NO335515B1 - In vitro fremgangsmåte for fremstilling av en populasjon av celler som omfatter hematopoetiske stamceller, cellepopulasjon, anvendelse derav og farmasøytisk preparat omfattende nevnte cellepopulasjon. - Google Patents

In vitro fremgangsmåte for fremstilling av en populasjon av celler som omfatter hematopoetiske stamceller, cellepopulasjon, anvendelse derav og farmasøytisk preparat omfattende nevnte cellepopulasjon. Download PDF

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Publication number
NO335515B1
NO335515B1 NO20062709A NO20062709A NO335515B1 NO 335515 B1 NO335515 B1 NO 335515B1 NO 20062709 A NO20062709 A NO 20062709A NO 20062709 A NO20062709 A NO 20062709A NO 335515 B1 NO335515 B1 NO 335515B1
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cells
cxcr4
stem cells
cell population
cell
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NO20062709A
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Norwegian (no)
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NO20062709L (no
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Tsvee Lapidot
Joy Kahn
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Yeda Res & Dev
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Publication of NO20062709L publication Critical patent/NO20062709L/no
Publication of NO335515B1 publication Critical patent/NO335515B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/21Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Genetics & Genomics (AREA)
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  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
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  • Hematology (AREA)
  • Cell Biology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
NO20062709A 2003-11-13 2006-06-12 In vitro fremgangsmåte for fremstilling av en populasjon av celler som omfatter hematopoetiske stamceller, cellepopulasjon, anvendelse derav og farmasøytisk preparat omfattende nevnte cellepopulasjon. NO335515B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15886803A IL158868A0 (en) 2003-11-13 2003-11-13 Methods of generating and using stem cells enriched with immature primitive progenitor
PCT/IL2004/001018 WO2005047494A2 (en) 2003-11-13 2004-11-08 Haematopoietic stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
NO20062709L NO20062709L (no) 2006-08-11
NO335515B1 true NO335515B1 (no) 2014-12-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062709A NO335515B1 (no) 2003-11-13 2006-06-12 In vitro fremgangsmåte for fremstilling av en populasjon av celler som omfatter hematopoetiske stamceller, cellepopulasjon, anvendelse derav og farmasøytisk preparat omfattende nevnte cellepopulasjon.

Country Status (9)

Country Link
US (2) US20080025957A1 (enExample)
EP (1) EP1682653B1 (enExample)
JP (2) JP2007511219A (enExample)
AU (1) AU2004288879B2 (enExample)
CA (1) CA2545409A1 (enExample)
ES (1) ES2534724T3 (enExample)
IL (2) IL158868A0 (enExample)
NO (1) NO335515B1 (enExample)
WO (1) WO2005047494A2 (enExample)

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EP2679221B1 (en) 2006-10-20 2020-09-23 Children's Medical Center Corporation Method to enhance tissue regeneration
WO2008073748A1 (en) 2006-12-08 2008-06-19 University Of Rochester Expansion of hematopoietic stem cells
CA2682469A1 (en) 2007-03-30 2008-10-09 The Cleveland Clinic Foundation Method of treating ischemic disorders
US8198083B1 (en) 2007-10-31 2012-06-12 William Gunter Loudon Organotypic slices of the central nervous system
WO2009079451A2 (en) 2007-12-14 2009-06-25 The Cleveland Clinic Foundation Compositions and methods of promoting wound healing
EP3031907B1 (en) 2008-11-06 2021-01-06 Indiana University Research and Technology Corporation Materials and methods to enhance hematopoietic stem cells engraftment procedures
US20120283315A1 (en) 2009-08-28 2012-11-08 Penn Marc S Sdf-1 delivery for treating ischemic tissue
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
MX359398B (es) 2011-09-30 2018-09-27 Bluebird Bio Inc Compuestos para transduccion viral mejorada.
WO2013082243A1 (en) * 2011-12-02 2013-06-06 Fate Therapeutics, Inc. Enhanced stem cell composition
EP3297694A1 (en) 2015-05-21 2018-03-28 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
EP3413896B1 (en) 2016-02-12 2021-03-17 Bluebird Bio, Inc. Vcn enhancer compositions and methods of using the same
CA3014078A1 (en) 2016-02-12 2017-08-17 Bluebird Bio, Inc. Vcn enhancer compositions and methods of using the same
GB201807944D0 (en) * 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Compositions and methods for haematopoietic stem cell transplantation
WO2022054999A1 (ko) * 2020-09-14 2022-03-17 주식회사 제너로스 생착능이 증가된 줄기세포의 제조 방법
WO2023010068A2 (en) * 2021-07-28 2023-02-02 Cartesian Therapeutics, Inc. Multiprotein-engineered cells secreting a multispecific antibody

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US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
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Also Published As

Publication number Publication date
IL158868A0 (en) 2004-05-12
AU2004288879B2 (en) 2011-06-16
IL175430A0 (en) 2006-09-05
WO2005047494A2 (en) 2005-05-26
AU2004288879A1 (en) 2005-05-26
ES2534724T3 (es) 2015-04-27
CA2545409A1 (en) 2005-05-26
EP1682653B1 (en) 2015-03-25
US8367057B2 (en) 2013-02-05
JP2012125249A (ja) 2012-07-05
US20080025957A1 (en) 2008-01-31
JP2007511219A (ja) 2007-05-10
NO20062709L (no) 2006-08-11
US20110268712A1 (en) 2011-11-03
EP1682653A2 (en) 2006-07-26
IL175430A (en) 2015-01-29
WO2005047494A3 (en) 2005-06-23
JP5547221B2 (ja) 2014-07-09

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