NO902301L - Fremgangsmaate for fremstilling av diarylstyrylkinolin-disyrer. - Google Patents
Fremgangsmaate for fremstilling av diarylstyrylkinolin-disyrer.Info
- Publication number
- NO902301L NO902301L NO90902301A NO902301A NO902301L NO 902301 L NO902301 L NO 902301L NO 90902301 A NO90902301 A NO 90902301A NO 902301 A NO902301 A NO 902301A NO 902301 L NO902301 L NO 902301L
- Authority
- NO
- Norway
- Prior art keywords
- disyres
- diarylstyrylqinoline
- procedure
- preparation
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
- Detergent Compositions (AREA)
- Steroid Compounds (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35647889A | 1989-05-24 | 1989-05-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO902301D0 NO902301D0 (no) | 1990-05-23 |
NO902301L true NO902301L (no) | 1990-11-26 |
Family
ID=23401598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO90902301A NO902301L (no) | 1989-05-24 | 1990-05-23 | Fremgangsmaate for fremstilling av diarylstyrylkinolin-disyrer. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0399818B1 (fr) |
JP (1) | JPH07103107B2 (fr) |
KR (1) | KR900018035A (fr) |
AT (1) | ATE126509T1 (fr) |
AU (1) | AU5581190A (fr) |
CA (1) | CA2017376C (fr) |
DE (1) | DE69021639T2 (fr) |
FI (1) | FI902555A0 (fr) |
IL (1) | IL94484A0 (fr) |
NO (1) | NO902301L (fr) |
NZ (1) | NZ233752A (fr) |
PT (1) | PT94129A (fr) |
ZA (1) | ZA903983B (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3927930A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate |
CA2053216C (fr) | 1990-10-12 | 2003-04-08 | Michel L. Belley | Derives acides d'hyroxyalkylquinoline saturee comme antagonistes des leucotrienes |
CA2053209C (fr) * | 1990-10-12 | 1998-12-08 | Michel L. Belley | Derives acides d'hydroxyalkylquinoline insaturee comme antagonistes des leucotrienes |
US5266568A (en) * | 1990-10-12 | 1993-11-30 | Merck Frosst Canada, Inc. | Hydroxyalkylquinoline ether acids as leukotriene antagonists |
US5856322A (en) * | 1990-10-12 | 1999-01-05 | Merck Frosst Canada, Inc. | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
DE69113735T2 (de) * | 1990-10-12 | 1996-06-13 | Merck Frosst Canada Inc | Hydroxyalkylchinolin Äther Säure als Leukotrien-Antagoniste. |
IE920499A1 (en) * | 1991-02-21 | 1992-08-26 | Merck Frosst Canada Inc | Quinoline-containing ketoacids as leukotriene antagonists |
EP0575494A1 (fr) * | 1991-03-13 | 1993-12-29 | Smithkline Beecham Corporation | Antagonistes des leucotrienes |
US5149703A (en) * | 1991-09-06 | 1992-09-22 | Merck Frosst Canada, Inc. | Quinoline-substituted chromans and related compounds as leukotriene antagonists |
US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
US5438141A (en) * | 1993-05-21 | 1995-08-01 | Merck Frosst Canada, Inc. | Heteroaryl and haloaryl quinoline derivatives of cyclopropaneacetic acid as leukotriene antagonists |
ES2080656B1 (es) * | 1993-07-19 | 1996-10-16 | Merck Frosst Canada Inc | Acidos de hidroxialquilquinolina fluorados como antagonistas del leucotrieno. |
US5750539A (en) * | 1995-06-07 | 1998-05-12 | Merck Frosst Canada | Heteroaryl diol acids as leukotriene antagonists |
US5668150A (en) * | 1996-07-26 | 1997-09-16 | Abbott Laboratories | Non-symmetrical bis-heteroarylmethoxyphenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
