NO771243L - Fremgangsm}te ved fremstilling av trans-octahydro-pyrido-indolo-benzazepiner. - Google Patents
Fremgangsm}te ved fremstilling av trans-octahydro-pyrido-indolo-benzazepiner.Info
- Publication number
- NO771243L NO771243L NO771243A NO771243A NO771243L NO 771243 L NO771243 L NO 771243L NO 771243 A NO771243 A NO 771243A NO 771243 A NO771243 A NO 771243A NO 771243 L NO771243 L NO 771243L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- formula
- compounds
- trans
- indolo
- Prior art date
Links
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- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 125000005188 oxoalkyl group Chemical group 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229940113116 polyethylene glycol 1000 Drugs 0.000 description 1
- 229940057838 polyethylene glycol 4000 Drugs 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 150000003138 primary alcohols Chemical class 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 150000003333 secondary alcohols Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229960005333 tetrabenazine Drugs 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- WHRNULOCNSKMGB-UHFFFAOYSA-N tetrahydrofuran thf Chemical compound C1CCOC1.C1CCOC1 WHRNULOCNSKMGB-UHFFFAOYSA-N 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/675,113 US4070467A (en) | 1976-04-08 | 1976-04-08 | Trans-octahydro-pyrido-indolo-benzazepine-3-alkanols, -alkanonitriles,-alkanoic acid and ester as tranquilizers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO771243L true NO771243L (no) | 1977-10-11 |
Family
ID=24709117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO771243A NO771243L (no) | 1976-04-08 | 1977-04-06 | Fremgangsm}te ved fremstilling av trans-octahydro-pyrido-indolo-benzazepiner. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4070467A (nl) |
| JP (1) | JPS52125200A (nl) |
| AU (1) | AU507702B2 (nl) |
| BE (1) | BE853423A (nl) |
| DD (1) | DD132662A5 (nl) |
| DE (1) | DE2715354A1 (nl) |
| DK (1) | DK154977A (nl) |
| ES (1) | ES457653A1 (nl) |
| FI (1) | FI771089A (nl) |
| FR (1) | FR2347366A1 (nl) |
| GB (1) | GB1573646A (nl) |
| GR (1) | GR63657B (nl) |
| IL (1) | IL51841A (nl) |
| LU (1) | LU77087A1 (nl) |
| NL (1) | NL7703899A (nl) |
| NO (1) | NO771243L (nl) |
| NZ (1) | NZ183825A (nl) |
| PH (1) | PH12613A (nl) |
| PT (1) | PT66408B (nl) |
| SE (1) | SE7702302L (nl) |
| ZA (1) | ZA772165B (nl) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3983123A (en) * | 1973-01-22 | 1976-09-28 | Endo Laboratories, Inc. | Trans-octahydropyridoindolobenzazepines |
| US3932650A (en) * | 1973-01-22 | 1976-01-13 | E. I. Du Pont De Nemours & Company | Trans-octahydropyridoindolobenzazepines as central nervous system depressants |
-
1976
- 1976-04-08 US US05/675,113 patent/US4070467A/en not_active Expired - Lifetime
-
1977
- 1977-03-02 SE SE7702302A patent/SE7702302L/xx not_active Application Discontinuation
- 1977-04-05 AU AU23988/77A patent/AU507702B2/en not_active Expired
- 1977-04-06 ES ES457653A patent/ES457653A1/es not_active Expired
- 1977-04-06 FI FI771089A patent/FI771089A/fi not_active Application Discontinuation
- 1977-04-06 GR GR53181A patent/GR63657B/el unknown
- 1977-04-06 DE DE19772715354 patent/DE2715354A1/de active Pending
- 1977-04-06 NO NO771243A patent/NO771243L/no unknown
- 1977-04-06 PT PT66408A patent/PT66408B/pt unknown
- 1977-04-06 DK DK154977A patent/DK154977A/da not_active IP Right Cessation
- 1977-04-06 PH PH19636A patent/PH12613A/en unknown
- 1977-04-07 NZ NZ183825A patent/NZ183825A/xx unknown
- 1977-04-07 NL NL7703899A patent/NL7703899A/nl not_active Application Discontinuation
- 1977-04-07 IL IL51841A patent/IL51841A/xx unknown
- 1977-04-07 DD DD7700198298A patent/DD132662A5/xx unknown
- 1977-04-07 FR FR7710597A patent/FR2347366A1/fr active Pending
- 1977-04-08 JP JP3962577A patent/JPS52125200A/ja active Pending
- 1977-04-08 LU LU77087A patent/LU77087A1/xx unknown
- 1977-04-08 BE BE176569A patent/BE853423A/xx unknown
- 1977-04-12 GB GB15070/77A patent/GB1573646A/en not_active Expired
- 1977-05-07 ZA ZA00772165A patent/ZA772165B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI771089A (nl) | 1977-10-09 |
| US4070467A (en) | 1978-01-24 |
| LU77087A1 (nl) | 1977-12-01 |
| DD132662A5 (de) | 1978-10-18 |
| DK154977A (da) | 1977-10-09 |
| ES457653A1 (es) | 1978-07-16 |
| FR2347366A1 (fr) | 1977-11-04 |
| GR63657B (en) | 1979-11-28 |
| IL51841A (en) | 1979-11-30 |
| BE853423A (fr) | 1977-10-10 |
| AU507702B2 (en) | 1980-02-21 |
| PT66408A (en) | 1977-05-01 |
| GB1573646A (en) | 1980-08-28 |
| DE2715354A1 (de) | 1977-10-27 |
| JPS52125200A (en) | 1977-10-20 |
| NL7703899A (nl) | 1977-10-11 |
| ZA772165B (en) | 1978-05-30 |
| PH12613A (en) | 1979-07-05 |
| SE7702302L (sv) | 1977-10-19 |
| IL51841A0 (en) | 1977-06-30 |
| AU2398877A (en) | 1978-10-12 |
| PT66408B (en) | 1978-09-13 |
| NZ183825A (en) | 1980-03-05 |
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