NO873131L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme 8-(lavere alkyl)-bicyclo-(4.2.0)-octanderivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk virksomme 8-(lavere alkyl)-bicyclo-(4.2.0)-octanderivater.Info
- Publication number
- NO873131L NO873131L NO873131A NO873131A NO873131L NO 873131 L NO873131 L NO 873131L NO 873131 A NO873131 A NO 873131A NO 873131 A NO873131 A NO 873131A NO 873131 L NO873131 L NO 873131L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- chem
- octander
- bicyclo
- derivatives
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
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- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
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- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
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- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
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- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/891,509 US4678805A (en) | 1985-03-27 | 1986-07-28 | Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties |
Publications (4)
Publication Number | Publication Date |
---|---|
NO873131D0 NO873131D0 (no) | 1987-07-27 |
NO873131L true NO873131L (no) | 1988-01-29 |
NO166442B NO166442B (no) | 1991-04-15 |
NO166442C NO166442C (no) | 1991-07-24 |
Family
ID=25398316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO873131A NO166442C (no) | 1986-07-28 | 1987-07-27 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme 8-(lavere alkyl)-bicyclo-(4.2.0)-octanderivater. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4678805A (no) |
EP (1) | EP0255098B1 (no) |
JP (1) | JPS6345232A (no) |
KR (1) | KR880001561A (no) |
AT (1) | ATE63899T1 (no) |
AU (1) | AU605493B2 (no) |
DE (1) | DE3770360D1 (no) |
DK (1) | DK391087A (no) |
FI (1) | FI873271A (no) |
GR (1) | GR3002024T3 (no) |
HU (1) | HU197870B (no) |
IL (1) | IL83339A0 (no) |
NO (1) | NO166442C (no) |
NZ (1) | NZ221197A (no) |
PH (1) | PH24200A (no) |
ZA (1) | ZA875513B (no) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5049497A (en) * | 1986-08-25 | 1991-09-17 | Syntex (U.S.A.) Inc. | Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives |
US4735966A (en) * | 1986-08-25 | 1988-04-05 | Syntex (U.S.A.) Inc. | Novel substituted (4.2.0)bicyclooctane derivatives with valuable therapeutic properties |
US4730078A (en) * | 1987-05-13 | 1988-03-08 | G. D. Searle & Co. | Allenic prostacyclins |
US4983627A (en) * | 1988-11-10 | 1991-01-08 | Syntex (U.S.A.) Inc. | Novel 6-alkyl and 6.8-dialkylbicyclo(4.2.0)octane derivatives |
EP0610797B1 (en) * | 1993-02-10 | 1998-05-06 | Kabushiki Kaisha Yutaka Giken | Floating type brake disk assembly |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
US4306076A (en) * | 1980-04-23 | 1981-12-15 | The Upjohn Company | Inter-phenylene CBA compounds |
US4608388A (en) * | 1985-03-27 | 1986-08-26 | Syntex (U.S.A.) Inc. | Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties |
US4735966A (en) * | 1986-08-25 | 1988-04-05 | Syntex (U.S.A.) Inc. | Novel substituted (4.2.0)bicyclooctane derivatives with valuable therapeutic properties |
-
1986
- 1986-07-28 US US06/891,509 patent/US4678805A/en not_active Expired - Fee Related
-
1987
- 1987-07-27 AU AU76125/87A patent/AU605493B2/en not_active Expired - Fee Related
- 1987-07-27 ZA ZA875513A patent/ZA875513B/xx unknown
- 1987-07-27 EP EP87110873A patent/EP0255098B1/en not_active Expired - Lifetime
- 1987-07-27 IL IL83339A patent/IL83339A0/xx unknown
- 1987-07-27 HU HU873418A patent/HU197870B/hu not_active IP Right Cessation
- 1987-07-27 JP JP62189963A patent/JPS6345232A/ja active Pending
- 1987-07-27 PH PH35587A patent/PH24200A/en unknown
- 1987-07-27 DE DE8787110873T patent/DE3770360D1/de not_active Expired - Fee Related
- 1987-07-27 NO NO873131A patent/NO166442C/no unknown
- 1987-07-27 NZ NZ221197A patent/NZ221197A/en unknown
- 1987-07-27 KR KR1019870008179A patent/KR880001561A/ko not_active Application Discontinuation
- 1987-07-27 DK DK391087A patent/DK391087A/da not_active Application Discontinuation
- 1987-07-27 FI FI873271A patent/FI873271A/fi not_active Application Discontinuation
- 1987-07-27 AT AT87110873T patent/ATE63899T1/de active
-
1991
- 1991-05-30 GR GR90401109T patent/GR3002024T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO873131D0 (no) | 1987-07-27 |
EP0255098B1 (en) | 1991-05-29 |
ZA875513B (en) | 1989-03-29 |
EP0255098A1 (en) | 1988-02-03 |
JPS6345232A (ja) | 1988-02-26 |
IL83339A0 (en) | 1987-12-31 |
NZ221197A (en) | 1990-01-29 |
HUT44471A (en) | 1988-03-28 |
HU197870B (en) | 1989-06-28 |
US4678805A (en) | 1987-07-07 |
KR880001561A (ko) | 1988-04-25 |
FI873271A0 (fi) | 1987-07-27 |
NO166442C (no) | 1991-07-24 |
AU605493B2 (en) | 1991-01-17 |
DE3770360D1 (de) | 1991-07-04 |
AU7612587A (en) | 1988-02-11 |
FI873271A (fi) | 1988-01-29 |
DK391087A (da) | 1988-01-29 |
DK391087D0 (da) | 1987-07-27 |
GR3002024T3 (en) | 1992-12-30 |
PH24200A (en) | 1990-04-10 |
ATE63899T1 (de) | 1991-06-15 |
NO166442B (no) | 1991-04-15 |
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