NO323768B1 - Humant monoklonalt antistoff, isolert polynukleotid, vertscelle, biologisk funksjonell vektor, fremgangsmate for pavisning av respiratorisk syncytialt virus (RSV), sett, samt vektor. - Google Patents
Humant monoklonalt antistoff, isolert polynukleotid, vertscelle, biologisk funksjonell vektor, fremgangsmate for pavisning av respiratorisk syncytialt virus (RSV), sett, samt vektor. Download PDFInfo
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- NO323768B1 NO323768B1 NO19950881A NO950881A NO323768B1 NO 323768 B1 NO323768 B1 NO 323768B1 NO 19950881 A NO19950881 A NO 19950881A NO 950881 A NO950881 A NO 950881A NO 323768 B1 NO323768 B1 NO 323768B1
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- antibody
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1006—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against or targeting material from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Oncology (AREA)
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- Pain & Pain Management (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94551592A | 1992-09-16 | 1992-09-16 | |
| PCT/US1993/008786 WO1994006448A1 (fr) | 1992-09-16 | 1993-09-16 | Anticorps monoclonaux neutralisateurs humains contre le virus respiratoire syncytial |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950881D0 NO950881D0 (no) | 1995-03-07 |
| NO950881L NO950881L (no) | 1995-05-15 |
| NO323768B1 true NO323768B1 (no) | 2007-07-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19950881A NO323768B1 (no) | 1992-09-16 | 1995-03-07 | Humant monoklonalt antistoff, isolert polynukleotid, vertscelle, biologisk funksjonell vektor, fremgangsmate for pavisning av respiratorisk syncytialt virus (RSV), sett, samt vektor. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5762905A (fr) |
| EP (1) | EP0671927B1 (fr) |
| JP (1) | JP3976333B2 (fr) |
| AT (1) | ATE231002T1 (fr) |
| AU (1) | AU686113B2 (fr) |
| CA (1) | CA2144043C (fr) |
| DE (1) | DE69332643T2 (fr) |
| DK (1) | DK0671927T3 (fr) |
| ES (1) | ES2191016T3 (fr) |
| FI (2) | FI108991B (fr) |
| NO (1) | NO323768B1 (fr) |
| WO (1) | WO1994006448A1 (fr) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824307A (en) | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| GB9207479D0 (en) * | 1992-04-06 | 1992-05-20 | Scotgen Ltd | Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man |
| US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
| WO1997010846A1 (fr) * | 1995-09-18 | 1997-03-27 | Intracel Corporation | Anticorps monoclonaux neutralisants diriges contre le virus syncytial respiratoire |
| EP0977590A4 (fr) * | 1996-11-01 | 2001-03-14 | Smithkline Beecham Corp | Anticorps monoclonaux humains |
| ITRM960808A1 (it) * | 1996-11-26 | 1998-05-26 | Rossolini Gianmaria | Immunoconiugati comprendenti anticorpi monoclonali umani o frammenti di essi per diagnosi in vivo e terapia |
| FR2758331B1 (fr) * | 1997-01-14 | 1999-03-05 | Univ Bourgogne | Nouveaux moyens pour le diagnostic, la prevention et le traitement vis-a-vis de contaminations ou d'infections par des virus a tropisme muqueux |
| EP2311490A3 (fr) | 1998-07-13 | 2011-05-04 | Board of Regents, The University of Texas System | L'utilisation d'anticorps vis-à-vis des aminophospholipides pour le traitement du cancer |
| CO5280147A1 (es) * | 1999-05-18 | 2003-05-30 | Smithkline Beecham Corp | Anticuerpo humano monoclonal |
| US7229619B1 (en) | 2000-11-28 | 2007-06-12 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| JP4992068B2 (ja) * | 2000-01-27 | 2012-08-08 | メディミューン，エルエルシー | 超高親和性中和抗体 |