US6310211B1 (en) | 1996-09-10 | 2001-10-30 | Pharmacia & Upjohn Company | 8-hydroxy-7-substituted quinolines as anti-viral agents |
US5783586A (en) * | 1996-10-01 | 1998-07-21 | Abbott Laboratories | Heteroarylmethoxyphenylthioalkyl carboxylates as inhibitors of leukotriene biosynthesis |
SG91339A1 (en) | 2000-03-08 | 2002-09-17 | Givaudan Sa | Organoleptic compositions |
US6492396B2 (en) * | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
JPWO2003030937A1 (ja) * | 2001-10-05 | 2005-01-20 | 小野薬品工業株式会社 | ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤 |
WO2007022946A1 (fr) | 2005-08-21 | 2007-03-01 | Abbott Gmbh & Co. Kg | Composes heterocycliques et leur utilisation en tant que partenaires de liaison des recepteurs 5-ht5 |
JP6038914B2 (ja) * | 2011-07-26 | 2016-12-07 | スン プハルマ アドバンセド リサーチ カンパニー リミテド | キノリン−、キノキサリン、又はベンゾチアゾールベースのシステイニルロイコトリエンアンタゴニスト(ltc4) |
AU2014225550C1 (en) | 2013-03-08 | 2017-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof |
CN105814022B (zh) * | 2013-12-09 | 2018-09-28 | Ucb生物制药私人有限公司 | 作为tnf活性调节剂的稠合的二环杂芳族衍生物 |
WO2019094856A1 (fr) | 2017-11-13 | 2019-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibiteurs atypiques de transporteurs de monoamine ; leur procédé de production et d'utilisation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
US4732978A (en) * | 1985-10-03 | 1988-03-22 | American Home Products Corporation | Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents |
IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
EP0271287A3 (fr) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Acides quinoléine dicarboxyliques et leurs amides |
IL88433A0 (en) * | 1987-11-25 | 1989-06-30 | Merck Frosst Canada Inc | Diarylstyrylquinoline diacids and pharmaceutical compositions containing them |
-
1990
- 1990-05-21 NZ NZ233752A patent/NZ233752A/xx unknown
- 1990-05-23 AU AU55811/90A patent/AU5581190A/en not_active Abandoned
- 1990-05-23 DE DE69021639T patent/DE69021639T2/de not_active Expired - Fee Related
- 1990-05-23 CA CA002017376A patent/CA2017376C/fr not_active Expired - Fee Related
- 1990-05-23 FI FI902555A patent/FI902555A0/fi not_active IP Right Cessation
- 1990-05-23 PT PT94129A patent/PT94129A/pt not_active Application Discontinuation
- 1990-05-23 ZA ZA903983A patent/ZA903983B/xx unknown
- 1990-05-23 IL IL94484A patent/IL94484A0/xx unknown
- 1990-05-23 EP EP90305640A patent/EP0399818B1/fr not_active Expired - Lifetime
- 1990-05-23 NO NO90902301A patent/NO902301L/no unknown
- 1990-05-23 AT AT90305640T patent/ATE126509T1/de not_active IP Right Cessation
- 1990-05-24 JP JP2132754A patent/JPH07103107B2/ja not_active Expired - Lifetime
- 1990-05-24 KR KR1019900007608A patent/KR900018035A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ233752A (en) | 1993-05-26 |
ATE126509T1 (de) | 1995-09-15 |
FI902555A0 (fi) | 1990-05-23 |
DE69021639D1 (de) | 1995-09-21 |
AU5581190A (en) | 1990-12-13 |
DE69021639T2 (de) | 1996-02-15 |
EP0399818A1 (fr) | 1990-11-28 |
IL94484A0 (en) | 1991-03-10 |
JPH0372459A (ja) | 1991-03-27 |
CA2017376C (fr) | 2000-07-18 |
NO902301D0 (no) | 1990-05-23 |
KR900018035A (ko) | 1990-12-20 |
ZA903983B (en) | 1991-03-27 |
PT94129A (pt) | 1991-02-08 |
EP0399818B1 (fr) | 1995-08-16 |
JPH07103107B2 (ja) | 1995-11-08 |
CA2017376A1 (fr) | 1990-11-24 |
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