IL158868A0 - Methods of generating and using stem cells enriched with immature primitive progenitor - Google Patents

Methods of generating and using stem cells enriched with immature primitive progenitor

Info

Publication number
IL158868A0
IL158868A0 IL15886803A IL15886803A IL158868A0 IL 158868 A0 IL158868 A0 IL 158868A0 IL 15886803 A IL15886803 A IL 15886803A IL 15886803 A IL15886803 A IL 15886803A IL 158868 A0 IL158868 A0 IL 158868A0
Authority
IL
Israel
Prior art keywords
generating
methods
stem cells
cells enriched
primitive progenitor
Prior art date
Application number
IL15886803A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL15886803A priority Critical patent/IL158868A0/xx
Publication of IL158868A0 publication Critical patent/IL158868A0/xx
Priority to AU2004288879A priority patent/AU2004288879B2/en
Priority to US10/578,291 priority patent/US20080025957A1/en
Priority to ES04799327.4T priority patent/ES2534724T3/es
Priority to JP2006539071A priority patent/JP2007511219A/ja
Priority to PCT/IL2004/001018 priority patent/WO2005047494A2/en
Priority to EP04799327.4A priority patent/EP1682653B1/en
Priority to CA002545409A priority patent/CA2545409A1/en
Priority to IL175430A priority patent/IL175430A/en
Priority to NO20062709A priority patent/NO335515B1/no
Priority to US13/031,466 priority patent/US8367057B2/en
Priority to JP2012032163A priority patent/JP5547221B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
IL15886803A 2003-11-13 2003-11-13 Methods of generating and using stem cells enriched with immature primitive progenitor IL158868A0 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IL15886803A IL158868A0 (en) 2003-11-13 2003-11-13 Methods of generating and using stem cells enriched with immature primitive progenitor
CA002545409A CA2545409A1 (en) 2003-11-13 2004-11-08 Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them
JP2006539071A JP2007511219A (ja) 2003-11-13 2004-11-08 移植に好適な幹細胞、その調製およびそれらを含む医薬組成物
US10/578,291 US20080025957A1 (en) 2003-11-13 2004-11-08 Stem Cells Suitable for Transplantation, their Preparation and Pharmaceutical Compositions Comprising Them
ES04799327.4T ES2534724T3 (es) 2003-11-13 2004-11-08 Células madre hematopoyéticas adecuadas para el trasplante, su preparación y composiciones farmacéuticas que las comprenden
AU2004288879A AU2004288879B2 (en) 2003-11-13 2004-11-08 Haematopoietic stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them
PCT/IL2004/001018 WO2005047494A2 (en) 2003-11-13 2004-11-08 Haematopoietic stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them
EP04799327.4A EP1682653B1 (en) 2003-11-13 2004-11-08 Haematopoietic stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them
IL175430A IL175430A (en) 2003-11-13 2006-05-04 A method for the preparation, use and use of stem cell ulceration
NO20062709A NO335515B1 (no) 2003-11-13 2006-06-12 In vitro fremgangsmåte for fremstilling av en populasjon av celler som omfatter hematopoetiske stamceller, cellepopulasjon, anvendelse derav og farmasøytisk preparat omfattende nevnte cellepopulasjon.
US13/031,466 US8367057B2 (en) 2003-11-13 2011-02-21 Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them
JP2012032163A JP5547221B2 (ja) 2003-11-13 2012-02-16 移植に好適な幹細胞、その調製およびそれらを含む医薬組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15886803A IL158868A0 (en) 2003-11-13 2003-11-13 Methods of generating and using stem cells enriched with immature primitive progenitor

Publications (1)

Publication Number Publication Date
IL158868A0 true IL158868A0 (en) 2004-05-12

Family

ID=34044273

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15886803A IL158868A0 (en) 2003-11-13 2003-11-13 Methods of generating and using stem cells enriched with immature primitive progenitor
IL175430A IL175430A (en) 2003-11-13 2006-05-04 A method for the preparation, use and use of stem cell ulceration