| EP2341075A1 (fr) * | 2000-03-01 | 2011-07-06 | MedImmune, LLC | Anticorps reconnaissant la protein f du virus respiratoire syncytial (rsv) |
| US20050175986A1 (en) * | 2000-05-09 | 2005-08-11 | Smit Kline Beecham Corporation | Human monoclonal antibody |
| AU2002210384B2 (en) * | 2000-10-17 | 2006-10-19 | Besst-Test Aps | Assay for directly detecting a RS virus related biological cell in a body fluid sample |
| US7179900B2 (en) | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| US6855493B2 (en) | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| CA2466025A1 (fr) * | 2001-11-02 | 2003-08-07 | Centocor, Inc. | Proteines du vrs, anticorps, compositions, procedes et utilisations |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| US6919077B2 (en) * | 2002-09-27 | 2005-07-19 | Aids Research, Llc | LFA-1 alpha subunit antibodies and methods of use |
| US7070786B2 (en) * | 2003-06-06 | 2006-07-04 | Centocor, Inc. | RSV proteins, antibodies, compositions, methods and uses |
| WO2005060520A2 (fr) * | 2003-11-25 | 2005-07-07 | Dana-Farber Cancer Institute, Inc. | Anticorps diriges contre sras-cov et methodes d'utilisation de ceux-ci |
| US7700720B2 (en) | 2004-09-21 | 2010-04-20 | Medimmune, Llc | Antibodies against and methods for producing vaccines for respiratory syncytial virus |
| WO2006050166A2 (fr) * | 2004-10-29 | 2006-05-11 | Medimmune, Inc. | Methodes de prevention et de traitement des infections a rsv et des etats pathologiques associes |
| US20100040606A1 (en) * | 2006-03-06 | 2010-02-18 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| HUE033630T2 (en) | 2006-10-02 | 2017-12-28 | Squibb & Sons Llc | CXCR4 binding human antibodies and their use |
| ES2678060T3 (es) | 2006-12-01 | 2018-08-08 | E. R. Squibb & Sons, L.L.C. | Anticuerpos, en particular, anticuerpos humanos, que se unen a CD22 y usos de los mismos |
| CL2007003622A1 (es) | 2006-12-13 | 2009-08-07 | Medarex Inc | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. |
| MX2009006277A (es) | 2006-12-14 | 2009-07-24 | Medarex Inc | Anticuerpos humanos que se enlazan a cd70 y usos de los mismos. |
| JP2010534057A (ja) * | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| EP1997830A1 (fr) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | Molécules à liaison spécifiques RSV et leur moyen de fabrication |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| US8852608B2 (en) | 2009-02-02 | 2014-10-07 | Medimmune, Llc | Antibodies against and methods for producing vaccines for respiratory syncytial virus |
| US20110033389A1 (en) * | 2009-04-29 | 2011-02-10 | Zhifeng Chen | Modified antibodies for passive immunotherapy |
| DK2464664T3 (da) | 2009-08-13 | 2016-01-18 | Crucell Holland Bv | Antistoffer mod humant respiratorisk syncytialvirus (rsv) og fremgangsmåder til anvendelse deraf |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| NZ603488A (en) | 2010-07-09 | 2015-02-27 | Crucell Holland Bv | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| IL210093A0 (en) * | 2010-12-19 | 2011-06-30 | David Helman | Membrane bound reporter molecules and their use in cell sorting |
| CL2011003002A1 (es) * | 2011-11-25 | 2012-05-25 | Univ Pontificia Catolica Chile | Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento. |
| UY34887A (es) | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法 |
| JO3555B1 (ar) | 2015-10-29 | 2020-07-05 | Merck Sharp & Dohme | جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري |
