NO801469L - Pyrimidinforbindelser og fremgangsmaate til deres fremstilling - Google Patents
Pyrimidinforbindelser og fremgangsmaate til deres fremstillingInfo
- Publication number
- NO801469L NO801469L NO801469A NO801469A NO801469L NO 801469 L NO801469 L NO 801469L NO 801469 A NO801469 A NO 801469A NO 801469 A NO801469 A NO 801469A NO 801469 L NO801469 L NO 801469L
- Authority
- NO
- Norway
- Prior art keywords
- pyrimid
- procedures
- compounds
- preparation
- pyrimid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH466979 | 1979-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO801469L true NO801469L (no) | 1980-11-19 |
Family
ID=4280399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO801469A NO801469L (no) | 1979-05-18 | 1980-05-16 | Pyrimidinforbindelser og fremgangsmaate til deres fremstilling |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0019811A1 (fr) |
JP (1) | JPS55154971A (fr) |
KR (1) | KR830002757A (fr) |
AR (1) | AR228256A1 (fr) |
AU (1) | AU5848480A (fr) |
DD (1) | DD150609A5 (fr) |
DK (1) | DK214480A (fr) |
ES (1) | ES491514A0 (fr) |
FI (1) | FI801600A (fr) |
GB (1) | GB2052487B (fr) |
GR (1) | GR68453B (fr) |
IE (1) | IE49803B1 (fr) |
IL (1) | IL60086A (fr) |
MA (1) | MA18829A1 (fr) |
NO (1) | NO801469L (fr) |
NZ (1) | NZ193730A (fr) |
OA (1) | OA06533A (fr) |
PL (1) | PL224313A1 (fr) |
PT (1) | PT71251A (fr) |
ZA (1) | ZA802909B (fr) |
ZW (1) | ZW11880A1 (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4507146A (en) * | 1982-12-28 | 1985-03-26 | Ciba-Geigy Corporation | 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity |
DE3829469A1 (de) * | 1988-08-31 | 1990-03-01 | Bayer Ag | Verfahren zur herstellung von substituierten n-azinyl-n'-sulfonyl-isothioharnstoffen und n-azinyl-iminodithiokohlensaeure-s,s-diester als zwischenprodukte zu ihrer herstellung |
EP0954316A4 (fr) * | 1997-09-03 | 2002-02-13 | Lilly Co Eli | Derives de pyrimidine |
CA2422371C (fr) | 2000-09-15 | 2010-05-18 | Vertex Pharmaceuticals Incorporated | Composes de pyrazole utiles comme inhibiteurs de proteine kinase |
US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
US7473691B2 (en) | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
US20030105090A1 (en) | 2000-12-21 | 2003-06-05 | David Bebbington | Pyrazole compounds useful as protein kinase inhibitors |
CZ20032341A3 (cs) * | 2001-01-31 | 2004-12-15 | Synaptic Pharmaceutical Corporation | Použití antagonistů GAL3 receptoru pro léčbu deprese a/nebo úzkosti |
KR20040099324A (ko) | 2002-03-13 | 2004-11-26 | 유로-셀티큐 에스.에이. | 아릴 치환된 피리미딘 및 이것의 용도 |
US20040009981A1 (en) | 2002-03-15 | 2004-01-15 | David Bebbington | Compositions useful as inhibitors of protein kinases |
WO2003077656A1 (fr) * | 2002-03-15 | 2003-09-25 | Ciba Specialty Chemicals Holding Inc. | 4-aminopyrimidines et leur utilisation pour le traitement antimicrobien de surfaces |
MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
CN101037438A (zh) | 2002-08-02 | 2007-09-19 | 沃泰克斯药物股份有限公司 | 用作gsk-3的抑制剂的吡唑组合物 |
US7601718B2 (en) | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
ATE542814T1 (de) | 2005-08-18 | 2012-02-15 | Vertex Pharma | Pyrazinkinaseinhibitoren |
BRPI0619708A2 (pt) | 2005-11-03 | 2011-10-11 | Vertex Pharma | composto, composição, método para inibir a atividade da proteìna aurora quinase numa amostra biológica, método para tratar distúrbio proliferativo e método para tratar cáncer |
AU2007317435A1 (en) | 2006-11-02 | 2008-05-15 | Vertex Pharmaceuticals Incorporated | Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases |
