NO741889L - Fremgangsmåte for fremstilling av <alfa>-aryl-propionsyrer - Google Patents

Fremgangsmåte for fremstilling av <alfa>-aryl-propionsyrer

Info

Publication number
NO741889L
NO741889L NO741889A NO741889A NO741889L NO 741889 L NO741889 L NO 741889L NO 741889 A NO741889 A NO 741889A NO 741889 A NO741889 A NO 741889A NO 741889 L NO741889 L NO 741889L
Authority
NO
Norway
Prior art keywords
aryl
alpha
preparation
propionic acids
propionic
Prior art date
Application number
NO741889A
Other languages
English (en)
Other versions
NO142258B (no
NO142258C (no
Inventor
Bernard John Armitage
James Edward Jefferey
James Gordon Tantum
John Stuart Nicholson
Original Assignee
The Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Co Plc filed Critical The Boots Co Plc
Publication of NO741889L publication Critical patent/NO741889L/no
Publication of NO142258B publication Critical patent/NO142258B/no
Publication of NO142258C publication Critical patent/NO142258C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/373Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
NO741889A 1973-05-24 1974-05-22 Fremgangsmaate for fremstilling av alfa-aryl-propionsyrer NO142258C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2484473A GB1459084A (en) 1973-05-24 1973-05-24 Preparation of arylalkanoic acid

Publications (3)

Publication Number Publication Date
NO741889L true NO741889L (no) 1974-11-26
NO142258B NO142258B (no) 1980-04-14
NO142258C NO142258C (no) 1980-07-30

Family

ID=10218145

Family Applications (1)

Application Number Title Priority Date Filing Date
NO741889A NO142258C (no) 1973-05-24 1974-05-22 Fremgangsmaate for fremstilling av alfa-aryl-propionsyrer

Country Status (19)

