NO820623L - Imidazodiazepiner - Google Patents

Imidazodiazepiner

Info

Publication number
NO820623L
NO820623L NO820623A NO820623A NO820623L NO 820623 L NO820623 L NO 820623L NO 820623 A NO820623 A NO 820623A NO 820623 A NO820623 A NO 820623A NO 820623 L NO820623 L NO 820623L
Authority
NO
Norway
Prior art keywords
hydrogen
imidazodiazepines
benzodiazepines
trifluoromethyl
cyano
Prior art date
Application number
NO820623A
Other languages
English (en)
Other versions
NO157377C (no
NO157377B (no
Inventor
Walter Hunkeler
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO820623L publication Critical patent/NO820623L/no
Publication of NO157377B publication Critical patent/NO157377B/no
Publication of NO157377C publication Critical patent/NO157377C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO820623A 1981-02-27 1982-02-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive imidazodiazepiner. NO157377C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH134081 1981-02-27

Publications (3)

Publication Number Publication Date
NO820623L true NO820623L (no) 1982-08-30
NO157377B NO157377B (no) 1987-11-30
NO157377C NO157377C (no) 1988-03-05

Family

ID=4208189

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820623A NO157377C (no) 1981-02-27 1982-02-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive imidazodiazepiner.

Country Status (27)

Country Link
US (1) US4352817A (no)
EP (1) EP0059389B1 (no)
JP (1) JPS57156488A (no)
KR (1) KR830009104A (no)
AT (1) ATE10745T1 (no)
AU (1) AU551811B2 (no)
BR (1) BR8200949A (no)
CA (1) CA1184176A (no)
DE (1) DE3261496D1 (no)
DK (1) DK87182A (no)
ES (3) ES509924A0 (no)
FI (1) FI73431C (no)
GB (1) GB2093842B (no)
GR (1) GR76032B (no)
HU (1) HU185089B (no)
IE (1) IE52696B1 (no)
IL (1) IL65072A (no)
MC (1) MC1441A1 (no)
NO (1) NO157377C (no)
NZ (1) NZ199796A (no)
OA (1) OA07010A (no)
PH (1) PH18255A (no)
PT (1) PT74505B (no)
YU (1) YU25282A (no)
ZA (1) ZA821129B (no)
ZM (1) ZM482A1 (no)
ZW (1) ZW3082A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC1528A1 (fr) * 1982-07-21 1984-04-13 Hoffmann La Roche Imidazobenzodiazepines
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
FI850191L (fi) * 1984-01-19 1985-07-20 Hoffmann La Roche Imidazodiazepinderivat.
DE3689096T2 (de) * 1985-07-09 1994-01-27 Nippon Petrochemicals Co Ltd Feuerhemmende Polyolefinzusammensetzung.
ES2015052B3 (es) * 1986-03-03 1990-08-01 Ube Industries Maquina de troquelado vertical.
ZA881538B (en) * 1987-03-10 1988-09-12 F. Hoffmann-La Roche & Co. Aktiengesellschaft Imidazodiazepine derivatives
CA1327008C (en) * 1988-01-15 1994-02-15 Walter Merz Anti-psychotic imidazobenzodiazepine
ES2052837T3 (es) * 1988-08-05 1994-07-16 Hoffmann La Roche Derivados marcados radioactivamente de la benzodiazepina.
US5096695A (en) * 1988-08-05 1992-03-17 Hoffmann-Laroche Inc. Radioiodine benzodiazepines as brain imaging agents
CA1327572C (en) * 1988-08-31 1994-03-08 F. Hoffmann-La Roche Ag Imidazodiazepine derivatives
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US5109013A (en) * 1990-06-06 1992-04-28 A. H. Robins Company, Incorporated 2-(2-substituted aminoethyl)-1,4-dialkyl-3,4-dihydro-1H-1,3,5]triazepino[3,2-a]benzimidazol-5(2H)-ones as muscle relaxants
US5438035A (en) * 1994-06-24 1995-08-01 American Cyanamid Company Methods for controlling undesirable plant species with benzodiazepine compounds
JO2259B1 (en) * 1999-05-12 2004-10-07 اف. هوفمان- لاروش أيه جي‏ Method for the manufacture of diazapine derivatives
EP1888594A2 (en) * 2005-05-16 2008-02-20 Wisys Technology Foundation, Inc. Gabaergic agents to treat memory deficits
CA2696703C (en) 2007-08-20 2016-07-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
CN113087713B (zh) * 2021-03-29 2022-10-04 中国人民解放军军事科学院军事医学研究院 一类苯并二氮䓬衍生物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509371B2 (en) * 1975-08-07 1980-05-08 F. Hoffmann-La Roche Ag Diazepine Derivatives
GB1600600A (en) * 1977-03-10 1981-10-21 Diamond Shamrock Chem Plasticiser compositions for use with synthetic resin polymers
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives

Also Published As

Publication number Publication date
ES8304982A1 (es) 1983-04-01
AU8066682A (en) 1982-09-02
ES8405008A1 (es) 1984-06-01
AU551811B2 (en) 1986-05-15
DE3261496D1 (en) 1985-01-24
GR76032B (no) 1984-08-03
HU185089B (en) 1984-11-28
ZW3082A1 (en) 1982-09-29
ES518262A0 (es) 1984-06-01
ZM482A1 (en) 1982-11-22
EP0059389A1 (de) 1982-09-08
PT74505A (en) 1982-03-01
ES518263A0 (es) 1984-06-01
OA07010A (fr) 1983-08-31
JPS57156488A (en) 1982-09-27
PH18255A (en) 1985-05-13
IL65072A0 (en) 1982-04-30
NO157377C (no) 1988-03-05
GB2093842A (en) 1982-09-08
CA1184176A (en) 1985-03-19
FI73431C (fi) 1987-10-09
ATE10745T1 (de) 1984-12-15
FI820199L (fi) 1982-08-28
IE820420L (en) 1982-08-27
GB2093842B (en) 1984-10-17
IE52696B1 (en) 1988-01-20
EP0059389B1 (de) 1984-12-12
DK87182A (da) 1982-08-28
KR830009104A (ko) 1983-12-17
ZA821129B (en) 1983-01-26
NZ199796A (en) 1985-10-11
IL65072A (en) 1985-12-31
PT74505B (en) 1984-11-26
US4352817A (en) 1982-10-05
FI73431B (fi) 1987-06-30
ES8405009A1 (es) 1984-06-01
YU25282A (en) 1989-08-31
BR8200949A (pt) 1983-01-04
MC1441A1 (fr) 1982-12-06
NO157377B (no) 1987-11-30
ES509924A0 (es) 1983-04-01

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