NO872674D0 - Metastasehemmende middel. - Google Patents

Metastasehemmende middel.

Info

Publication number
NO872674D0
NO872674D0 NO872674A NO872674A NO872674D0 NO 872674 D0 NO872674 D0 NO 872674D0 NO 872674 A NO872674 A NO 872674A NO 872674 A NO872674 A NO 872674A NO 872674 D0 NO872674 D0 NO 872674D0
Authority
NO
Norway
Prior art keywords
metastase
inhibitor
metastase inhibitor
Prior art date
Application number
NO872674A
Other languages
English (en)
Other versions
NO872674L (no
Inventor
Irun Cohen
Israel Vlodavsky
Amiram Eldor
Yaakov Naparstek
Original Assignee
Hadassah Med Org
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadassah Med Org, Yeda Res & Dev filed Critical Hadassah Med Org
Publication of NO872674D0 publication Critical patent/NO872674D0/no
Publication of NO872674L publication Critical patent/NO872674L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO872674A 1986-06-26 1987-06-25 Metastasehemmende middel. NO872674L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL79255A IL79255A0 (en) 1986-06-26 1986-06-26 Composition for metastasis prevention

Publications (2)

Publication Number Publication Date
NO872674D0 true NO872674D0 (no) 1987-06-25
NO872674L NO872674L (no) 1987-12-28

Family

ID=11056897

Family Applications (1)

Application Number Title Priority Date Filing Date
NO872674A NO872674L (no) 1986-06-26 1987-06-25 Metastasehemmende middel.

Country Status (7)

Country Link
US (1) US4882318A (no)
EP (1) EP0254067A3 (no)
JP (1) JPS6388128A (no)
AU (1) AU7470587A (no)
DK (1) DK331387A (no)
IL (1) IL79255A0 (no)
NO (1) NO872674L (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262403A (en) * 1986-03-10 1993-11-16 Board Of Regents, The University Of Texas System Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II
US5206223A (en) * 1986-06-26 1993-04-27 Yeda Research And Development Co. Ltd. Method for inhibiting heparanase activity
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
IL86753A0 (en) * 1988-06-15 1988-11-30 Hadassah Med Org Pharmaceutical compositions for treatment of lupus
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
US5340932A (en) * 1989-08-18 1994-08-23 Ajorca S.A. Substances with heparin-like structure and their method of production
KR927003090A (ko) * 1989-08-23 1992-12-17 하다사 메디칼 오르가니제이션 헤파린효소를 포함하는 상처 치유 약제
DK148890D0 (da) * 1990-06-19 1990-06-19 Novo Nordisk As Farmaceutisk praeparat
ATE148713T1 (de) * 1990-07-24 1997-02-15 Seikagaku Kogyo Co Ltd Glykosaminoglykan gemischt mit phospholipid oder lipid, seine herstellung und krebszellenmetastaseninhibitor
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
US6060296A (en) * 1991-07-03 2000-05-09 The Salk Institute For Biological Studies Protein kinases
US6750207B1 (en) * 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
CN1111910A (zh) * 1993-07-06 1995-11-15 霍夫曼-拉罗奇有限公司 乳腺调节素，非激素依赖性乳腺癌细胞特异蛋白
FR2708198B1 (fr) * 1993-07-28 1995-10-20 Dior Christian Parfums Composition cosmétique ou pharmaceutique, notamment dermatologique contenant un extrait de Tephrosia, en particulier Tephrosia purpurea.
AU4808997A (en) 1996-09-30 1998-04-24 Brigham And Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
US20020088019A1 (en) * 1997-09-02 2002-07-04 Oron Yacoby-Zeevi Methods of and pharmaceutical compositions for improving implantation of embryos
US6699672B1 (en) * 1997-09-02 2004-03-02 Insight Biopharmaceuticals Ltd. Heparanase specific molecular probes and their use research and medical applications
US20010006630A1 (en) * 1997-09-02 2001-07-05 Oron Yacoby-Zeevi Introducing a biological material into a patient
US20030161823A1 (en) * 1998-08-31 2003-08-28 Neta Ilan Therapeutic and cosmetic uses of heparanases
US6177545B1 (en) * 1997-09-02 2001-01-23 Insight Strategy & Marketing Ltd. Heparanase specific molecular probes and their use in research and medical applications
US6190875B1 (en) * 1997-09-02 2001-02-20 Insight Strategy & Marketing Ltd. Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe
US20040213789A1 (en) * 1997-09-02 2004-10-28 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies
JP2002504376A (ja) 1998-02-24 2002-02-12 ファルマシア・アンド・アップジョン・カンパニー ヒト血小板ヘパラナーゼポリペプチド、それをコードするポリヌクレオチド分子、およびヘパラナーゼ活性を改変する化合物の同定方法
US20030217375A1 (en) * 1998-08-31 2003-11-20 Eyal Zcharia Transgenic animals expressing heparanase and uses thereof
EP1157118A4 (en) * 1999-03-01 2002-07-17 Insight Strategy & Marketing POLYNUCLEOTID ENCODING A POLYPEPTIDE WITH HEPARANASE ACTIVITY AND ITS EXPRESSION IN GENETICALLY MODIFIED CELLS
CA2393855A1 (en) 1999-12-22 2001-06-28 Oxford Glycosciences (Uk) Ltd. Homologues of human heparanase and splice variants thereof
US7781416B2 (en) 2000-01-25 2010-08-24 Sigma-Tau Research Switzerland S.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
WO2001081569A2 (en) * 2000-04-20 2001-11-01 Pharmacia & Upjohn Company Heparanase ii, a human heparanase paralog
CN1197587C (zh) * 2000-06-09 2005-04-20 中国科学院上海细胞生物学研究所 N－位脱硫酸肝素在预防和治疗炎症中的应用
MXPA04002217A (es) * 2001-09-12 2004-07-08 Sigma Tau Ind Farmaceuti Derivados de glucosaminoglucanas parcialmente desulfatados como inhibidores de heparanasa, dotados con actividad antiangiogenica y libres de efectos anticoagulantes.
US6671189B2 (en) * 2001-11-09 2003-12-30 Minebea Co., Ltd. Power converter having primary and secondary side switches
US7285536B2 (en) * 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
US20060269552A1 (en) * 2003-06-09 2006-11-30 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monclonal antibody and other anti-heparanase antibodies
WO2005076743A2 (en) * 2004-02-17 2005-08-25 Yeda Research And Development Co. Ltd. Disaccharide molecules and derivatives thereof and methods of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR81305E (fr) * 1959-01-29 1963-09-06 Roussel Uclaf Procédé de préparation de la nu-désulfo héparine et de ses dérivés acyles
CA1226816A (en) * 1982-12-20 1987-09-15 Moses J. Folkman Inhibition of angiogenesis
GR79775B (no) * 1983-03-22 1984-10-31 Cegedur

Also Published As

Publication number Publication date
DK331387A (da) 1987-12-27
US4882318A (en) 1989-11-21
NO872674L (no) 1987-12-28
EP0254067A2 (en) 1988-01-27
JPS6388128A (ja) 1988-04-19
AU7470587A (en) 1988-01-07
IL79255A0 (en) 1986-09-30
EP0254067A3 (en) 1988-09-14
DK331387D0 (da) 1987-06-26

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