NO875355L - Rensing av rekombinant beta-interferon innbefattende rp-hplc. - Google Patents

Rensing av rekombinant beta-interferon innbefattende rp-hplc.

Info

Publication number
NO875355L
NO875355L NO875355A NO875355A NO875355L NO 875355 L NO875355 L NO 875355L NO 875355 A NO875355 A NO 875355A NO 875355 A NO875355 A NO 875355A NO 875355 L NO875355 L NO 875355L
Authority
NO
Norway
Prior art keywords
hplc
purification
beta interferon
recombinant beta
interferon including
Prior art date
Application number
NO875355A
Other languages
English (en)
Other versions
NO875355D0 (no
Inventor
Susan Hershenson
E Ev Shaked
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of NO875355D0 publication Critical patent/NO875355D0/no
Publication of NO875355L publication Critical patent/NO875355L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO875355A 1986-12-23 1987-12-21 Rensing av rekombinant beta-interferon innbefattende rp-hplc. NO875355L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/946,083 US4894330A (en) 1986-12-23 1986-12-23 Purification of recombinant beta-interferon incorporating RP-HPLC

Publications (2)

Publication Number Publication Date
NO875355D0 NO875355D0 (no) 1987-12-21
NO875355L true NO875355L (no) 1988-06-24

Family

ID=25483933

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875355A NO875355L (no) 1986-12-23 1987-12-21 Rensing av rekombinant beta-interferon innbefattende rp-hplc.

Country Status (8)

Country Link
US (1) US4894330A (no)
EP (1) EP0274900A3 (no)
JP (1) JPS63169995A (no)
AU (1) AU617656B2 (no)
CA (1) CA1295087C (no)
DK (1) DK685587A (no)
IE (1) IE873498L (no)
NO (1) NO875355L (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1222427B (it) * 1987-07-31 1990-09-05 Sclavo Spa Procedimento per la purificazione di interferone
US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it
ES2097806T3 (es) * 1990-03-30 1997-04-16 Shiseido Co Ltd Procedimiento para purificar un polipeptido.
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
KR950701934A (ko) * 1993-04-30 1995-05-17 아사이 잇뻬이 소수성 폴리펩티드의 정제방법(purification method for hydrophobic polypeptide)
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
US7544354B2 (en) * 2000-10-27 2009-06-09 Novartis Vaccines And Diagnostics Methods of protein purification and recovery
JP4129178B2 (ja) * 2000-11-07 2008-08-06 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 安定化されたインターフェロン組成物
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
ZA200700168B (en) 2001-10-10 2010-02-24 Novo Nordisk As Remodeling and glycoconjugation of peptides
EP2292271A3 (en) 2001-10-10 2011-09-14 BioGeneriX AG Remodelling and glycoconjugation of an antibody
GEP20084487B (en) * 2002-12-26 2008-09-25 Mountain View Pharmaceuticals Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof
NZ541124A (en) * 2002-12-26 2008-08-29 Mountain View Pharmaceuticals Polymer conjugates of interferon-beta with enhanced biological potency
SG155777A1 (en) 2003-04-09 2009-10-29 Neose Technologies Inc Glycopegylation methods and proteins/peptides produced by the methods
KR20070007086A (ko) 2004-02-02 2007-01-12 암브룩스, 인코포레이티드 변형된 인간의 4 개의 나선형 다발 폴리펩티드 및 이의용도
US20090214472A1 (en) * 2004-03-01 2009-08-27 Enzon Pharmaceuticals Inc. Interferon-beta polymer conjugates
US20070179113A1 (en) * 2005-05-19 2007-08-02 Schering Aktiengesellachaft GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
EP1885858A2 (en) * 2005-05-19 2008-02-13 Bayer Schering Pharma Aktiengesellschaft Treatment of disease using an improved regulated expression system
US20080076729A1 (en) * 2005-05-19 2008-03-27 Schering Aktiengesellachaft Interferon-beta gene therapy using an improved, regulated expression system
GT200600210A (es) * 2005-05-19 2007-01-03 Schering Ag Terapia genica de interferon-beta usdando un sistema mejorado de expresion regulada
NZ580686A (en) * 2007-05-02 2012-11-30 Ambrx Inc Modified interferon beta polypeptides and their uses
EP2207890A4 (en) * 2007-10-05 2010-12-15 Barofold Inc HIGH PRESSURE PROCESSING OF AGGREGATED INTERFERONS
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (no) * 1978-11-24 1982-12-04 Hoffmann La Roche
US4289689A (en) * 1980-03-14 1981-09-15 Hoffmann-La Roche Inc. Preparation of homogeneous human fibroblast interferon
ZA803943B (en) * 1979-07-31 1981-06-24 Hoffmann La Roche Homogeneous fibroblast interferon and method for manufacture thereof
DE2943016C2 (de) * 1979-10-24 1984-09-06 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Verfahren zur Reinigung von Interferon
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
US4485017A (en) * 1982-12-22 1984-11-27 Cetus Corporation Isolation of human interferon by immunosorbent and high performance liquid chromatography
IL67896A (en) * 1983-02-13 1987-03-31 Yeda Res & Dev Two biologically active human gama interferon subtypes,purification thereof and pharmaceutical compositions containing them
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
DD235077A1 (de) * 1985-03-04 1986-04-23 Akad Wissenschaften Ddr Verfahren zur gewinnung von hochreinem interleukin-2
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts

Also Published As

Publication number Publication date
JPS63169995A (ja) 1988-07-13
AU8292287A (en) 1988-06-23
EP0274900A2 (en) 1988-07-20
US4894330A (en) 1990-01-16
CA1295087C (en) 1992-01-28
IE873498L (en) 1988-06-23
DK685587D0 (da) 1987-12-23
EP0274900A3 (en) 1989-08-23
AU617656B2 (en) 1991-12-05
DK685587A (da) 1988-06-24
NO875355D0 (no) 1987-12-21

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