207087B (no)
IE (1) IE64076B1 (no)
IL (1) IL94701A (no)
NO (1) NO174258C (no)
NZ (1) NZ234004A (no)
PT (1) PT94347B (no)
ZA (1) ZA904526B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU48484B (sh) * 1991-05-24 1998-09-18 Hoechst Aktiengesellschaft Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline
US5589593A (en) * 1991-11-11 1996-12-31 Biochimica Opos Spa Crystalline form of a cephalosporin antibiotic
TW212181B (no) * 1992-02-14 1993-09-01 Hoechst Ag
ES2117066T3 (es) * 1992-05-21 1998-08-01 Hoechst Ag Procedimiento para la disociacion de esteres profarmacos de cefalosporina para dar acido 7-amino-3-metoximetil-cef-3-em-4-carboxilico.
LT3871B (en) 1993-11-30 1996-04-25 Hoechst Ag Additive crystalline salts of pure diastereomers of 1-cefem-4-carboxylic acid 1-(2,2-dimethyl-propionyloxy)ethyl esters, process for the preparation thereof, pharmaceutical compositions and process for the preparation thereof
AT401651B (de) * 1994-06-14 1996-11-25 Biochemie Gmbh 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroximinoacetamido)-3-n,n- dimethylcarbamoyloxymethyl-3-cephem-4-
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
JP4749194B2 (ja) * 2006-03-28 2011-08-17 ジャパンパイル株式会社 オーガー削孔装置における土質試料採取具

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
JPS5760345B2 (no) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
US4668783A (en) * 1974-12-19 1987-05-26 Takeda Chemical Industries, Ltd. Thiazolylacetamido cephalosporin compounds
JPS523091A (en) * 1975-06-23 1977-01-11 Takeda Chem Ind Ltd A prcess for preparing cephalosporins
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
IT1101437B (it) * 1978-11-28 1985-09-28 Proter Spa Procedimento per il recupero di cefaloridina da soluzione acquosa nella quale e'stata prodotta
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
FR2532315A1 (fr) * 1982-08-27 1984-03-02 Rhone Poulenc Sante Formes cristallisees de sels d'addition avec des acides, de l'((amino-2-thiazolyl-4)-2 methoxyimino-2 acetamido)-7 carboxy-2 (dioxo-5,6 formylmethyl-4 tetrahydro-1,4,5,6 triazine-1,2,4 yl-3) thio-2 vinyl)-3 oxo-8 thia-5 aza-1 bicyclo(4.2.0) octene-2 isomere syn, forme e et leur preparation
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
DE3804841A1 (de) * 1988-02-17 1989-08-31 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
DE3809561A1 (de) * 1988-03-22 1989-10-05 Hoechst Ag Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil

Also Published As

Publication number Publication date
JPH0730085B2 (ja) 1995-04-05
FI96424B (fi) 1996-03-15
IL94701A0 (en) 1991-04-15
FI96424C (fi) 1996-06-25
EP0402806B1 (de) 1993-09-29
KR910000748A (ko) 1991-01-30
KR0158883B1 (ko) 1998-12-01
PT94347A (pt) 1991-02-08
NZ234004A (en) 1992-07-28
HU903828D0 (en) 1990-11-28
IE64076B1 (en) 1995-07-12
ES2045653T3 (es) 1994-01-16
JPH0324086A (ja) 1991-02-01
CA2018794C (en) 2000-05-16
AU5697690A (en) 1990-12-20
DE59002880D1 (de) 1993-11-04
ZA904526B (en) 1991-03-27
NO174258C (no) 1994-04-06
IE902115L (en) 1990-12-13
DE3919259A1 (de) 1990-12-20
AU645254B2 (en) 1994-01-13
IL94701A (en) 1994-11-28
US5409918A (en) 1995-04-25
FI902900A0 (fi) 1990-06-11
PT94347B (pt) 1997-01-31
NO174258B (no) 1993-12-27
CA2018794A1 (en) 1990-12-13
NO902607D0 (no) 1990-06-12
CN1048042A (zh) 1990-12-26
HUT56375A (en) 1991-08-28
CN1043043C (zh) 1999-04-21
IE902115A1 (en) 1991-01-02
HU207087B (en) 1993-03-01
EP0402806A1 (de) 1990-12-19
DK0402806T3 (da) 1994-01-17
ATE95185T1 (de) 1993-10-15

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