NZ577768A (en) | 2006-12-19 | 2012-01-12 | Vertex Pharma | Aminopyrimidines useful as inhibitors of protein kinases |
ES2435997T3 (es) | 2007-03-09 | 2013-12-26 | Vertex Pharmaceuticals, Inc. | Aminopirimidinas útiles como inhibidores de las proteínas cinasas |
JP5393489B2 (ja) | 2007-03-09 | 2014-01-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | 蛋白キナーゼの阻害剤として有用なアミノピリミジン |
JP2010520887A (ja) | 2007-03-09 | 2010-06-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | 蛋白キナーゼの阻害剤として有用なアミノピリジン |
JP2010523700A (ja) | 2007-04-13 | 2010-07-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼインヒビターとして有用なアミノピリミジン |
MX2009011810A (es) | 2007-05-02 | 2010-01-14 | Vertex Pharma | Tiazoles y pirazoles utiles como inhibidores de cinasa. |
WO2008137621A1 (fr) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines servant d'inhibiteurs de kinases |
AR067762A1 (es) | 2007-07-31 | 2009-10-21 | Vertex Pharma | Proceso para preparar 5-fluoro-1h-pirazolo (3,4-b) piridin-3-amina y derivados de la misma |
WO2010027921A1 (fr) | 2008-09-03 | 2010-03-11 | Vertex Pharmaceuticals Incorporated | Co-cristaux et formulations pharmaceutiques les comprenant |
EP2364314B1 (fr) * | 2008-12-09 | 2014-03-12 | Gilead Sciences, Inc. | Modulateurs de récepteurs de type toll (tlr) |
KR102328682B1 (ko) * | 2018-08-27 | 2021-11-18 | 주식회사 대웅제약 | 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE754832A (fr) * | 1969-08-14 | 1971-02-15 | Beecham Group Ltd | Iminazolines |
-
1980
- 1980-05-05 MA MA19025A patent/MA18829A1/fr unknown
- 1980-05-13 DD DD80221082A patent/DD150609A5/de unknown
- 1980-05-14 ES ES491514A patent/ES491514A0/es active Granted
- 1980-05-15 NZ NZ193730A patent/NZ193730A/xx unknown
- 1980-05-15 IL IL60086A patent/IL60086A/xx unknown
- 1980-05-16 NO NO801469A patent/NO801469L/no unknown
- 1980-05-16 FI FI801600A patent/FI801600A/fi not_active Application Discontinuation
- 1980-05-16 IE IE1023/80A patent/IE49803B1/en unknown
- 1980-05-16 PT PT71251A patent/PT71251A/pt unknown
- 1980-05-16 ZA ZA00802909A patent/ZA802909B/xx unknown
- 1980-05-16 GB GB8016309A patent/GB2052487B/en not_active Expired
- 1980-05-16 DK DK214480A patent/DK214480A/da not_active Application Discontinuation
- 1980-05-16 ZW ZW118/80A patent/ZW11880A1/xx unknown
- 1980-05-16 EP EP80102724A patent/EP0019811A1/fr not_active Withdrawn
- 1980-05-16 AU AU58484/80A patent/AU5848480A/en not_active Abandoned
- 1980-05-16 GR GR61963A patent/GR68453B/el unknown
- 1980-05-17 OA OA57113A patent/OA06533A/fr unknown
- 1980-05-17 KR KR1019800001944A patent/KR830002757A/ko unknown
- 1980-05-17 JP JP6586380A patent/JPS55154971A/ja active Pending
- 1980-05-17 PL PL22431380A patent/PL224313A1/xx unknown
- 1980-05-19 AR AR281109A patent/AR228256A1/es active
Also Published As
Publication number | Publication date |
---|---|
AU5848480A (en) | 1980-11-20 |
KR830002757A (ko) | 1983-05-30 |
AR228256A1 (es) | 1983-02-15 |
PL224313A1 (fr) | 1981-02-13 |
ZA802909B (en) | 1981-05-27 |
ZW11880A1 (en) | 1980-12-17 |
JPS55154971A (en) | 1980-12-02 |
PT71251A (en) | 1980-06-01 |
GB2052487A (en) | 1981-01-28 |
DD150609A5 (de) | 1981-09-09 |
GR68453B (fr) | 1981-12-30 |
FI801600A (fi) | 1980-11-19 |
DK214480A (da) | 1980-11-19 |
ES8104279A1 (es) | 1981-04-16 |
IE801023L (en) | 1980-11-18 |
NZ193730A (en) | 1982-12-21 |
EP0019811A1 (fr) | 1980-12-10 |
IE49803B1 (en) | 1985-12-25 |
OA06533A (fr) | 1981-07-31 |
IL60086A0 (en) | 1980-07-31 |
GB2052487B (en) | 1983-05-11 |
MA18829A1 (fr) | 1980-12-31 |
IL60086A (en) | 1984-03-30 |
ES491514A0 (es) | 1981-04-16 |
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