NO750246L - - Google Patents
Info
- Publication number
- NO750246L NO750246L NO750246A NO750246A NO750246L NO 750246 L NO750246 L NO 750246L NO 750246 A NO750246 A NO 750246A NO 750246 A NO750246 A NO 750246A NO 750246 L NO750246 L NO 750246L
- Authority
- NO
- Norway
- Prior art keywords
- solution
- weight
- friedelan
- ethanol
- patient
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 46
- 238000011282 treatment Methods 0.000 claims description 30
- 238000002360 preparation method Methods 0.000 claims description 25
- OFMXGFHWLZPCFL-ACRUQRPVSA-N Friedelan-3-one Natural products C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3CCC(=O)[C@H]1C OFMXGFHWLZPCFL-ACRUQRPVSA-N 0.000 claims description 24
- JUUHNUPNMCGYDT-UHFFFAOYSA-N Friedelin Natural products CC1CC2C(C)(CCC3(C)C4CC(C)(C)CCC4(C)CCC23C)C5CCC(=O)C(C)C15 JUUHNUPNMCGYDT-UHFFFAOYSA-N 0.000 claims description 24
- OFMXGFHWLZPCFL-UHFFFAOYSA-N Triedelin Natural products CC12CCC3(C)C4CC(C)(C)CCC4(C)CCC3(C)C2CCC2(C)C1CCC(=O)C2C OFMXGFHWLZPCFL-UHFFFAOYSA-N 0.000 claims description 24
- OFMXGFHWLZPCFL-SVRPQWSVSA-N friedelin Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3CCC(=O)[C@@H]1C OFMXGFHWLZPCFL-SVRPQWSVSA-N 0.000 claims description 24
- 206010028980 Neoplasm Diseases 0.000 claims description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 201000011510 cancer Diseases 0.000 claims description 17
- 229930002875 chlorophyll Natural products 0.000 claims description 16
- 235000019804 chlorophyll Nutrition 0.000 claims description 16
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 14
- 239000005011 phenolic resin Substances 0.000 claims description 14
- 229920001568 phenolic resin Polymers 0.000 claims description 14
- KXGFMDJXCMQABM-UHFFFAOYSA-N 2-methoxy-6-methylphenol Chemical compound [CH]OC1=CC=CC([CH])=C1O KXGFMDJXCMQABM-UHFFFAOYSA-N 0.000 claims description 13
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 13
- 230000005907 cancer growth Effects 0.000 claims description 8
- 230000002401 inhibitory effect Effects 0.000 claims description 8
- 238000007865 diluting Methods 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 2
- 229920005989 resin Polymers 0.000 claims description 2
- 239000011347 resin Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- KVSNMTUIMXZPLU-UHFFFAOYSA-N D:A-friedo-oleanane Natural products CC12CCC3(C)C4CC(C)(C)CCC4(C)CCC3(C)C2CCC2(C)C1CCCC2C KVSNMTUIMXZPLU-UHFFFAOYSA-N 0.000 claims 1
- YFKBKEUBAZXAGG-UHFFFAOYSA-N friedelan Natural products CC1C(=O)CCC2(C)C3CCC4(C)C5CC(C)(C)CCC5(C)CCC4(C)C3CCC12C YFKBKEUBAZXAGG-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 description 8
- 235000012054 meals Nutrition 0.000 description 6
- 230000004596 appetite loss Effects 0.000 description 5
- 208000019017 loss of appetite Diseases 0.000 description 5
- 235000021266 loss of appetite Nutrition 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 210000003932 urinary bladder Anatomy 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 208000032839 leukemia Diseases 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000004584 weight gain Effects 0.000 description 2
- 235000019786 weight gain Nutrition 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 208000006593 Urologic Neoplasms Diseases 0.000 description 1
- 238000002441 X-ray diffraction Methods 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000021152 breakfast Nutrition 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 206010021654 increased appetite Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 235000019645 odor Nutrition 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX15306174 | 1974-08-08 | ||
US52141074A | 1974-11-06 | 1974-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO750246L true NO750246L (nl) | 1976-02-10 |
Family
ID=26641075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO750246A NO750246L (nl) | 1974-08-08 | 1975-01-28 |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5126210A (nl) |
CA (1) | CA1026672A (nl) |
DE (1) | DE2508338C2 (nl) |
DO (1) | DOP1975002269A (nl) |
FR (1) | FR2281103A1 (nl) |
GB (1) | GB1475651A (nl) |
IL (1) | IL46517A (nl) |
IN (1) | IN142315B (nl) |
IT (1) | IT1056277B (nl) |
LU (1) | LU71933A1 (nl) |
NL (1) | NL184665C (nl) |
NO (1) | NO750246L (nl) |
PH (1) | PH12112A (nl) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT100939A (pt) * | 1992-10-08 | 1994-05-31 | Ineti Inst Nac Engenh E Tecnol | Novos triterpenoides e seco-triterpenoides com aplicacao como agentes bioactivos |
-
1975
- 1975-01-28 IL IL46517A patent/IL46517A/xx unknown
- 1975-01-28 NO NO750246A patent/NO750246L/no unknown
- 1975-01-28 GB GB369075A patent/GB1475651A/en not_active Expired
- 1975-02-06 PH PH16778A patent/PH12112A/en unknown
- 1975-02-14 CA CA220,209A patent/CA1026672A/en not_active Expired
- 1975-02-26 FR FR7505927A patent/FR2281103A1/fr active Granted
- 1975-02-26 DE DE2508338A patent/DE2508338C2/de not_active Expired
- 1975-02-27 LU LU71933A patent/LU71933A1/xx unknown
- 1975-03-05 IN IN428/CAL/1975A patent/IN142315B/en unknown
- 1975-03-06 JP JP50026595A patent/JPS5126210A/ja active Pending
- 1975-03-20 NL NLAANVRAGE7503371,A patent/NL184665C/nl not_active IP Right Cessation
- 1975-03-28 IT IT09377/75A patent/IT1056277B/it active
- 1975-05-24 DO DO1975002269A patent/DOP1975002269A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CA1026672A (en) | 1978-02-21 |
IL46517A0 (en) | 1975-05-22 |
IL46517A (en) | 1978-10-31 |
JPS5126210A (nl) | 1976-03-04 |
FR2281103B1 (nl) | 1980-02-15 |
PH12112A (en) | 1978-11-02 |
DE2508338A1 (de) | 1976-02-19 |
DOP1975002269A (es) | 1989-07-07 |
GB1475651A (en) | 1977-06-01 |
NL184665C (nl) | 1989-10-02 |
FR2281103A1 (fr) | 1976-03-05 |
NL7503371A (nl) | 1976-02-10 |
IT1056277B (it) | 1982-01-30 |
DE2508338C2 (de) | 1985-08-14 |
LU71933A1 (nl) | 1977-01-06 |
IN142315B (nl) | 1977-06-25 |
AU7829775A (en) | 1976-08-19 |
NL184665B (nl) | 1989-05-01 |
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