IL79255A0 - Composition for metastasis prevention - Google Patents

Composition for metastasis prevention

Info

Publication number
IL79255A0
IL79255A0 IL79255A IL7925586A IL79255A0 IL 79255 A0 IL79255 A0 IL 79255A0 IL 79255 A IL79255 A IL 79255A IL 7925586 A IL7925586 A IL 7925586A IL 79255 A0 IL79255 A0 IL 79255A0
Authority
IL
Israel
Prior art keywords
composition
metastasis prevention
metastasis
prevention
Prior art date
Application number
IL79255A
Other languages
English (en)
Original Assignee
Hadassah Med Org
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadassah Med Org, Yeda Res & Dev filed Critical Hadassah Med Org
Priority to IL79255A priority Critical patent/IL79255A0/xx
Publication of IL79255A0 publication Critical patent/IL79255A0/xx
Priority to US07/067,582 priority patent/US4882318A/en
Priority to NO872674A priority patent/NO872674L/no
Priority to EP87109142A priority patent/EP0254067A3/en
Priority to AU74705/87A priority patent/AU7470587A/en
Priority to JP62159515A priority patent/JPS6388128A/ja
Priority to DK331387A priority patent/DK331387A/da
Priority to CA000540717A priority patent/CA1318591C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL79255A 1986-06-26 1986-06-26 Composition for metastasis prevention IL79255A0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IL79255A IL79255A0 (en) 1986-06-26 1986-06-26 Composition for metastasis prevention
US07/067,582 US4882318A (en) 1986-06-26 1987-06-24 Method for decreasing tumor metastasis
NO872674A NO872674L (no) 1986-06-26 1987-06-25 Metastasehemmende middel.
EP87109142A EP0254067A3 (en) 1986-06-26 1987-06-25 Composition for metastasis prevention
AU74705/87A AU7470587A (en) 1986-06-26 1987-06-25 A method for decreasing tumor metastasis using a heparin composition
JP62159515A JPS6388128A (ja) 1986-06-26 1987-06-26 腫瘍細胞転移抑制剤
DK331387A DK331387A (da) 1986-06-26 1987-06-26 Praeparat til forhindring af metastase
CA000540717A CA1318591C (en) 1986-06-26 1987-06-26 Composition containing heparin or derivative thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL79255A IL79255A0 (en) 1986-06-26 1986-06-26 Composition for metastasis prevention

Publications (1)

Publication Number Publication Date
IL79255A0 true IL79255A0 (en) 1986-09-30

Family

ID=11056897

Family Applications (1)

Application Number Title Priority Date Filing Date
IL79255A IL79255A0 (en) 1986-06-26 1986-06-26 Composition for metastasis prevention

Country Status (7)