Country Link
US (1) US3959364A (no)
JP (1) JPS5652890B2 (no)
AT (1) AT341504B (no)
CA (1) CA1004226A (no)
CH (1) CH589592A5 (no)
CS (1) CS185226B2 (no)
CY (1) CY919A (no)
DD (1) DD111897A5 (no)
DK (1) DK153138C (no)
ES (1) ES426574A1 (no)
FI (1) FI58908C (no)
GB (1) GB1459084A (no)
HU (1) HU168736B (no)
IN (1) IN139756B (no)
NL (1) NL189459C (no)
NO (1) NO142258C (no)
RO (1) RO63965A (no)
SE (1) SE408550B (no)
YU (1) YU143374A (no)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS175831B1 (no) * 1974-12-17 1977-05-31
US4151302A (en) * 1975-06-28 1979-04-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Araliphatic dihalogen compounds composition and method of use
JPS5262237A (en) * 1975-11-19 1977-05-23 Ono Pharmaceut Co Ltd Process for preparation of alpha-substituted phenylalkane carboxylic a cid
HU183210B (en) * 1977-02-16 1984-04-28 Syntex Pharma Int Process for preparing complexes of 2-aryl-propionic acids
US4144397A (en) * 1977-02-16 1979-03-13 Syntex Corporation Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex
DE3022599A1 (de) * 1979-06-18 1981-01-08 Glaxo Group Ltd Alkansaeurederivate
US4278516A (en) * 1979-06-28 1981-07-14 Ethyl Corporation Method for the preparation of 2-fluoro-4-monobromomethylbiphenyl
US4371473A (en) * 1979-06-28 1983-02-01 Ethyl Corporation Preparation of 2-(2-fluoro-4-biphenylyl)propionic acid and corresponding nitride
US4324904A (en) * 1979-12-19 1982-04-13 The Upjohn Company Processes for the preparation of hydratropic acids and esters
US4518799A (en) * 1979-12-19 1985-05-21 The Upjohn Company Processes for the preparation of hydratropic acids
JPS6350715Y2 (no) * 1980-04-28 1988-12-27
JPS56161693U (no) * 1980-04-30 1981-12-01
US4422979A (en) * 1980-09-22 1983-12-27 Ethyl Corporation Fluoro-substituted biphenylyl compounds and processes
JPS57203035A (en) * 1981-06-05 1982-12-13 Taisho Pharmaceut Co Ltd Carboxylic acid ester
US4370278A (en) * 1981-11-02 1983-01-25 Ethyl Corporation Nucleophilic substitution process
US4502995A (en) * 1981-11-02 1985-03-05 Ethyl Corporation Nucleophilic substitution process
IT1211135B (it) * 1981-11-24 1989-09-29 Ausonia Farma Srl Composti ad attivita'analgesica e antiinfiammatoria, processo per la loro preparazione e relative composizioni farmaceutiche.
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
JPS59105795U (ja) * 1983-01-06 1984-07-16 三洋電機株式会社 マイクロストリツプ線路
US4540795A (en) * 1983-02-25 1985-09-10 Ethyl Corporation Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophilic substitution processes for preparing them
WO1987000519A1 (en) * 1985-07-12 1987-01-29 The Upjohn Company Chemical compounds comrpising substituted phenylrings
US4992350A (en) * 1988-09-30 1991-02-12 Ricoh Company, Ltd. Biphenyl compounds and electrophotographic photoconductor comprising the same
CA2005845C (en) * 1988-12-21 2001-01-09 Isoo Shimizu Method for preparing a-(4-isobutylphenyl) propionic acid or its precursor
DE69210323T3 (de) * 1991-07-31 1999-06-02 Tessenderlo Chemie N.V., Bruxelles Verfahren zur Alpha-Monoalkierung von Arylacetonitrilen, Arylacetoestern und Arylessigsäuren
US5691376A (en) * 1994-02-17 1997-11-25 American Home Products Corporation Substituted biphenyl derivatives
AU692839B2 (en) * 1994-02-17 1998-06-18 American Home Products Corporation Substituted biphenyl derivatives as phosphodiesterase inhibitors
US5792886A (en) * 1997-01-08 1998-08-11 Albemarle Corporation Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof
US6080888A (en) * 1997-01-08 2000-06-27 Albemarle Corporation Preparation of olefinic compounds and carboxylic derivatives thereof
US6096920A (en) * 1997-01-08 2000-08-01 Albemarle Corporation Preparation of carboxylic compounds and their derivatives
KR100448641B1 (ko) * 1997-08-01 2004-11-16 주식회사 코오롱 2-(4-할로메틸페닐)프로피온산의 제조 방법
US5874614A (en) * 1997-12-11 1999-02-23 Albemarle Corporation Sodium (S)-2-(6-methoxy-2-naphthyl)propionate monohydrate
US5859292A (en) * 1997-12-11 1999-01-12 Albemarle Corporation Preparation of high purity sodium (S)-2(6-methoxy-2-naphthyl)propionate
KR100529157B1 (ko) * 1999-01-28 2005-11-17 주식회사 코오롱 방향족 프로피온산의 제조방법
JP2006335639A (ja) * 2003-01-23 2006-12-14 Nagase & Co Ltd 光学活性なフルルビプロフェンの製造方法
EP1484304A1 (en) 2003-05-28 2004-12-08 Dainippon Ink And Chemicals, Inc. Process for the preparation of fluorophenylalkylene acid derivatives
CA2677125C (en) * 2007-02-01 2018-07-10 Myriad Genetics, Inc. Drug substance preparations, pharmaceutical compositions and dosage forms
JP5183153B2 (ja) * 2007-11-01 2013-04-17 花王株式会社 クロスカップリング化合物の製造方法
BRPI1007861A2 (pt) 2009-02-25 2016-11-29 Council Scient Ind Res processo para preparação ecológica de 3,5-dibromo 4- hidroxibenzonitrila
JP6504530B2 (ja) 2015-09-30 2019-04-24 大正製薬株式会社 光学活性な2−(2−フルオロビフェニル−4−イル)プロパン酸の製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2290401A (en) * 1941-07-23 1942-07-21 Univ Ohio State Res Found Method of preparing polycyclic aromatic carboxylic acids
US2921939A (en) * 1955-11-28 1960-01-19 Metal & Thermit Corp Process for preparing alpha-substituted acetic acids
US3385887A (en) * 1961-02-02 1968-05-28 Boots Pure Drug Co Ltd 4-isobutylphenylacetic acid
DE2145650A1 (de) * 1971-09-13 1973-03-22 Merck Patent Gmbh Fluoren-derivate

