CA2545409A1 - Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them - Google Patents
Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them Download PDFInfo
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- CA2545409A1 CA2545409A1 CA002545409A CA2545409A CA2545409A1 CA 2545409 A1 CA2545409 A1 CA 2545409A1 CA 002545409 A CA002545409 A CA 002545409A CA 2545409 A CA2545409 A CA 2545409A CA 2545409 A1 CA2545409 A1 CA 2545409A1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| IL15886803A IL158868A0 (en) | 2003-11-13 | 2003-11-13 | Methods of generating and using stem cells enriched with immature primitive progenitor |
| IL158868 | 2003-11-13 | ||
| PCT/IL2004/001018 WO2005047494A2 (en) | 2003-11-13 | 2004-11-08 | Haematopoietic stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them |
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| CA2545409A1 true CA2545409A1 (en) | 2005-05-26 |
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| CA002545409A Abandoned CA2545409A1 (en) | 2003-11-13 | 2004-11-08 | Stem cells suitable for transplantation, their preparation and pharmaceutical compositions comprising them |
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| IL (2) | IL158868A0 (enExample) |
| NO (1) | NO335515B1 (enExample) |
| WO (1) | WO2005047494A2 (enExample) |
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| US20050271639A1 (en) * | 2002-08-22 | 2005-12-08 | Penn Marc S | Genetically engineered cells for therapeutic applications |
| CN101495623B (zh) | 2006-03-24 | 2013-09-11 | 儿童医疗中心有限公司 | 调节造血干细胞生长的方法 |
| EP2679221B1 (en) | 2006-10-20 | 2020-09-23 | Children's Medical Center Corporation | Method to enhance tissue regeneration |
| WO2008073748A1 (en) | 2006-12-08 | 2008-06-19 | University Of Rochester | Expansion of hematopoietic stem cells |
| CA2682469A1 (en) | 2007-03-30 | 2008-10-09 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
| US8198083B1 (en) | 2007-10-31 | 2012-06-12 | William Gunter Loudon | Organotypic slices of the central nervous system |
| WO2009079451A2 (en) | 2007-12-14 | 2009-06-25 | The Cleveland Clinic Foundation | Compositions and methods of promoting wound healing |
| EP3031907B1 (en) | 2008-11-06 | 2021-01-06 | Indiana University Research and Technology Corporation | Materials and methods to enhance hematopoietic stem cells engraftment procedures |
| US20120283315A1 (en) | 2009-08-28 | 2012-11-08 | Penn Marc S | Sdf-1 delivery for treating ischemic tissue |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| MX359398B (es) | 2011-09-30 | 2018-09-27 | Bluebird Bio Inc | Compuestos para transduccion viral mejorada. |
| WO2013082243A1 (en) * | 2011-12-02 | 2013-06-06 | Fate Therapeutics, Inc. | Enhanced stem cell composition |
| EP3297694A1 (en) | 2015-05-21 | 2018-03-28 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| EP3413896B1 (en) | 2016-02-12 | 2021-03-17 | Bluebird Bio, Inc. | Vcn enhancer compositions and methods of using the same |
| CA3014078A1 (en) | 2016-02-12 | 2017-08-17 | Bluebird Bio, Inc. | Vcn enhancer compositions and methods of using the same |
| GB201807944D0 (en) * | 2018-05-16 | 2018-06-27 | Ospedale San Raffaele Srl | Compositions and methods for haematopoietic stem cell transplantation |
| WO2022054999A1 (ko) * | 2020-09-14 | 2022-03-17 | 주식회사 제너로스 | 생착능이 증가된 줄기세포의 제조 방법 |
| WO2023010068A2 (en) * | 2021-07-28 | 2023-02-02 | Cartesian Therapeutics, Inc. | Multiprotein-engineered cells secreting a multispecific antibody |
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| US4588585A (en) * | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
| US4737462A (en) * | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| US5017691A (en) * | 1986-07-03 | 1991-05-21 | Schering Corporation | Mammalian interleukin-4 |
| JP2874751B2 (ja) | 1986-04-09 | 1999-03-24 | ジェンザイム・コーポレーション | 希望する蛋白質をミルク中へ分泌する遺伝子移植動物 |
| US4879111A (en) * | 1986-04-17 | 1989-11-07 | Cetus Corporation | Treatment of infections with lymphokines |
| US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US4904584A (en) * | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
| EP0386476B1 (en) * | 1989-02-06 | 1994-07-13 | Mitsubishi Petrochemical Co., Ltd. | Process for producing L-alanine |