Country Link
US (1) US4882318A (xx)
EP (1) EP0254067A3 (xx)
JP (1) JPS6388128A (xx)
AU (1) AU7470587A (xx)
DK (1) DK331387A (xx)
IL (1) IL79255A0 (xx)
NO (1) NO872674L (xx)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262403A (en) * 1986-03-10 1993-11-16 Board Of Regents, The University Of Texas System Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II
US5206223A (en) * 1986-06-26 1993-04-27 Yeda Research And Development Co. Ltd. Method for inhibiting heparanase activity
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
IL86753A0 (en) * 1988-06-15 1988-11-30 Hadassah Med Org Pharmaceutical compositions for treatment of lupus
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
US5340932A (en) * 1989-08-18 1994-08-23 Ajorca S.A. Substances with heparin-like structure and their method of production
JP3188691B2 (ja) * 1989-08-23 2001-07-16 ハダサ メディカル オーガナイゼーション ヘパラナーゼを含む創傷治癒用組成物
DK148890D0 (da) * 1990-06-19 1990-06-19 Novo Nordisk As Farmaceutisk praeparat
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
US5464942A (en) * 1990-07-24 1995-11-07 Seikagaku Kogyo Kabushiki Kaisha Phospholipid- or lipid-linked glycosaminoglycan and process for producing the same
US6060296A (en) * 1991-07-03 2000-05-09 The Salk Institute For Biological Studies Protein kinases
US6750207B1 (en) * 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
RU95116901A (ru) * 1993-07-06 1997-03-27 Ф.Хоффманн-Ля Рош Аг (Ch) Маммамодулин-гормононезависимый специфичный протеин опухолевых клеток молочной железы
FR2708198B1 (fr) * 1993-07-28 1995-10-20 Dior Christian Parfums Composition cosmétique ou pharmaceutique, notamment dermatologique contenant un extrait de Tephrosia, en particulier Tephrosia purpurea.
WO1998014169A1 (en) 1996-09-30 1998-04-09 Brigham & Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
US20040213789A1 (en) * 1997-09-02 2004-10-28 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies
US6699672B1 (en) * 1997-09-02 2004-03-02 Insight Biopharmaceuticals Ltd. Heparanase specific molecular probes and their use research and medical applications
US20020088019A1 (en) * 1997-09-02 2002-07-04 Oron Yacoby-Zeevi Methods of and pharmaceutical compositions for improving implantation of embryos
US6177545B1 (en) * 1997-09-02 2001-01-23 Insight Strategy & Marketing Ltd. Heparanase specific molecular probes and their use in research and medical applications
US20030161823A1 (en) * 1998-08-31 2003-08-28 Neta Ilan Therapeutic and cosmetic uses of heparanases
US6190875B1 (en) * 1997-09-02 2001-02-20 Insight Strategy & Marketing Ltd. Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe
US20010006630A1 (en) * 1997-09-02 2001-07-05 Oron Yacoby-Zeevi Introducing a biological material into a patient
AU2759199A (en) 1998-02-24 1999-09-15 Pharmacia & Upjohn Company Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity
US20030217375A1 (en) * 1998-08-31 2003-11-20 Eyal Zcharia Transgenic animals expressing heparanase and uses thereof
AU2878600A (en) * 1999-03-01 2000-09-21 Hadasit Medical Research Services & Development Company Ltd Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
EP1240313B1 (en) 1999-12-22 2006-07-26 Ucb, S.A. Homologue enzymes of human heparanase and splice variants thereof
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
US7781416B2 (en) 2000-01-25 2010-08-24 Sigma-Tau Research Switzerland S.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
EP1276862A2 (en) * 2000-04-20 2003-01-22 Pharmacia & Upjohn Company Heparanase ii, a human heparanase paralog
CN1197587C (zh) * 2000-06-09 2005-04-20 中国科学院上海细胞生物学研究所 N－位脱硫酸肝素在预防和治疗炎症中的应用
ES2431362T3 (es) * 2001-09-12 2013-11-26 Sigma-Tau Research Switzerland S.A. Derivados de glicosaminoglicanos totalmente N-desulfatados como agentes inhibidores de la heparanasa, dotados con actividad antiangiogénica y desprovistos de efecto anticoagulante
US6671189B2 (en) * 2001-11-09 2003-12-30 Minebea Co., Ltd. Power converter having primary and secondary side switches
US7285536B2 (en) * 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
WO2004108065A2 (en) * 2003-06-09 2004-12-16 Insight Biopharmaceuticals Ltd. Heparanase activity neutralizing anti- heparanase monoclonal antibody and other anti-heparanase antibodies
US20080274998A1 (en) * 2004-02-17 2008-11-06 Yeda Research And Development Co. Ltd. Disaccharide Molecules and Derivatives Thereof and Methods of Using Same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR81305E (fr) * 1959-01-29 1963-09-06 Roussel Uclaf Procédé de préparation de la nu-désulfo héparine et de ses dérivés acyles
CA1226816A (en) * 1982-12-20 1987-09-15 Moses J. Folkman Inhibition of angiogenesis
GR79775B (xx) * 1983-03-22 1984-10-31 Cegedur

Also Published As

Publication number Publication date
NO872674D0 (no) 1987-06-25
DK331387A (da) 1987-12-27
EP0254067A3 (en) 1988-09-14
AU7470587A (en) 1988-01-07
US4882318A (en) 1989-11-21
NO872674L (no) 1987-12-28
JPS6388128A (ja) 1988-04-19
DK331387D0 (da) 1987-06-26
EP0254067A2 (en) 1988-01-27

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