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL175430A IL175430A (en) 2003-11-13 2006-05-04 A method for the preparation, use and use of stem cell ulceration

Country Status (9)

Country Link
US (2) US20080025957A1 (enExample)
EP (1) EP1682653B1 (enExample)
JP (2) JP2007511219A (enExample)
AU (1) AU2004288879B2 (enExample)
CA (1) CA2545409A1 (enExample)
ES (1) ES2534724T3 (enExample)
IL (2) IL158868A0 (enExample)
NO (1) NO335515B1 (enExample)
WO (1) WO2005047494A2 (enExample)

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US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
CN101495623B (zh) 2006-03-24 2013-09-11 儿童医疗中心有限公司 调节造血干细胞生长的方法
EP2679221B1 (en) 2006-10-20 2020-09-23 Children's Medical Center Corporation Method to enhance tissue regeneration
WO2008073748A1 (en) 2006-12-08 2008-06-19 University Of Rochester Expansion of hematopoietic stem cells
CA2682469A1 (en) 2007-03-30 2008-10-09 The Cleveland Clinic Foundation Method of treating ischemic disorders
US8198083B1 (en) 2007-10-31 2012-06-12 William Gunter Loudon Organotypic slices of the central nervous system
WO2009079451A2 (en) 2007-12-14 2009-06-25 The Cleveland Clinic Foundation Compositions and methods of promoting wound healing
EP3031907B1 (en) 2008-11-06 2021-01-06 Indiana University Research and Technology Corporation Materials and methods to enhance hematopoietic stem cells engraftment procedures
US20120283315A1 (en) 2009-08-28 2012-11-08 Penn Marc S Sdf-1 delivery for treating ischemic tissue
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
MX359398B (es) 2011-09-30 2018-09-27 Bluebird Bio Inc Compuestos para transduccion viral mejorada.
WO2013082243A1 (en) * 2011-12-02 2013-06-06 Fate Therapeutics, Inc. Enhanced stem cell composition
EP3297694A1 (en) 2015-05-21 2018-03-28 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
EP3413896B1 (en) 2016-02-12 2021-03-17 Bluebird Bio, Inc. Vcn enhancer compositions and methods of using the same
CA3014078A1 (en) 2016-02-12 2017-08-17 Bluebird Bio, Inc. Vcn enhancer compositions and methods of using the same
GB201807944D0 (en) * 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Compositions and methods for haematopoietic stem cell transplantation
WO2022054999A1 (ko) * 2020-09-14 2022-03-17 주식회사 제너로스 생착능이 증가된 줄기세포의 제조 방법
WO2023010068A2 (en) * 2021-07-28 2023-02-02 Cartesian Therapeutics, Inc. Multiprotein-engineered cells secreting a multispecific antibody

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US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
JP2874751B2 (ja) 1986-04-09 1999-03-24 ジェンザイム・コーポレーション 希望する蛋白質をミルク中へ分泌する遺伝子移植動物
US4879111A (en) * 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US4873316A (en) * 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US4965195A (en) * 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
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US6326198B1 (en) * 1990-06-14 2001-12-04 Regents Of The University Of Michigan Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
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Also Published As

Publication number Publication date
AU2004288879B2 (en) 2011-06-16
IL175430A0 (en) 2006-09-05
WO2005047494A2 (en) 2005-05-26
AU2004288879A1 (en) 2005-05-26
ES2534724T3 (es) 2015-04-27
CA2545409A1 (en) 2005-05-26
EP1682653B1 (en) 2015-03-25
US8367057B2 (en) 2013-02-05
JP2012125249A (ja) 2012-07-05
US20080025957A1 (en) 2008-01-31
JP2007511219A (ja) 2007-05-10
NO335515B1 (no) 2014-12-22
NO20062709L (no) 2006-08-11
US20110268712A1 (en) 2011-11-03
EP1682653A2 (en) 2006-07-26
IL175430A (en) 2015-01-29
WO2005047494A3 (en) 2005-06-23
JP5547221B2 (ja) 2014-07-09

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