| IL293585B2 (en) | 2016-10-21 | 2023-11-01 | Adimab Llc | Respiratory syncytial virus antibodies and methods for their production and use |
| JP2020503843A (ja) | 2016-10-21 | 2020-02-06 | アディマブ， エルエルシー | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
| US11479600B2 (en) | 2016-10-21 | 2022-10-25 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| RU2019138507A (ru) | 2017-05-02 | 2021-06-02 | Мерк Шарп И Доум Корп. | Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1 |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| SG11202100746WA (en) | 2018-07-25 | 2021-03-30 | Innovent Biologics Suzhou Co Ltd | Anti-tigit antibody and use thereof |
| CN109762067B (zh) | 2019-01-17 | 2020-02-28 | 北京天广实生物技术股份有限公司 | 结合人Claudin 18.2的抗体及其用途 |
| MX2022010665A (es) | 2020-02-27 | 2022-09-23 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Anticuerpos que se unen al receptor de interleucina 4 (il4r) y usos de los mismos. |
| WO2021202463A1 (fr) | 2020-03-30 | 2021-10-07 | Danisco Us Inc | Anticorps anti-rsv |
| US20230272086A1 (en) | 2020-05-12 | 2023-08-31 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | St2 antigen binding protein |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5332567A (en) * | 1989-08-24 | 1994-07-26 | Immunomedics | Detection and treatment of infections with immunoconjugates |
| WO1991016074A1 (fr) * | 1990-04-19 | 1991-10-31 | Medimmune, Inc. | Administration d'anticorps monoclonaux contre des virus respiratoires |
| AU644210B2 (en) * | 1990-07-19 | 1993-12-02 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Improved immunotherapeutic method of preventing or treating viral respiratory tract disease |
| GB9019812D0 (en) * | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
-
1993
- 1993-09-16 CA CA002144043A patent/CA2144043C/fr not_active Expired - Lifetime
- 1993-09-16 US US08/162,102 patent/US5762905A/en not_active Expired - Lifetime
- 1993-09-16 ES ES93921646T patent/ES2191016T3/es not_active Expired - Lifetime
- 1993-09-16 AU AU49271/93A patent/AU686113B2/en not_active Ceased
- 1993-09-16 AT AT93921646T patent/ATE231002T1/de not_active IP Right Cessation
- 1993-09-16 JP JP50832994A patent/JP3976333B2/ja not_active Expired - Fee Related
- 1993-09-16 DE DE69332643T patent/DE69332643T2/de not_active Expired - Fee Related
- 1993-09-16 DK DK93921646T patent/DK0671927T3/da active
- 1993-09-16 EP EP93921646A patent/EP0671927B1/fr not_active Expired - Lifetime
- 1993-09-16 WO PCT/US1993/008786 patent/WO1994006448A1/fr active IP Right Grant
-
1995
- 1995-03-07 NO NO19950881A patent/NO323768B1/no unknown
- 1995-03-13 FI FI951164A patent/FI108991B/fi not_active IP Right Cessation
-
2002
- 2002-01-31 FI FI20020184A patent/FI111553B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0671927B1 (fr) | 2003-01-15 |
| NO950881D0 (no) | 1995-03-07 |
| FI108991B (fi) | 2002-05-15 |
| DE69332643T2 (de) | 2003-11-27 |
| AU4927193A (en) | 1994-04-12 |
| WO1994006448A1 (fr) | 1994-03-31 |
| JP3976333B2 (ja) | 2007-09-19 |
| ES2191016T3 (es) | 2003-09-01 |
| CA2144043A1 (fr) | 1994-03-31 |
| EP0671927A1 (fr) | 1995-09-20 |
| FI20020184A (fi) | 2002-01-31 |
| FI951164A (fi) | 1995-05-12 |
| EP0671927A4 (fr) | 1997-05-21 |
| CA2144043C (fr) | 2005-01-18 |
| JPH08505520A (ja) | 1996-06-18 |
| AU686113B2 (en) | 1998-02-05 |
| ATE231002T1 (de) | 2003-02-15 |
| DE69332643D1 (de) | 2003-02-20 |
| US5762905A (en) | 1998-06-09 |
| DK0671927T3 (da) | 2003-04-22 |
| FI951164A0 (fi) | 1995-03-13 |
| FI111553B (fi) | 2003-08-15 |
| NO950881L (no) | 1995-05-15 |
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