| US6326198B1 (en) * | 1990-06-14 | 2001-12-04 | Regents Of The University Of Michigan | Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5837539A (en) * | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
| US6447766B1 (en) * | 1993-06-08 | 2002-09-10 | Smithkline Beecham Corporation | Method of mobilizing hematopoietic stem cells |
| US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| WO1996037208A1 (en) * | 1995-05-25 | 1996-11-28 | Baxter International Inc. | Allogeneic cell therapy for cancer following allogeneic stem cell transplantation |
| US5928638A (en) * | 1996-06-17 | 1999-07-27 | Systemix, Inc. | Methods for gene transfer |
| US6090622A (en) * | 1997-03-31 | 2000-07-18 | The Johns Hopkins School Of Medicine | Human embryonic pluripotent germ cells |
| US6511958B1 (en) * | 1997-08-14 | 2003-01-28 | Sulzer Biologics, Inc. | Compositions for regeneration and repair of cartilage lesions |
| IL135068A (en) * | 1997-09-29 | 2004-03-28 | Point Therapeutics Inc | Stimulation of hematopoietic cells in vitro |
| US6132708A (en) * | 1997-10-10 | 2000-10-17 | Oregon Health Sciences University | Liver regeneration using pancreas cells |
| US6248587B1 (en) * | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| EP1061949B1 (en) * | 1998-03-03 | 2009-07-15 | University of Southern California | Cytokines and mitogens to inhibit graft-versus-host disease |
| US6383481B1 (en) * | 1998-03-30 | 2002-05-07 | Japan Immunoresearch Laboratories Co., Ltd. | Method for transplantation of hemopoietic stem cells |
| US6184035B1 (en) * | 1998-11-18 | 2001-02-06 | California Institute Of Technology | Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells |
| US6280718B1 (en) * | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
| US6436704B1 (en) * | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
| DK2371361T3 (da) * | 2001-07-31 | 2019-08-19 | Genzyme Corp | Fremgangsmåder til mobilisering af progenitor-/stamceller |
| AU2002347563A1 (en) * | 2001-12-06 | 2003-06-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of cd34+ hematopoietic progenitor cells for the treatment of cns disorders |
| IL146970A0 (en) * | 2001-12-06 | 2002-08-14 | Yeda Res & Dev | Migration of haematopoietic stem cells and progenitor cells to the liver |
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2003
- 2003-11-13 IL IL15886803A patent/IL158868A0/xx unknown
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2004
- 2004-11-08 US US10/578,291 patent/US20080025957A1/en not_active Abandoned
- 2004-11-08 WO PCT/IL2004/001018 patent/WO2005047494A2/en not_active Ceased
- 2004-11-08 AU AU2004288879A patent/AU2004288879B2/en not_active Ceased
- 2004-11-08 CA CA002545409A patent/CA2545409A1/en not_active Abandoned
- 2004-11-08 JP JP2006539071A patent/JP2007511219A/ja active Pending
- 2004-11-08 EP EP04799327.4A patent/EP1682653B1/en not_active Expired - Lifetime
- 2004-11-08 ES ES04799327.4T patent/ES2534724T3/es not_active Expired - Lifetime
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2006
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- 2006-06-12 NO NO20062709A patent/NO335515B1/no not_active IP Right Cessation
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2011
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2012
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Also Published As
| Publication number | Publication date |
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| IL158868A0 (en) | 2004-05-12 |
| AU2004288879B2 (en) | 2011-06-16 |
| IL175430A0 (en) | 2006-09-05 |
| WO2005047494A2 (en) | 2005-05-26 |
| AU2004288879A1 (en) | 2005-05-26 |
| ES2534724T3 (es) | 2015-04-27 |
| EP1682653B1 (en) | 2015-03-25 |
| US8367057B2 (en) | 2013-02-05 |
| JP2012125249A (ja) | 2012-07-05 |
| US20080025957A1 (en) | 2008-01-31 |
| JP2007511219A (ja) | 2007-05-10 |
| NO335515B1 (no) | 2014-12-22 |
| NO20062709L (no) | 2006-08-11 |
| US20110268712A1 (en) | 2011-11-03 |
| EP1682653A2 (en) | 2006-07-26 |
| IL175430A (en) | 2015-01-29 |
| WO2005047494A3 (en) | 2005-06-23 |
| JP5547221B2 (ja) | 2014-07-09 |
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| FZDE | Discontinued |
Effective date: 20160919 |