Also Published As

Publication number Publication date
NO142258B (no) 1980-04-14
FI58908C (fi) 1981-05-11
US3959364A (en) 1976-05-25
IN139756B (no) 1976-07-24
JPS5652890B2 (no) 1981-12-15
FI160174A (no) 1974-11-25
CA1004226A (en) 1977-01-25
CS185226B2 (en) 1978-09-15
HU168736B (no) 1976-07-28
SE408550B (sv) 1979-06-18
AT341504B (de) 1978-02-10
NL7406897A (no) 1974-11-26
ATA425974A (de) 1977-06-15
DK153138C (da) 1988-10-31
DK278974A (no) 1975-01-13
DD111897A5 (no) 1975-03-12
GB1459084A (en) 1976-12-22
YU143374A (en) 1982-02-28
CY919A (en) 1977-12-23
NL189459B (nl) 1992-11-16
JPS5040541A (no) 1975-04-14
DK153138B (da) 1988-06-20
RO63965A (fr) 1978-09-15
NO142258C (no) 1980-07-30
NL189459C (nl) 1993-04-16
CH589592A5 (no) 1977-07-15
ES426574A1 (es) 1976-07-01
FI58908B (fi) 1981-01-30

Similar Documents

Publication Publication Date Title
NO741889L (no) Fremgangsmåte for fremstilling av &lt;alfa&gt;-aryl-propionsyrer
AR203626A1 (es) Sintesis de nuevos acidos heterociclico-indol-3-ii-acetic
BE809578A (fr) Procede de preparation de 1 alpha
SE423631B (sv) Forfarande for framstellning av oxaalhyl-dialkylxantiner
IT1048188B (it) Procedimento per la produzione di o metilbenzanilide
SE7808959L (sv) Forfarande for framstellning av dylenoxid
SE7710599L (sv) Forfarande for framstellning av bensisoxazoler
SE404199B (sv) Forfarande for framstellning av vattenhaltiga metallbearbetningsvetskor innehallande amidokarbonsyror
SE7908625L (sv) Acetylglykosylmykofenolsyraforeningar for framstellning av glykosylmykofenolsyraforeningar
AR207429A1 (es) Procedimiento de preparacion de acidos 7-acilamido-3-cefem-4-carboxilicos
SE424994B (sv) Forfarande for framstellning av nya pseudotrisackarider
SE416731B (sv) Forfarande for framstellning av nya penicilliner
SE411212B (sv) Forfarande for framstellning av 3-halogen-cefalosporiner
NO142628C (no) Fremgangsmaate for fremstilling av polylaktoner
NO146596C (no) Fremgangsmaate for fremstilling av 6-deoksytetracykliner
NO790627L (no) Fremgangsmaate for fremstilling av hydroksyalkylxantiner
SE417601B (sv) Forfarande for framstellning av amidinokarbamider
SE418085B (sv) Forfarande for framstellning av nya sulfamoylbensoesyraamider
NO843825L (no) Fremgangsmaate for fremstilling av 6-deoksytetracyklin
RO70082A (ro) Procedeu pentru prepararea ureei
SE418176B (sv) Forfarande for framstellning av substituerade indanettiksyror
RO69264A (ro) Procedeu pentru prepararea alfa-amino-alcoolilor
SE409994B (sv) Forfarande for framstellning av amidinokarbamider
SE411211B (sv) Forfarande for framstellning av 3-halogencefalosporiner
SE401506B (sv) Forfarande for framstellning av bifenylyletrar