NO875381L - Renininhibitorer. - Google Patents

Renininhibitorer.

Info

Publication number
NO875381L
NO875381L NO875381A NO875381A NO875381L NO 875381 L NO875381 L NO 875381L NO 875381 A NO875381 A NO 875381A NO 875381 A NO875381 A NO 875381A NO 875381 L NO875381 L NO 875381L
Authority
NO
Norway
Prior art keywords
renin
renin inhibitors
hyperaldosteronism
methods
peptides
Prior art date
Application number
NO875381A
Other languages
English (en)
Other versions
NO875381D0 (no
Inventor
James Perry Hudspeth
James Stanley Kaltenbronn
Joseph Thomas Repine
William Howard Roark
Francis John Tinney
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO875381D0 publication Critical patent/NO875381D0/no
Publication of NO875381L publication Critical patent/NO875381L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Oppfinnelsen angår nye renin-hemmende peptider so» kan brukes for behandling av reninforbundet hypertensjon, hyperaldosteronisme og forskjellig* typer hjertesvikt. Det er beskrevet fremgangsmåter for fremstilling av peptidene, preparater og blandinger son inneholder disse, samt fremgangsmåter for deres bruk. Videre inngår en diagnostisk fremgangsmåte hvor man bruker forbindelsene for å bestemme nmrvaret av reninforbundet hypertensjon eller hyperaldosteronisme.
NO875381A 1986-12-23 1987-12-22 Renininhibitorer. NO875381L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94558286A 1986-12-23 1986-12-23
US11327887A 1987-11-02 1987-11-02

Publications (2)

Publication Number Publication Date
NO875381D0 NO875381D0 (no) 1987-12-22
NO875381L true NO875381L (no) 1988-06-24

Family

ID=26810877

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875381A NO875381L (no) 1986-12-23 1987-12-22 Renininhibitorer.

Country Status (8)

Country Link
EP (1) EP0275480A3 (no)
AU (1) AU616875B2 (no)
DK (1) DK673787A (no)
FI (1) FI875603A (no)
NO (1) NO875381L (no)
NZ (1) NZ222755A (no)
PH (1) PH25913A (no)
PT (1) PT86450B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY103189A (en) * 1986-10-31 1993-05-29 Pfizer Nor-statine and nor-cyclostatine polypeptides
US4895834A (en) * 1986-12-15 1990-01-23 Warner-Lambert Company Renin inhibitors III
DE3839128A1 (de) * 1988-11-19 1990-05-31 Hoechst Ag Renin-hemmende dipeptide, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
US5550262A (en) * 1994-11-14 1996-08-27 Cephalon, Inc. Multicatalytic protease inhibitors
US5614649A (en) * 1994-11-14 1997-03-25 Cephalon, Inc. Multicatalytic protease inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114993B1 (en) * 1982-12-27 1990-05-16 Merck & Co. Inc. Renin inhibitory tripeptides
SU1676454A3 (ru) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Способ получени пептидов или их фармацевтически приемлемых солей
EP0184855A3 (en) * 1984-12-14 1989-05-03 Abbott Laboratories Resin inhibiting compounds
FR2585708B1 (fr) * 1985-07-31 1989-07-07 Sanofi Sa Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique
PT82077B (fr) * 1985-02-26 1987-09-25 Sanofi Sa Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides

Also Published As

Publication number Publication date
EP0275480A2 (en) 1988-07-27
FI875603A0 (fi) 1987-12-18
EP0275480A3 (en) 1990-03-28
AU8247087A (en) 1988-07-07
NZ222755A (en) 1989-11-28
DK673787A (da) 1988-06-24
PT86450A (en) 1988-01-01
PH25913A (en) 1991-12-19
PT86450B (pt) 1990-11-20
DK673787D0 (da) 1987-12-21
NO875381D0 (no) 1987-12-22
FI875603A (fi) 1988-06-24
AU616875B2 (en) 1991-11-14

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